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Acute kidney injury in intensive-care COVID-19 patients

71 patients with severe lung injury were admitted to four intensive care units at Bordeaux University Hospital and their data were collected and evaluated over a period of six weeks (March/April 2020). AKI was defined using KDIGO criteria and ADQI according to the Acute Disease Quality Initiative (ADQI) 16 workgroup.

8 Jun 2020

Study identifies potential biomarker for prescreening donor's stem cells

A new study released today in STEM CELLS addresses a significant problem that has been confronting human mesenchymal stem cells (hMSCs) therapy.

8 Jun 2020

Study uncovers link between psoriasis and joint disease

A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure.

8 Jun 2020

Gene expression may be a decisive factor for controlling possible comorbidities

A study led by the Barcelona Supercomputing Center, in which the Universitat de València participates, concludes that the specific characteristics of each patient, such as gene expression, may be a decisive factor in the development of clinical strategies aimed at addressing and controlling possible comorbidities.

8 Jun 2020

Scientists find way to prevent warmed-up vaccines from degrading

Vaccines are notoriously difficult to transport to remote or dangerous places, as they spoil when not refrigerated.

8 Jun 2020

Rapid changes to health system spurred by COVID might be here to stay

The U.S. health care system is famously resistant to government-imposed change. It took decades to create Medicare and Medicaid, mostly due to opposition from the medical-industrial complex. Then it was nearly another half-century before the passage of the Affordable Care Act.

8 Jun 2020

Genetic studies analyze genome-wide set of genetic variants in different individuals

Genome-wide association studies (GWAS) analyze a genome-wide set of genetic variants in different individuals to see if any are associated with a trait or disease.

8 Jun 2020

Majority of hospitalized patients with advanced cancer have functional impairment

New research from Mass General Cancer Center, published in the June 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network, found 40.2% of hospitalized patients with advanced, incurable cancer were functionally impaired at the time of admission, meaning they needed assistance with activities of daily living (ADLs) like walking, bathing, getting dressed, or other routine tasks. Patients with functional impairment also had higher rates of pain, depression, and anxiety, and were more likely to have longer hospital stays and worse survival.

8 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020

Using microorganisms and their enzymes to produce minor ginsenosides

In this review article the author Almando Geraldi from the Universitas Airlangga, Indonesia considers the advances in the production of minor ginsenosides using microorganisms and their enzymes.

5 Jun 2020

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

This spring marked a seismic shift for digestive and liver disease research at the Medical University of South Carolina with the award of more than $16.5 million in National Institutes of Health funding to open two new tightly integrated centers.

5 Jun 2020

Creating hair-bearing human skin becomes a reality

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin--hair, nerves, and fat.

5 Jun 2020

UTHSC researchers receive NIH award for opioid addiction studies

A team of University of Tennessee Health Science Center researchers in the College of Medicine recently received a National Institutes of Health award to study how genetic differences may explain why some people are more susceptible to opioid addiction than others.

5 Jun 2020

New educational program improves bike helmet use by urban children

To reduce the number of traumatic brain injuries in children, a team of health care professionals at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health is urging emergency room physicians to help ensure that youngsters are thoroughly educated on the proper use of bike helmets, especially in urban environments where most severe head injuries occur.

5 Jun 2020

Volcanic glass spray effective in controlling mosquitoes

An indoor residual spray made by combining a type of volcanic glass with water showed effective control of mosquitoes that carry malaria, according to a new study.

5 Jun 2020

NMDA receptors play key role in sleep deficits that accompany psychiatric disorders

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in electroencephalograms (EEG) of people with schizophrenia. The article was published in the Schizophrenia Research on June 5.

5 Jun 2020

Tear-gassing protesters during an infectious outbreak ‘a recipe for disaster’

In nationwide demonstrations sparked by the killing of George Floyd in police custody, protesters have been frequently pepper-sprayed or enveloped in clouds of tear gas.

5 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

New guidance for healthcare providers caring for hospitalized COVID-19 patients with diabetes

The COVID-19 pandemic presents new challenges for clinicians caring for infected patients with diabetes, according to new guidance published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Jun 2020