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Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced positive topline safety and tolerability results from a Phase 1b clinical trial of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy.

10 Feb 2015

Mercury associated with autoimmunity among women of childbearing age

One of the greatest risk factors for autoimmunity among women of childbearing age may be associated with exposure to mercury such as through seafood, a new University of Michigan study says.

10 Feb 2015

Researchers document pathological progress of multiple sclerosis

The Centre for Brain Research at the MedUni Vienna is regarded as a world leader in researching the mechanisms involved with multiple sclerosis (MS). Now, in a paper published in the highly respected journal Lancet Neurology, an international team of researchers from Edinburgh, Cleveland and Vienna, under the leadership of Hans Lassmann, Head of the Department of Neuroimmunology at the MedUni Vienna, has for the first time documented the pathological progress of the disease from its early to late stage and also shown that inflammatory and neurodegenerative processes have a role to play.

9 Feb 2015

Alzheimer's brains commonly have many neurons with more DNA and genomic copies of APP gene

Scientists at The Scripps Research Institute have found diverse genomic changes in single neurons from the brains of Alzheimer's patients, pointing to an unexpected factor that may underpin the most common form of the disease.

5 Feb 2015

Diplomat to dispense FDA-approved IBRANCE (palbociclib) to treat metastatic breast cancer

Diplomat Pharmacy, Inc., the nation's largest independent specialty pharmacy, announced today it will dispense Pfizer's new breakthrough medication, IBRANCE (palbociclib), starting tomorrow, Feb. 5.

4 Feb 2015

Can-Fite BioPharma completes patient enrollment in CF101 Phase II/III psoriasis trial

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today that all patients enrolled in its Phase II/III psoriasis trial for the Company's drug candidate CF101 have completed the study's 32 week treatment protocol.

4 Feb 2015

EyeBrain raises €1.3 million ($1.47 million) through crowdfunding

EyeBrain, a company that develops markers of cerebral function for neurological and psychiatric disorders and diseases, today announces the conclusion of a new round of funding. A total of €1.3 million ($1.47 million) has been raised with the support of EyeBrain’s shareholders, the Fonds Régional de Co-Investissement d’Ile-de-France (FRCI, regional joint investment fund for the Ile-de-France or Greater Paris area) and the Anaxago crowdfunding platform.

4 Feb 2015

Accelerated Cure Project for MS launches nationwide initiative to fuel multiple sclerosis research

The Accelerated Cure Project for Multiple Sclerosis today launches iConquerMS, the nationwide initiative by and for individuals living with multiple sclerosis who recognize the power of their health data and insights and want to harness that power to fuel research.

3 Feb 2015

Findings may lay foundation for treatment of neurodegenerative diseases

This story starts in 1955, upon the death of Albert Einstein, when the pathologist charged with performing the famous scientist's autopsy stole his brain.

3 Feb 2015

People's perceptions of cost of drug may affect how much they benefit from it

People's perceptions of the cost of a drug may affect how much they benefit from the drug, even when they are receiving only a placebo, according to a new study of people with Parkinson's disease published in the January 28, 2015 online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Feb 2015

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.

31 Jan 2015

Promising results for stem cell therapy in MS

Preliminary findings suggest that nonmyeloablative haematopoietic stem cell transplantation may arrest, or even reverse, the progress of disease among patients with relapsing–remitting multiple sclerosis.

28 Jan 2015

Scientists identify new molecular pathway that controls axonal degeneration following injury

Axons connect neurons with each other to form the neural networks that underpin the vital functions of perception, motility, cognition, and memory. In many neurodegenerative disorders, from traumatic injury or toxic damage to diseases such as Alzheimer's or Parkinson's disease, axonal degeneration represents an essential pathological feature.

23 Jan 2015

New discovery may help doctors develop better treatments for brain, spinal cord injuries

In a discovery that could dramatically affect the treatment of brain and spinal cord injuries, researchers have identified a previously unknown, beneficial immune response that occurs after injury to the central nervous system.

23 Jan 2015

Scientists identify gene that helps regulate development of central nervous system

Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.

23 Jan 2015

USC neuroscientists find potential prevention for Alzheimer's disease

University of Southern California neuroscientists may have unlocked another puzzle to preventing risks that can lead to Alzheimer's disease. Researchers at Keck Medicine of USC used high-resolution imaging of the living human brain to show for the first time that the brain's protective blood barrier becomes leaky with age, starting at the hippocampus, a critical learning and memory center that is damaged by Alzheimer's disease.

22 Jan 2015

New article provides insight into cognitive fatigue in people with multiple sclerosis

Kessler Foundation researchers have authored a new article that provides insight into the factors that contribute to cognitive fatigue in individuals with multiple sclerosis (MS). The article, "Subjective cognitive fatigue in MS depends on task length," was epublished ahead of print on October 27 in Frontiers in Neurology.

22 Jan 2015

Cornell scientists develop new computational method to identify functional human genome

Striving to unravel and comprehend DNA's biological significance, Cornell University scientists have created a new computational method that can identify positions in the human genome that play a role in the proper functioning of cells, according to a report published Jan. 19 in the journal Nature Genetics.

22 Jan 2015

Two new drug compounds appear to be effective in treating endometriosis

Two new drug compounds - one of which has already proven useful in a mouse model of multiple sclerosis - appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine.

22 Jan 2015

Stomach ulcer bug H. pylori may reduce risk of developing multiple sclerosis

A West Australian team has found evidence that the stomach ulcer bacterium, Helicobacter pylori, is associated with a lower risk of multiple sclerosis (MS), bolstering evidence for the role of the ‘hygiene hypothesis’ in autoimmune disorders.

21 Jan 2015

Sclerosis News and Research

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Mercury associated with autoimmunity among women of childbearing age

Researchers document pathological progress of multiple sclerosis

Alzheimer's brains commonly have many neurons with more DNA and genomic copies of APP gene

Diplomat to dispense FDA-approved IBRANCE (palbociclib) to treat metastatic breast cancer

Can-Fite BioPharma completes patient enrollment in CF101 Phase II/III psoriasis trial

EyeBrain raises €1.3 million ($1.47 million) through crowdfunding

Accelerated Cure Project for MS launches nationwide initiative to fuel multiple sclerosis research

Findings may lay foundation for treatment of neurodegenerative diseases

People's perceptions of cost of drug may affect how much they benefit from it

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

Promising results for stem cell therapy in MS

Scientists identify new molecular pathway that controls axonal degeneration following injury

New discovery may help doctors develop better treatments for brain, spinal cord injuries

Scientists identify gene that helps regulate development of central nervous system

USC neuroscientists find potential prevention for Alzheimer's disease

New article provides insight into cognitive fatigue in people with multiple sclerosis

Cornell scientists develop new computational method to identify functional human genome

Two new drug compounds appear to be effective in treating endometriosis

Stomach ulcer bug H. pylori may reduce risk of developing multiple sclerosis

Industry Focus eBook - Cell biology (5th edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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