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SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

SCYNEXIS, Inc., a biotechnology company delivering innovative therapies for difficult-to-treat and often life-threatening infections, today announced positive results from the first interim efficacy analysis of the ongoing FURI study.

1 Feb 2019

Computational model of the heart’s mitral valve enables customized care for patients

Engineers at The University of Texas at Austin have developed a new noninvasive technique for simulating repairs to the heart's mitral valve with levels of accuracy reliable enough for use in a clinical setting.

30 Jan 2019

New insight into anti-malaria drug

Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for centuries. The effectiveness was investigated by the Chinese researcher Tu Youyou.

29 Jan 2019

Researchers identify why heart attack triggers arrhythmia in some people

A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.

29 Jan 2019

New drug compounds show promise in treating acute myeloid leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

29 Jan 2019

EU research project is studying the effect of endocrine disruptors on metabolism

January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved.

28 Jan 2019

Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis

The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ions.

25 Jan 2019

Norwegian scientists discover new small molecule drug to treat prostate cancer

Professor Fahri Saatcioglu at University of Oslo's Department of Biosciences (IBV) heads a research group investigating how androgens - male sex hormones - affect the risk of being affected by prostate cancer.

24 Jan 2019

Graphene Flagship project studies impact of graphene and related materials on our health

As the drive to commercialize graphene continues, it is important that all safety aspects are thoroughly researched and understood.

22 Jan 2019

Study reveals potential pathway for endothelial cells to avoid apoptosis

Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth.

17 Jan 2019

Yeast model may pave way for development of novel therapies for metabolic disorders

There are hundreds of metabolic disorders -- including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria.

17 Jan 2019

Cobra Biologics announces appointment of Dr Darrell Sleep as Director of Innovation

Cobra Biologics, an international CDMO for biologics and pharmaceuticals, today announced the appointment of Dr Darrell Sleep as Director of Innovation.

From Charles River 16 Jan 2019

Reviewing applications of advanced materials in drug delivery and biomedicine

The Graphene family of materials has emerged as one of the most useful new age nano-biomaterials. Graphene-based materials exhibit excellent physicochemical properties, such as high electrical conductivity, mechanical strength, and high surface area with π-conjugated carbon atoms stacked to form honeycomb structure, suitable for binding other molecules.

11 Jan 2019

Sleep Research Society selects four outstanding scientists as recipients of 2019 SRS awards

The Sleep Research Society has selected four outstanding sleep and circadian scientists as recipients of the 2019 Sleep Research Society awards, which recognize excellence in sleep and circadian research.

11 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

New “drug sponge” could reduce chemotherapy side effects

Researchers have developed a 3D polymer sponge that absorbs excess chemotherapy drugs from the bloodstream following treatment.

9 Jan 2019

Study: Rutin found in fruits and vegetables protect mice against snake venom

Rutin, a bioflavonoid found in certain vegetables and fruits, protects mice against snake venom by minimizing bleeding and inflammation, according to a study performed at the Butantan Institute, a research institution belonging to the government of São Paulo State in Brazil.

9 Jan 2019

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

The Wistar Institute, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc., announce that the FDA has approved the initiation of a first-in-human clinical trial investigating the safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody therapeutic technology for the prevention of Zika virus infection.

9 Jan 2019

KU researcher studies how estrogen may protect menisci between thighbone and shinbone

More than 30 million Americans suffer from osteoarthritis of the knee, according to the Centers for Disease Control and Prevention.

9 Jan 2019

Pitt study delves deeper into how electrical stimulation activates neurons

Electrical stimulation of the brain is common practice in neuroscience research and is an increasingly common and effective clinical therapy for a variety of neurological disorders. However, there is limited understanding of why this treatment works at the neural level.

8 Jan 2019

in vivo News and Research

SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

Computational model of the heart’s mitral valve enables customized care for patients

New insight into anti-malaria drug

Researchers identify why heart attack triggers arrhythmia in some people

New drug compounds show promise in treating acute myeloid leukemia

EU research project is studying the effect of endocrine disruptors on metabolism

Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis

Norwegian scientists discover new small molecule drug to treat prostate cancer

Graphene Flagship project studies impact of graphene and related materials on our health

Study reveals potential pathway for endothelial cells to avoid apoptosis

Yeast model may pave way for development of novel therapies for metabolic disorders

Cobra Biologics announces appointment of Dr Darrell Sleep as Director of Innovation

Reviewing applications of advanced materials in drug delivery and biomedicine

Sleep Research Society selects four outstanding scientists as recipients of 2019 SRS awards

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

New “drug sponge” could reduce chemotherapy side effects

Study: Rutin found in fruits and vegetables protect mice against snake venom

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

KU researcher studies how estrogen may protect menisci between thighbone and shinbone

Pitt study delves deeper into how electrical stimulation activates neurons

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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