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Study reveals dopamine sends precise signals rather than broad brainwide messages

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed.

12 Jul 2025

Social media analysis reveals emotional burden of children with multiple health conditions

Children with multiple long-term health issues undergo severe emotional stress at the same time as they are trying to cope with the physical challenges of their condition, a study has found.

12 Jul 2025

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they experienced positive outcomes that support use of targeted radiation in the future for such patients.

12 Jul 2025

Prefrontal cortex RNA drives female-specific brain resilience to depression

A traditionally overlooked type of RNA plays an important role in promoting resilience to depression-but only in females.

12 Jul 2025

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, represents a spectrum of liver disorders ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis.

12 Jul 2025

Osteoblast estrogen receptor signaling found essential for bone integrity

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects bone health.

12 Jul 2025

Hepatitis C treatment gaps persist for children and new mothers

As the opioid epidemic has worsened in the United States, prevalence of hepatitis C has also increased. Hepatitis C is a bloodborne virus that damages the liver.

11 Jul 2025

New analysis reveals widespread progression of CKM syndrome across the U.S.

One in three adults in the U.S. has three or more risk factors for a newly recognized but increasingly common condition: cardiovascular-kidney-metabolic (CKM) syndrome.

11 Jul 2025

Hollywood myths about heart attacks may be putting lives at risk

Hollywood has shaped how many people imagine a heart attack-someone clutching their chest and collapsing dramatically. But those portrayals are misleading and shouldn't be expected, says Ann Eckhardt, a nursing professor and researcher at The University of Texas at Arlington.

11 Jul 2025

Genetic links between type 2 diabetes and subcortical brain structure revealed

Recently, the team led by Chief Physician Quan Zhang and Associate Professor Feng Liu at Tianjin Medical University General Hospital systematically evaluated the genetic associations between type 2 diabetes mellitus and subcortical brain structures using large-scale genome-wide association summary statistics and advanced statistical genetic methods.

11 Jul 2025

Egr-1 gene identified as crucial regulator of regulatory T cells in multiple sclerosis

Autoimmune diseases, such as multiple sclerosis (MS), inflammatory bowel disease (IBD), and rheumatoid arthritis (RA), affect millions of people worldwide.

11 Jul 2025

Maltreatment in early childhood tied to lasting behavioral challenges

Childhood maltreatment leaves deep and lasting marks that have far-reaching consequences, extending beyond immediate trauma and affecting survivors in ways that are often invisible and misunderstood.

11 Jul 2025

Autistic and neurotypical adults process body parts similarly in the brain

Autism spectrum disorder (ASD), a neurodevelopmental condition, is often associated with difficulties in social communication and repetitive behavior.

11 Jul 2025

Study confirms high survival rates for men with low-risk prostate cancer

New research in the July 2025 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that for people diagnosed with nonmetastatic low-risk prostate cancer later in life, and treated according to NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines), 90% were likely to survive their cancer for their remaining life-expectancy.

11 Jul 2025

Ultrasound technique enhances decision making for reduced fetal movement

It can be difficult to decide whether to expedite birth when a woman in the final stage of pregnancy perceives less fetal movements.

11 Jul 2025

New chemotherapy regimen improves fertility outcomes in young Hodgkin's lymphoma patients

Young patients with advanced Hodgkin's lymphoma, a cancer of the lymphatic system, now have a better chance of having their own children after treatment.

10 Jul 2025

Distressed births linked to mental and physical problems later in life

A research study crafted by two University of Miami Patti and Allan Herbert Business School professors establishes a strong correlation between distressed births and experiencing mental and physical problems later in life.

10 Jul 2025

Mitochondria and peroxisomes work together to defend against cell damage

An international team led by researchers at The Hospital for Sick Children (SickKids), Princess Margaret Cancer Centre, Dalhousie University, the University of Exeter (UK) and the Medical University of Vienna (Austria) has uncovered a surprising way compartments within cells work together to defend themselves against oxidative stress, a finding that could shift how we understand age-associated conditions such as diabetes and neurodegenerative diseases.

10 Jul 2025

KFF Health News' 'What the Health?': Digesting Trump’s big budget law

As he had wanted, President Donald Trump signed his big budget bill into a big budget law in a White House ceremony on July 4, cementing, among other things, billions of dollars in cuts to health programs such as Medicaid.

10 Jul 2025

Updated NeoVax cancer vaccine shows improved immune response in melanoma trial

Results of a Dana-Farber Cancer Institute-initiated phase 1 clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine called NeoVaxMI is safe, feasible, and improves the vaccine-specific immune response compared to previous trials of the platform.

10 Jul 2025