Cell Death News and Research

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Study to understand how bisphenol-A may promote breast cancer growth

UT Arlington biochemists say their newly published study brings researchers a step closer to understanding how the commonly used synthetic compound bisphenol-A, or BPA, may promote breast cancer growth.

6 Mar 2014

Inflammation and stress combine in bipolar and schizophrenia subtypes

Researchers have found that some individuals with bipolar disorder or schizophrenia have combined stress response and immune dysfunctions.

6 Mar 2014

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.

6 Mar 2014

Expression of MYC gene important for neurogenesis in the spinal cord

Research from Karolinska Institutet in Sweden suggests that the expression of the so called MYC gene is important and necessary for neurogenesis in the spinal cord. The findings are being published in the journal EMBO Reports.

6 Mar 2014

Georgia Regents Medical Center explores new treatment for Parkinson's disease-related constipation

Georgia Regents Medical Center is among about a dozen centers nationally exploring the potential of a new drug that may offer relief to people with Parkinson's who have failed standard approaches to treating constipation.

5 Mar 2014

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

The international consortium A-PARADDISE (Anti-Parasitic Drug Discovery in Epigenetics), coordinated by Inserm, has just obtained funds of €6 million from the European Commission to conduct large-scale testing of innovative therapies against four neglected parasitic diseases: schistosomiasis, leishmaniasis, Chagas disease and malaria.

4 Mar 2014

UCLA develops experimental treatment that eliminates acute type of leukemia in mice

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center has developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects.

28 Feb 2014

UCLA scientists developed experimental treatment that eradicates acute type of leukemia in mice

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center have developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects. The drug works by blocking two important metabolic pathways that the leukemia cells need to grow and spread.

25 Feb 2014

CardioCell announces new clinical trials using allogeneic stem-cell therapy to treat subjects with AMI

CardioCell LLC announces two new clinical trials using its allogeneic stem-cell therapy to treat subjects with acute myocardial infarction (AMI), a problem facing more than 1.26 million Americans annually.

20 Feb 2014

Chronic intake of marijuana protects critical immune tissue from damaging effects of HIV infection

New evidence that chronic intake of THC, the primary psychoactive ingredient in marijuana, can protect critical immune tissue in the gut from the damaging effects of HIV infection is reported in AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

19 Feb 2014

Phasefocus’ KTP associate Dr Suman receives runners up spot for Cellular Heaven and Hell time-lapse video

Phase Focus Ltd (Phasefocus), the company that is revolutionizing microscopy and imaging with the Phasefocus Virtual Lens® technology, reports on the Celldance competition results held at the recent annual ASCB meeting. KTP associate, Dr Rakesh Suman, was runner up with his video entitled "Cellular Heaven & Hell."

From Phase Focus Limited 18 Feb 2014

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

A common compound known to fight lymphoma and skin conditions actually has a second method of action that makes it particularly deadly against certain aggressive breast tumors, researchers at Duke Medicine report.

18 Feb 2014

Study shows how Bcl-2 cancer-related protein signals cancer cells to live longer

A team of researchers from Case Western Reserve School of Medicine has discovered how the cancer-related protein Bcl-2 signals cancer cells to live longer.

14 Feb 2014

Researchers demonstrate new approach to treating muscular dystrophy

Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.

12 Feb 2014

Study on heart attacks identifies potential new treatment target for heart disease

Research led by David Lefer, PhD, Professor and Director of the Cardiovascular Center of Excellence at LSU Health Sciences Center New Orleans School of Medicine, demonstrates for the first time cross-talk between two protective signaling molecules during a heart attack.

11 Feb 2014

Combination of infused vitamin C and conventional chemotherapy drugs stops ovarian cancer

Scientists at the University of Kansas Medical Center have determined that high doses of vitamin C, administered intravenously with traditional chemotherapy, helped kill cancer cells while reducing the toxic effects of chemotherapy for some cancer patients.

10 Feb 2014

Researchers find biological weakness in the workings of mutated gene involved in human cancers

NYU Langone Medical Center researchers have found a biological weakness in the workings of the most commonly mutated gene involved in human cancers, known as mutant K-Ras, which they say can be exploited by drug chemotherapies to thwart tumor growth.

10 Feb 2014

Scientists develop new approach to design drugs from genome sequence

In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a potentially general approach to design drugs from genome sequence. As a proof of principle, they identified a highly potent compound that causes cancer cells to attack themselves and die.

10 Feb 2014

Researchers examine link between gender and genetic disorder

A genetic disorder that affects about 1 in every 2,500 births can cause a bewildering array of clinical problems, including brain tumors, impaired vision, learning disabilities, behavioral problems, heart defects and bone deformities. The symptoms and their severity vary among patients affected by this condition, known as neurofibromatosis type 1 (NF1).

9 Feb 2014

Combination of etoposide with compounds that interfere with cell division improves therapeutic window for cancer treatments

A large part of the effort dedicated to cancer research is directed towards the search for combinations of existing drugs-many of which have already been introduced into clinical practice-that permit higher overall survival rates and improvements in the quality of life of cancer patients.

7 Feb 2014

Cell Death News and Research

Study to understand how bisphenol-A may promote breast cancer growth

Inflammation and stress combine in bipolar and schizophrenia subtypes

Scientists reveal how a genetic code variation results in devastating brain diseases

Expression of MYC gene important for neurogenesis in the spinal cord

Georgia Regents Medical Center explores new treatment for Parkinson's disease-related constipation

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

UCLA develops experimental treatment that eliminates acute type of leukemia in mice

UCLA scientists developed experimental treatment that eradicates acute type of leukemia in mice

CardioCell announces new clinical trials using allogeneic stem-cell therapy to treat subjects with AMI

Chronic intake of marijuana protects critical immune tissue from damaging effects of HIV infection

Phasefocus’ KTP associate Dr Suman receives runners up spot for Cellular Heaven and Hell time-lapse video

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Study shows how Bcl-2 cancer-related protein signals cancer cells to live longer

Researchers demonstrate new approach to treating muscular dystrophy

Study on heart attacks identifies potential new treatment target for heart disease

Combination of infused vitamin C and conventional chemotherapy drugs stops ovarian cancer

Researchers find biological weakness in the workings of mutated gene involved in human cancers

Scientists develop new approach to design drugs from genome sequence

Researchers examine link between gender and genetic disorder

Combination of etoposide with compounds that interfere with cell division improves therapeutic window for cancer treatments

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