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CDC, State Department, World Bank should lead fight against fake, substandard TB drugs

"Thanks to billions of dollars spent on diagnosis and treatment of tuberculosis (TB) over the past decade, deaths and infections are slowly declining," but "fake and poorly made antibiotics are being widely used to treat tuberculosis," according to a study "to be published Tuesday in the International Journal of Tuberculosis and Lung Disease," Roger Bate, a resident scholar at the American Enterprise Institute and an author of the study, writes in a New York Times opinion piece.

6 Feb 2013

Study findings suggest physical and pharmacological solutions for human stroke victims

Johns Hopkins researchers have found that mice can recover from physically debilitating strokes that damage the primary motor cortex, the region of the brain that controls most movement in the body, if the rodents are quickly subjected to physical conditioning that rapidly "rewires" a different part of the brain to take over lost function.

6 Feb 2013

Three NIH-sponsored influenza trials begin to enroll volunteers

Three clinical trials that seek to find more effective treatments for influenza are enrolling volunteers with influenza at the National Institutes of Health's Clinical Center in Bethesda, Md., and at several dozen other domestic and international sites.

6 Feb 2013

Verastem commences VS-6063 plus paclitaxel Phase 1/1b trial in advanced ovarian cancer

Verastem, Inc., a clinical-stage biopharmaceutical company focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced the initiation of a Phase 1/1b trial of VS-6063 in combination with paclitaxel for the treatment of advanced ovarian cancer.

5 Feb 2013

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme "soluble adenylyl cyclase" that produces the second messenger molecule cAMP.

5 Feb 2013

Viewpoints: Sen. Hatch's prescription for safeguarding entitlements; Medicare crackdown on CVS drug program; JFK's mental health vision failing

American families are used to working with dollar amounts starting with hundreds and thousands. But the fiscal situation of our country requires us to act in terms of billions and trillions. ... Unfortunately, waiting until the last minute to stop a crisis has become standard operating procedure in Washington. But that isn't how we should be tackling our debt or safeguarding Medicare and Medicaid.

5 Feb 2013

Restricting gifts in medical school influences future prescribing behavior

US physicians who attended a medical school with a policy restricting acceptance of gifts from pharmaceutical companies are less likely to prescribe newly marketed drugs than physicians who were not exposed to such restrictions during training, according to research published in the BMJ.

5 Feb 2013

Location of altered brain metabolite levels found in bipolar I patients

Bipolar I disorder patients have increased phospholipid levels in the thalami and increased N-acetyl-aspartate levels in the left hippocampus compared with healthy individuals, a team of investigators has discovered.

5 Feb 2013

GLP-1 receptor agonists associated with reduced BMI in adolescents with severe obesity

Preliminary evidence from a clinical trial suggests that treatment with glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced body mass index and body weight in adolescents with severe obesity, according to a report published Online First by JAMA Pediatrics, a JAMA Network publication.

5 Feb 2013

Results from Merck’s Vorinostat phase 1 trial on lymphoma

Patients whose aggressive lymphomas have relapsed or failed to respond to the current front-line chemotherapy regimen now have an effective second line of attack against their disease.

5 Feb 2013

Orphan, St George's sign licensing agreement to develop new therapies for metabolic disorders

St George's, University of London has signed an exclusive worldwide licensing agreement with rare-disease research-and-development firm Orphan Technologies Ltd to develop new therapies for deadly metabolic disorders.

5 Feb 2013

UPCI researchers uncover new technique to stop growth of cancer cells

University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

5 Feb 2013

An Introduction to the LV200 Bioluminescence Microscope

News-Medical speaks to Robert Schmalzigaug to explore the field of bioluminescence imaging and the applications of the LV200 microscope.

From Evident Corporation - Life Sciences 5 Feb 2013

CMS releases overdue final 'Sunshine Act' rule on payments to physicians

Under the Physician Payments Sunshine Act, financial relationships that drug and device makers have with doctors must be disclosed.

5 Feb 2013

Scientists identify specific cellular events that appear key to lupus

A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The findings suggest that blocking this pathway in lupus-triggering cells could be a potent weapon against the disease.

5 Feb 2013

Accumulation of passenger mutations can slow or even halt tumor growth

A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits such as uncontrolled growth. Cancer biologists have largely ignored the other mutations, believing they had little or no impact on cancer progression.

5 Feb 2013

USPTO issues patent to KAHR-101 for treatment of cancers, arthritis and MS

Hadasit Bio-Holdings Ltd., a publicly traded portfolio of biotech companies, based on intellectual property developed and owned by Hadassah University Hospital, Israel's foremost medical research center, today announced that its portfolio company, KAHR Medical Ltd., was granted a U.S. patent approval (U.S. Patent No. 8329657).

5 Feb 2013

Drugs News and Research

CDC, State Department, World Bank should lead fight against fake, substandard TB drugs

Study findings suggest physical and pharmacological solutions for human stroke victims

Three NIH-sponsored influenza trials begin to enroll volunteers

Verastem commences VS-6063 plus paclitaxel Phase 1/1b trial in advanced ovarian cancer

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

Viewpoints: Sen. Hatch's prescription for safeguarding entitlements; Medicare crackdown on CVS drug program; JFK's mental health vision failing

Restricting gifts in medical school influences future prescribing behavior

Location of altered brain metabolite levels found in bipolar I patients

GLP-1 receptor agonists associated with reduced BMI in adolescents with severe obesity

Results from Merck’s Vorinostat phase 1 trial on lymphoma

Orphan, St George's sign licensing agreement to develop new therapies for metabolic disorders

UPCI researchers uncover new technique to stop growth of cancer cells

An Introduction to the LV200 Bioluminescence Microscope

CMS releases overdue final 'Sunshine Act' rule on payments to physicians

Scientists identify specific cellular events that appear key to lupus

Accumulation of passenger mutations can slow or even halt tumor growth

USPTO issues patent to KAHR-101 for treatment of cancers, arthritis and MS

AIBioTech announces implementation of L-asparaginase activity assay for pediatric ALL

Agilent launches new application compendiums on designer drug testing and toxicology of oral fluids

Sun Pharma receives FDA approval for generic Doxil

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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