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Researchers explore the development of mRNA vaccines against respiratory syncytial virus

Recently, researchers discussed the development of messenger ribonucleic acid (mRNA) vaccines against the respiratory syncytial virus (RSV).

17 Oct 2022

Scientists use enhanced environmental surveillance for poliovirus type 2 detection in London sewage samples

In a new study, researchers investigated molecular properties of type 2 poliovirus (PV) isolates obtained from sewage samples (SS) to detect PV transmission in communities.

17 Oct 2022

Study uses whole genome sequencing to trace SARS-CoV-2 transmission within Welsh hospital

In a new study, researchers used whole genome sequencing to examine the patients-to-staff, staff-to-patients, and staff-to-staff transmission of SARS-CoV-2 in hospitals in Wales.

17 Oct 2022

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

In silico studies assess the binding efficacy of phytoconstituents against active sites of SARS-CoV-2.

16 Oct 2022

New findings point to specific genes linked with increased risk of frozen shoulder

Frozen shoulder, or adhesive capsulitis, is a common cause of shoulder pain and immobility. New findings point to specific genes associated with an increased risk of this condition, reports The Journal of Bone & Joint Surgery.

14 Oct 2022

Researchers identify a previously unknown mitochondrial disease in identical twins

In a set of identical twins, investigators led by researchers at Massachusetts General Hospital (MGH) and Children's Hospital Philadelphia (CHOP) have identified a mitochondrial disease not previously reported.

14 Oct 2022

Study describes the first SARS-CoV-2 Deltacron recombinant case identified in Brazil

Researchers demonstrated the parallel evolution of the SARS-CoV-2 Deltacron variant.

14 Oct 2022

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a leading infectious threat to public health worldwide.

13 Oct 2022

DTU researchers create a new tool in the fight against resistant bacteria

According to the WHO, antibiotic resistance is one of the biggest threats to public health. DTU researchers have created a new tool in the fight against resistant bacteria that, based on 214,000 microbiome samples, can create an overview of the problem across countries, people and environments.

13 Oct 2022

Largest academic collaboration aims to transform the treatment for pediatric cancers

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children's Research Hospital today announced the largest academic collaboration of its kind to transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into better treatments.

13 Oct 2022

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

In a new study, researchers visualized the mechanism of action and inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 13 (NSP13) at high spatio-temporal resolution.

13 Oct 2022

UQ-led study analyzes genetic variants that influence height

Children's growth will be easier to assess following a University of Queensland-led study analyzing the genetic variants that influence height.

12 Oct 2022

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers developed a RT-qPCR system to identify SARS-CoV-2 Omicron variants of concern.

12 Oct 2022

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Scientists have identified a handful of gene mutations that cause or contribute to the onset of Alzheimer's disease.

11 Oct 2022

Two new studies help improve the understanding of ovarian cancer

Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women's tumors do not respond to therapy.

11 Oct 2022

Mismatches in the primer and probe sequences of current Monkeypox virus diagnostic assays require rectification to improve detection accuracy

Researchers analyzed the primer and probe sequences of the United States Centers for Disease Control and Prevention (CDC) recommended monkeypox virus (MPXV) generic real-time polymerase chain reaction (PCR) assays.

11 Oct 2022

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins.

11 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

A new paper reviews current knowledge of RdRp inhibitors that could be developed further to provide broadly effective antivirals against SARS-CoV-2 in particular and CoVs in general.

10 Oct 2022

Zinc could improve the brain defects caused by rare genetic disorder

Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene.

10 Oct 2022

Genome News and Research

Researchers explore the development of mRNA vaccines against respiratory syncytial virus

Scientists use enhanced environmental surveillance for poliovirus type 2 detection in London sewage samples

Study uses whole genome sequencing to trace SARS-CoV-2 transmission within Welsh hospital

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

New findings point to specific genes linked with increased risk of frozen shoulder

Researchers identify a previously unknown mitochondrial disease in identical twins

Study describes the first SARS-CoV-2 Deltacron recombinant case identified in Brazil

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

DTU researchers create a new tool in the fight against resistant bacteria

Largest academic collaboration aims to transform the treatment for pediatric cancers

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

UQ-led study analyzes genetic variants that influence height

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Two new studies help improve the understanding of ovarian cancer

Mismatches in the primer and probe sequences of current Monkeypox virus diagnostic assays require rectification to improve detection accuracy

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

Zinc could improve the brain defects caused by rare genetic disorder

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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