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Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

Researchers identify a novel RSV variant associated with prolonged infection

Researchers examine pathogen or host genetic risk factors for RSV infection, as well as whether certain viral variants are associated with prolonged infection.

20 Nov 2022

UH researcher aims to find causal pathways to developmental disabilities among children in rural Zambia

Of the 2.6 billion children in the world, 11% or 291.2 million are estimated to have one of four developmental disabilities – epilepsy, intellectual disability, vision loss and hearing loss. Ninety-five percent of these children live in low- and middle-income countries, predominantly in sub-Saharan Africa and South Asia, according to recent estimates.

20 Nov 2022

New AI blood testing technology detects more than 80% of liver cancers

A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people.

20 Nov 2022

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Researchers detected a swine influenza A virus (IAV)-infected patient in routine surveillance at the National Influenza Center in Denmark. The detected influenza variant appeared distinct from any variant found previously in Denmark.

18 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

Scientists have developed a clinical WGS workflow that can detect transmission events of a pathogen before they become dominant.

18 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

Researchers validated monkeypox virus (MPXV) quantitative polymerase chain reaction (qPCR) assays.

17 Nov 2022

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

The SARS-CoV-2 Deltacron does not exhibit higher transmissibility or immune evasion than the Omicron BA.1 variant.

16 Nov 2022

Whole genome sequencing could help to reduce the spread of drug-resistant bacteria in hospitals

The spread of antibiotic-resistant bacteria in hospitals could be greatly reduced thanks to research by The University of Queensland and Queensland Health.

16 Nov 2022

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

16 Nov 2022

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

A collaborative study led by the University of Oxford as part of the UK's 100,000 Genomes Project, published in Nature Genetics today, has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukemia (CLL) and associated these with clinical outcomes.

16 Nov 2022

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Lung cancer is the leading cause of cancer deaths globally and a top cause of cancer deaths in the Military Health System.

15 Nov 2022

New guidance lays out the key elements to obtain participant consent for genomics research in Canada

How can Canada optimize the impact of human genomic sequencing to increase our understanding of disease? New guidance in CMAJ (Canadian Medical Association Journal) lays out the key elements for obtaining patient consent for researchers and policymakers in this growing field.

15 Nov 2022

Metabolomic study of genetic regulation of biochemical individuality

Researchers systematically investigated the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites.

15 Nov 2022

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

During the conference, we caught up with some of the speakers to learn more about their work, what they were presenting, and their thoughts about the future of Oncology and Precision Medicine.

15 Nov 2022

The origin of COVID-19: wildlife trade rather than laboratory leak?

A recent opinion piece published in PNAS discussed the sequence of events concerning the COVID-19 pandemic to provide evidence against the alleged leak of SARS-CoV-2 and the Ebola virus from viral research laboratories in Wuhan, China, and West Africa, respectively.

15 Nov 2022

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions - such as cell types or tissues.

14 Nov 2022

Genome News and Research

Rutgers scientists develop new approach to effectively shut down viral infections

Researchers identify a novel RSV variant associated with prolonged infection

UH researcher aims to find causal pathways to developmental disabilities among children in rural Zambia

New AI blood testing technology detects more than 80% of liver cancers

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Scientists explore bat sarbecovirus isolation in Japan

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

Whole genome sequencing could help to reduce the spread of drug-resistant bacteria in hospitals

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

New guidance lays out the key elements to obtain participant consent for genomics research in Canada

Metabolomic study of genetic regulation of biochemical individuality

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

The origin of COVID-19: wildlife trade rather than laboratory leak?

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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