Enzyme News and Research

RSS

White blood cell count as a prognostic indicator of COVID-19

Based on a new study, researchers concluded WBC count variations worsen clinical outcomes such as severity, mortality, and hospital discharge rates leading to a poorer prognosis in COVID-19 patients.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

A recent study reported the abrogation of inhibition of the NK cells by a SARS-CoV-2-encoded protein presented by HLA-E.

23 Feb 2022

Study explores the impact of COVID-19 on pancreatic cells

New study findings showed that SARS-CoV-2 caused a productive yet restricted infection of pancreatic islet cells and an insignificant inflammatory response.

23 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

Pre-existing B-cell immunity against SARS-CoV-2 not detected in pre-pandemic samples

A recent study investigates samples solated from unexposed individuals pre-pandemic to determine the presence of pre-existing SARS-CoV-2 B-cell immunity.

22 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Novel platform can become a potential approach for personalized cancer treatments

Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.

22 Feb 2022

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease.

22 Feb 2022

Study explores the decline in viral load and immune response in COVID-19 patients

Researchers described the changes in viral ribonucleic acid the decline in viral load, and the immune response of SARS-CoV-2-infected patients, in a new preprint study.

22 Feb 2022

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Researchers compared the secondary attack rates SARS-CoV-2 Omicron and Delta variants of concern in Norwegian households.

22 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Study suggests anti-SARS-CoV-2 antibodies may persist lifelong post-infection

Researchers attempted to delineate the duration and stability of anti-SARS-CoV-2 antibodies in patients who had recovered from the COVID-19 infection.

22 Feb 2022

Time-based sensitivity of COVID-19 serological testing

In a recent study under consideration at Scientific Reports and posted to the Research Square* preprint server, researchers evaluated the impact of time on the sensitivity of four severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays using samples from the coronavirus disease 2019 (COVID-19) staff testing of antibody responses study(Co-Stars) in the United Kingdom (UK).

22 Feb 2022

Research explains how SARS-CoV-2 variants evade some antibodies

A recent study published in the iScience Journal assessed the influence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on coronavirus disease 2019 (COVID-19) infectivity and viral neutralization.

22 Feb 2022

Using IgG antibody assay to Identify natural SARS-CoV-2 infection in vaccinees

A recent study published in the journal of Mayo Clinic Proceedings predicted the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) natural infection in vaccinated individuals.

21 Feb 2022

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal spread and geographic distribution of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) genomic variants.

21 Feb 2022

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Researchers investigate the potential of picolinic acid (PA) as an anti-SARS-CoV-2 treatment option.

21 Feb 2022

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

21 Feb 2022

Enzyme News and Research

White blood cell count as a prognostic indicator of COVID-19

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

Study explores the impact of COVID-19 on pancreatic cells

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

Pre-existing B-cell immunity against SARS-CoV-2 not detected in pre-pandemic samples

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Novel platform can become a potential approach for personalized cancer treatments

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Study explores the decline in viral load and immune response in COVID-19 patients

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Study suggests anti-SARS-CoV-2 antibodies may persist lifelong post-infection

Time-based sensitivity of COVID-19 serological testing

Research explains how SARS-CoV-2 variants evade some antibodies

Using IgG antibody assay to Identify natural SARS-CoV-2 infection in vaccinees

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo