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NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

Chemotherapy drugs to treat breast cancer may promote muscle mitochondrial dysfunction, according to new research. Dysfunctional mitochondria, the energy centers of the cells, may contribute to fatigue and weakness that some people with breast cancer experience through the course of disease treatment.

5 Oct 2018

CBT for insomnia may slow or reverse cortical atrophy in patients with co-morbid fibromyalgia

Preliminary findings from a pilot study suggest that cognitive behavioral therapy for insomnia may slow or even reverse the atrophy of cortical gray matter in patients who have co-morbid fibromyalgia.

3 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Eisai's antiepileptic drug receives FDA approval to treat partial-onset seizures in pediatric patients

Eisai Co., Ltd. announced today that its U.S. subsidiary Eisai Inc. received approval from the U.S. Food and Drug Administration for an indication expansion for Eisai's antiepileptic drug Fycompa (perampanel) to cover partial-onset seizures in pediatric patients with epilepsy 4 years of age and older.

1 Oct 2018

FDA approves new drug for treatment of lung disease caused by Mycobacterium avium complex

The U.S. Food and Drug Administration today approved a new drug, Arikayce, for the treatment of lung disease caused by a group of bacteria, Mycobacterium avium complex in a limited population of patients with the disease who do not respond to conventional treatment.

29 Sep 2018

Patients report troubling health issues even up to two years after arthroscopic hip surgery

Up to two years following elective, arthroscopic hip surgery, a substantial proportion of patients reported troubling new health issues ranging from sleep problems, to arthritis to cardiovascular disease.

29 Sep 2018

Cancer undercuts ability of normal cells to consume glucose, finds study

Cancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact consuming so much glucose that one method for imaging cancer simply looks for areas of extreme glucose consumption - where there is consumption, there is cancer.

29 Sep 2018

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

The U.S. Food and Drug Administration today approved Libtayo (cemiplimab-rwlc) injection for intravenous use for the treatment of patients with metastatic cutaneous squamous cell carcinoma or locally advanced CSCC who are not candidates for curative surgery or curative radiation.

28 Sep 2018

Microglia lead to increased neuro-inflammation in fibromyalgia patients, finds study

A study by Massachusetts General Hospital researchers - collaborating with a team at the Karolinska Institutet in Sweden - has documented for the first time widespread inflammation in the brains of patients with the poorly understood condition called fibromyalgia.

28 Sep 2018

Verastem Oncology selects US Bioservices to dispense COPIKTRA capsules

US Bioservices, a specialty pharmacy that is a part of AmerisourceBergen, today announced that it has been selected by Verastem OncologyTM to dispense COPIKTRA (duvelisib) capsules.

28 Sep 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today positive topline results from the interim analysis of the ENVISION Phase 3 Study of givosiran, an investigational RNAi therapeutic targeting aminolevulinic acid synthase 1 for the treatment of acute hepatic porphyria.

27 Sep 2018

New drug to treat Parkinson's disease psychosis do not pose greater risk of death

In the wake of media and public reports about increased mortality linked to a new drug for treating Parkinson's disease psychosis -- a symptom of the progressive nervous system disorder in which patients experience hallucinations and delusions -- researchers at University of California San Diego School of Medicine conducted a retrospective study of qualifying patients in the UC San Diego Health system, concluding that the new drug, pimavanserin, did not pose a statistically significant greater risk of death.

27 Sep 2018

Third case of monkey pox confirmed in UK

Officials from Public Health England (PHE) have confirmed yesterday (26th September 2018) that a third person in UK has been diagnosed with monkey pox. While the first two patients had most likely picked up the infection from Nigeria, this third infection has occurred in a healthcare worker who was treating one of the first two infected patients at Blackpool Victoria Hospital.

26 Sep 2018

Researchers develop promising allergy vaccine for hay fever

Using sugar molecules researchers from the University of Copenhagen have developed a new vaccine for hay fever that may reduce treatment times and increase the effect of treatments.

26 Sep 2018

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Japanese scientists have revealed a biological "switch" that influences whether an immature blood cell would develop into a red blood cell or a subtype of white blood cell called myeloid cells in response to infection or inflammation within the body.

26 Sep 2018

Digital CBT can improve insomnia symptoms, daytime functioning and overall health

Treating insomnia with digital programs can improve insomnia symptoms, daytime functioning and overall health, a new study from the University of Oxford and Northwestern Medicine has found.

26 Sep 2018

Activation of glial cells causes inflammation in the brain of fibromyalgia patients

The causes of the difficult-to-treat pain syndrome fibromyalgia are largely unknown. Using PET brain imaging, researchers at Karolinska Institutet and Harvard University have now shown that glial cells - the central nervous system's immune cells - are activated in the brains of patients with fibromyalgia. The finding opens the way for new therapies

25 Sep 2018

Fatigue News and Research

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

CBT for insomnia may slow or reverse cortical atrophy in patients with co-morbid fibromyalgia

Genetic variants reveal novel therapeutic targets for chronic kidney disease

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Eisai's antiepileptic drug receives FDA approval to treat partial-onset seizures in pediatric patients

FDA approves new drug for treatment of lung disease caused by Mycobacterium avium complex

Patients report troubling health issues even up to two years after arthroscopic hip surgery

Cancer undercuts ability of normal cells to consume glucose, finds study

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

Microglia lead to increased neuro-inflammation in fibromyalgia patients, finds study

Verastem Oncology selects US Bioservices to dispense COPIKTRA capsules

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

New drug to treat Parkinson's disease psychosis do not pose greater risk of death

Third case of monkey pox confirmed in UK

Researchers develop promising allergy vaccine for hay fever

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Digital CBT can improve insomnia symptoms, daytime functioning and overall health

Activation of glial cells causes inflammation in the brain of fibromyalgia patients

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