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Small molecule applications of process Raman spectroscopy

In this interview, Kevin Broadbelt of Thermo Fisher Scientific discusses the small molecule applications of process Raman spectroscopy.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 11 Dec 2023

New insights into how anti-obesity drugs could help prevent kidney disease

Data from Australian researchers could partly explain why a trial of a new drug for diabetes, was recently halted because it was found to be so effective.

8 Dec 2023

New guidelines offer hope for fatigue management in people with inflammatory RMD

Fatigue is common in people with inflammatory rheumatic and musculoskeletal diseases(RMD). The causes of fatigue are not well understood, and it is likely that they vary between people and over time.

8 Dec 2023

Women undergoing chemotherapy may not benefit from common fertility protection drug

A new study from Karolinska Institutet in Sweden has found no evidence that a common drug used to protect the ovaries of women undergoing chemotherapy increases their chances of having children after cancer treatment.

8 Dec 2023

Small molecule drug shows promise as potential new treatment for multiple sclerosis

CAMH-led pre-clinical studies using a small molecule drug have shown promise as a potential new treatment for multiple sclerosis (MS). The results have been published today in the journal Science Advances.

8 Dec 2023

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

A team from the Technical University of Munich (TUM) has decoded the factor that makes T cell lymphomas grow comparatively rapidly: A missing "emergency shut-off switch" results in the lymphomas processing particularly large amounts of sugar and triggers other processes as well.

8 Dec 2023

Closing the gender gap in HIV treatment could slash infection rates in Uganda

A study looking at 15 years of HIV transmission and suppression in Uganda reveals how closing gender gaps in treatment could slash infection rates.

8 Dec 2023

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Study examines the efficacy of anastrozole in preventing breast cancer in postmenopausal women at high risk, focusing on the role of baseline estradiol levels and their impact on treatment outcomes.

7 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

Paracetamol and ibuprofen equally effective for tension-type headaches, study reveals

A systematic review and meta-analysis in Scientific Reports finds no significant difference between paracetamol and ibuprofen in treating episodic tension-type headaches, suggesting both as viable options for pain relief.

7 Dec 2023

Researchers discover how bexmarilimab activates immune cells against tumors

Researchers at the University of Turku, Finland, have uncovered how the new bexmarilimab therapy alters the function of immune cells so that they can infiltrate the tumor in cancer patients who do not respond to any other current therapies.

7 Dec 2023

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023

Psychotria malayana Jack leaf extract could effectively treat diabetes with lower toxicity

Psychotria malayana Jack leaf extract (OE) to evaluate its anti-diabetic, anti-inflammatory, and antioxidant properties.

7 Dec 2023

Thalamus-targeted deep brain stimulation improves cognition in brain injury patients

Study shows that deep brain stimulation (DBS) of the central lateral thalamic nuclei and medial dorsal tegmental tract improves executive function in patients with moderate-severe traumatic brain injury, offering a potential new treatment approach.

6 Dec 2023

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

6 Dec 2023

New drug combo fights breast cancer with brain metastases

A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results from the HER2CLIMB-02 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

Music could hold the key to developing effective mental health interventions

How human beings respond to music and the biological underpinnings of this response.

6 Dec 2023

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Researchers assessed ethnic and racial differences in novel hormonal therapy (NHT) use among advanced prostate cancer (PCa) patients.

6 Dec 2023

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms.

5 Dec 2023

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

The safety, efficacy, and immunogenicity of a mRNA-based vaccine.

5 Dec 2023

Efficacy News and Research

Small molecule applications of process Raman spectroscopy

New insights into how anti-obesity drugs could help prevent kidney disease

New guidelines offer hope for fatigue management in people with inflammatory RMD

Women undergoing chemotherapy may not benefit from common fertility protection drug

Small molecule drug shows promise as potential new treatment for multiple sclerosis

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

Closing the gender gap in HIV treatment could slash infection rates in Uganda

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Paracetamol and ibuprofen equally effective for tension-type headaches, study reveals

Researchers discover how bexmarilimab activates immune cells against tumors

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Psychotria malayana Jack leaf extract could effectively treat diabetes with lower toxicity

Thalamus-targeted deep brain stimulation improves cognition in brain injury patients

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

New drug combo fights breast cancer with brain metastases

Music could hold the key to developing effective mental health interventions

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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