Central Nervous System News and Research

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Shionogi brings KAPVAY ADHD drug to the U.S market

Shionogi Inc., the U.S.-based group company of Shionogi & Co., Ltd., today announced a true milestone as it marks the first commercial availability for the non-central nervous system stimulant medication KAPVAY™, an extended-release oral formulation of clonidine for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents.

10 Jan 2011

ACADIA raises $15 million through private placement

ACADIA Pharmaceuticals Inc., a biopharmaceutical company utilizing innovative technology to fuel drug discovery and clinical development of novel treatments for central nervous system disorders, today announced that it has entered into a securities purchase agreement for a private placement financing with a select group of institutional investors, including New Enterprise Associates and Venrock.

10 Jan 2011

Researchers identify gene mutation for that is essential for correct protein-processing in cells

A Jackson Laboratory research team led by Professor Patsy Nishina, Ph.D., has identified a mutation in a gene that's essential for correct protein-processing in cells. Defects in protein folding are associated with a variety of abnormalities and diseases.

10 Jan 2011

IDSA releases MRSA treatment guidelines

Physicians now have help in their battle against methicillin resistant Staphylococcus aureus (MRSA), a potentially deadly infection that initially was limited to hospitals and health care facilities but has become a growing problem in healthy children and adults. The Infectious Diseases Society of America (IDSA) has released its first guidelines for the treatment of increasingly common MRSA infections.

7 Jan 2011

Isis Pharmaceuticals announces addition of two new drugs to development pipeline

Isis Pharmaceuticals, announced today that it has added two new drugs to its development pipeline, ISIS-FGFR4Rx and ISIS-STAT3Rx.

7 Jan 2011

Synageva BioPharma, to-BBB to evaluate brain drug delivery technology

Synageva BioPharma Corp. and to-BBB technologies BV, the Dutch drug brain delivery company, have entered into a research collaboration to evaluate the potential of transporting therapeutic proteins across the blood-brain barrier into the central nervous system.

6 Jan 2011

Positive results from OMS201 Phase 1/2 trial in patients undergoing urologic procedures

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system, today announced results from the Phase 1/2 clinical trial of OMS201, the Company's urological PharmacoSurgery™ product candidate.

29 Dec 2010

Study reports ROP18 protein protects parasite in host cell

Researchers at Washington University School of Medicine in St. Louis have learned why changes in a single gene, ROP18, contribute substantially to dangerous forms of the parasite Toxoplasma gondii. The answer has likely moved science a step closer to new ways to beat Toxoplasma and many other parasites.

28 Dec 2010

MiMedx receives notification of Class III certification for HydroFix technology

MiMedx Group, Inc., an integrated developer, manufacturer and marketer of patent protected biomaterial-based products, announced today that it has received notification of the Class III certification for a European product using the Company's proprietary HydroFix technology.

24 Dec 2010

MigreLief releases safe, proven effective supplement for children with migraines

MigreLief, the first name in migraine prevention, releases a safe and proven effective supplement for children of all ages: Children's MigreLief.

24 Dec 2010

Novel method to analyze fatigue through speech

What can scientists learn from watching a group of people sitting around, chatting, playing movies, reading, and happily making new friends? Quite a lot, says University of Melbourne, Australia acoustician Adam Vogel, who carefully observed this sort of group in a fatigue management study he and his colleagues describe this month in The Journal of the Acoustical Society of America.

22 Dec 2010

Researchers perform cord blood cell transplantation to treat child with ischemic brain injury

In three monthly injections, researchers transplanted neurally-committed, autologous cord blood derived cells tagged with iron oxide nanoparticles into the lateral cerebral ventricle of a 16-month old child with severe global hypoxic ischemic brain injury.

22 Dec 2010

Antares Pharma submits NDA for Anturol Gel in patients with overactive bladder

Antares Pharma, today announced the filing of a New Drug Application with the U.S. Food and Drug Administration for Anturol Gel in patients with overactive bladder.

22 Dec 2010

Gene changes during brain development can lead to male genitalia formation in female embryo

Australian scientists have discovered that changes to a gene involved in brain development can lead to testis formation and male genitalia in an otherwise female embryo.

22 Dec 2010

Maternal prenatal supplements boost child's intellectual and motor function

In an area where iron deficiency is prevalent, children of mothers in rural Nepal who received prenatal iron, folic acid and vitamin A supplementation performed better on measures of intellectual and motor functioning compared to offspring of mothers who received vitamin A alone, according to a study in the December 22/29 issue of JAMA.

22 Dec 2010

Ramius/RP Group extend tender offer to acquire Cypress Bioscience

Ramius V&O Acquisition LLC, affiliates of Ramius LLC (collectively, "Ramius") and affiliates of Royalty Pharma (together with Ramius and Purchaser, the "Ramius/RP Group") announced today that the Ramius/RP Group is extending its previously announced tender offer to acquire all of the outstanding shares of common stock of Cypress Bioscience, Inc., a pharmaceutical company engaged in the development of innovative drugs to treat central nervous system (CNS) disorders, until Midnight, January 5, 2011, unless the offer is otherwise extended.

22 Dec 2010

Prenatal iron-folic acid supplementation increases intellectual, motor function in children

In developing countries where iron deficiency is prevalent, prenatal iron-folic acid supplementation increased offspring intellectual and motor functioning during school age, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

22 Dec 2010

Whites with mutations more likely to be susceptible to cocaine abuse

Nearly one in five whites could carry a genetic variant that substantially increases their odds of being susceptible to severe cocaine abuse, according to new research.

21 Dec 2010

Gilenya offers more benefits for MS therapy than previously realized

In September, patients suffering from multiple sclerosis (MS) received the welcome news that the U.S. Food and Drug Administration (FDA) had approved a promising new drug for their condition called Gilenya. Now, a team from The Scripps Research Institute has discovered that this drug's success may involve an unexpected biological mechanism acting within the central nervous system (CNS). This difference may mean that Gilenya offers even more benefits than previously realized and would represent the first MS therapy with direct CNS activities.

21 Dec 2010

Study: Chemotherapy can improve survival rate in older adolescents with leukemia

Research led by St. Jude Children-s Research Hospital investigators will likely impact how acute lymphoblastic leukemia is treated in young adults and shows older adolescent age does not dictate worse outcomes against the most common childhood cancer.

21 Dec 2010

Central Nervous System News and Research

Shionogi brings KAPVAY ADHD drug to the U.S market

ACADIA raises $15 million through private placement

Researchers identify gene mutation for that is essential for correct protein-processing in cells

IDSA releases MRSA treatment guidelines

Isis Pharmaceuticals announces addition of two new drugs to development pipeline

Synageva BioPharma, to-BBB to evaluate brain drug delivery technology

Positive results from OMS201 Phase 1/2 trial in patients undergoing urologic procedures

Study reports ROP18 protein protects parasite in host cell

MiMedx receives notification of Class III certification for HydroFix technology

MigreLief releases safe, proven effective supplement for children with migraines

Novel method to analyze fatigue through speech

Researchers perform cord blood cell transplantation to treat child with ischemic brain injury

Antares Pharma submits NDA for Anturol Gel in patients with overactive bladder

Gene changes during brain development can lead to male genitalia formation in female embryo

Maternal prenatal supplements boost child's intellectual and motor function

Ramius/RP Group extend tender offer to acquire Cypress Bioscience

Prenatal iron-folic acid supplementation increases intellectual, motor function in children

Whites with mutations more likely to be susceptible to cocaine abuse

Gilenya offers more benefits for MS therapy than previously realized

Study: Chemotherapy can improve survival rate in older adolescents with leukemia

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