Cell Death News and Research

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New dye more effective in detecting, measuring cardiolipin in cell membranes

A team that includes Dartmouth College researchers has discovered a new way to detect cardiolipin, a key indicator of heart diseases and some genetic disorders.

16 Jan 2014

Research findings may offer new way to treat prion diseases

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

16 Jan 2014

Study shows direct link between metabolism in brain cells and ability to signal information

A new study by scientists at McGill University and the University of Zurich shows a direct link between metabolism in brain cells and their ability to signal information. The research may explain why the seizures of many epilepsy patients can be controlled by a specially formulated diet.

16 Jan 2014

New gene therapy restores some sight in people born with inherited form of blindness

A new gene therapy has restored some sight in people born with an inherited, progressive form of blindness. The technique replaces a defective gene in the eye with a normal working copy of the gene using a single injection.

16 Jan 2014

Study suggests effective way to counter influenza infections

McGill researchers, led by Dr. Maya Saleh of the Department of Medicine, have identified an enzyme, cIAP2 that helps the lungs protect themselves from the flu by giving them the ability to resist tissue damage. "It's a discovery that offers exciting new avenues for controlling influenza, since until now attempts to target the virus itself have proven challenging, especially in the face of emerging new strains of the virus," says Saleh, who is also a researcher at the Research Institute of the McGill University Health Centre.

15 Jan 2014

Research reveals new therapy for preventing production of sphingolipids by lymphoma cells

Christopher Parsons, MD, Director of the HIV Malignancies Program at LSU Health Sciences Center New Orleans, is the senior author of a paper that is the first to report that specialized fat (lipid) molecules, called sphingolipids, play a key role in the survival of aggressive lymphomas caused by viruses.

15 Jan 2014

Study: HIV-specific poison kills persisting HIV-infected cells during antiretroviral therapy

A team including University of North Carolina and NIH scientists has demonstrated in a mouse model that an HIV-specific poison can kill cells in which the virus is actively reproducing despite antiretroviral therapy.

10 Jan 2014

High presence of bacteria linked to early water breaking during pregnancy

A high presence of bacteria at the site where fetal membranes rupture may be the key to understanding why some pregnant women experience their "water breaking" prematurely, researchers at Duke Medicine report.

9 Jan 2014

Hebrew University research could lead to efficient and fast-acting antidepressant drugs

The World health Organization calls depression "the leading cause of disability worldwide," causing more years of disability than cancer, HIV/AIDS, and cardiovascular and respiratory diseases combined.

8 Jan 2014

JDRF joins with Brehm Center to investigate about lost beta cell function in type 1 diabetes

JDRF announced today the funding of an approximately $1 million collaboration with the University of Michigan's Brehm Center and the Brehm Coalition to evaluate a new hypothesis on why beta cells lose their ability to produce insulin, resulting in a diagnosis of type 1 diabetes (T1D).

8 Jan 2014

Horizon, AstraZeneca partner to explore oncology-relevant genotypes to identify novel drug targets

Horizon Discovery and AstraZeneca have entered into a research, collaboration and license agreement to explore a range of oncology-relevant genotypes with the aim of identifying and validating a number of novel drug targets. This deal is the second collaboration between AstraZeneca and Horizon, and follows the announcement in April 2013 of an oncology discovery program to explore Horizon's first-in-class kinase target program, HD-001.

7 Jan 2014

Cancer cells less likely to develop resistance when multiple drugs delivered simultaneously

Researchers have developed a technique for creating nanoparticles that carry two different cancer-killing drugs into the body and deliver those drugs to separate parts of the cancer cell where they will be most effective. The technique was developed by researchers at North Carolina State University and the University of North Carolina at Chapel Hill.

7 Jan 2014

Researchers find inhibition of basic cellular process that contributes to schizophrenia

Surprisingly little is known about schizophrenia. It was only recognized as a medical condition in the past few decades, and its exact causes remain unclear. Since there is no objective test for schizophrenia, its diagnosis is based on an assortment of reported symptoms.

30 Dec 2013

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

A deadly, rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved in its growth, UT Southwestern Medical Center researchers report.

27 Dec 2013

Research findings reveal how immune system responds to respiratory viral infections

An antibody that blocks a component of a key signaling pathway in the respiratory airways could help the immune system rid the body of the influenza virus, a new study suggests. The findings, from a team at The Research Institute at Nationwide Children's Hospital, not only offer a new approach to treating the flu, but also add new information about how the immune system responds to respiratory viral infections.

24 Dec 2013

Manipulating epigenetic mechanism may promote cell death in pediatric brain cancer

Researchers at the Federal University of Rio Grande do Sul, the university hospital (Hospital de Cl-nicas de Porto Alegre, HCPA) and the Children's Cancer Institute (Instituto do C-ncer Infantil do Rio Grande do Sul, ICI-RS) in Porto Alegre, Brazil, have shown that manipulating an epigenetic mechanism, which regulates gene expression, may promote cell death and favor maturation towards less malignant-prone phenotypes in pediatric brain cancer cell lines.

22 Dec 2013

Researchers discover new way to make chemotherapy treatment effective for pancreatic cancer patients

Scientists from The University of Manchester - part of Manchester Cancer Research Centre believe they have discovered a new way to make chemotherapy treatment more effective for pancreatic cancer patients.

From The University of Manchester 21 Dec 2013

Study reveals that K-Ras gene mutations behave in ways that subvert normal mechanisms of cell death

Cells with a mutation in the gene called K-Ras—found in close to 30 percent of all cancers, but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung cancer—behave in ways that subvert the normal mechanisms of cell death, according to a cell-culture study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah.

20 Dec 2013

Study finds milk serves as protective carrier of bioactive molecules

Polyphenols found in tea manifest anti-cancer effects but their use is limited by poor bioavailability and disagreeable taste. A new study in the Journal of Dairy Science- finds that when epigallocatechin gallate (EGCG), the major extractable polyphenol in green tea and the most biologically active, when diluted in skim milk or other milk complexes remains bioactive and continues to reduce colon cancer cell proliferation in culture at concentrations higher than 0.03 mg of EGCG/mL.

20 Dec 2013

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

Obesity, alcoholism, and chronic hepatitis all increase the risk of getting liver cancer, which is the third leading cause of cancer death worldwide. Obesity in particular is driving a significant increase in liver cancer in the United States.

20 Dec 2013

Cell Death News and Research

New dye more effective in detecting, measuring cardiolipin in cell membranes

Research findings may offer new way to treat prion diseases

Study shows direct link between metabolism in brain cells and ability to signal information

New gene therapy restores some sight in people born with inherited form of blindness

Study suggests effective way to counter influenza infections

Research reveals new therapy for preventing production of sphingolipids by lymphoma cells

Study: HIV-specific poison kills persisting HIV-infected cells during antiretroviral therapy

High presence of bacteria linked to early water breaking during pregnancy

Hebrew University research could lead to efficient and fast-acting antidepressant drugs

JDRF joins with Brehm Center to investigate about lost beta cell function in type 1 diabetes

Horizon, AstraZeneca partner to explore oncology-relevant genotypes to identify novel drug targets

Cancer cells less likely to develop resistance when multiple drugs delivered simultaneously

Researchers find inhibition of basic cellular process that contributes to schizophrenia

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

Research findings reveal how immune system responds to respiratory viral infections

Manipulating epigenetic mechanism may promote cell death in pediatric brain cancer

Researchers discover new way to make chemotherapy treatment effective for pancreatic cancer patients

Study reveals that K-Ras gene mutations behave in ways that subvert normal mechanisms of cell death

Study finds milk serves as protective carrier of bioactive molecules

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

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