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NEI researchers create a high-resolution map of retinal cell chromatin contract points

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus.

7 Oct 2022

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

A well-functioning immune system is essential for protection against infections. However, with increasing age, the functioning of the immune system diminishes, which is also due to age-related damage in hematopoietic (blood) stem cells.

7 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Researchers demonstrated that the SARS-CoV-2 protein functions as a histone mimic to disrupt the epigenetic regulation of host cells.

7 Oct 2022

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Researchers explored the role of the ORF3c, a SARS-CoV-2 accessory protein not so extensively studied as yet.

7 Oct 2022

The magnitude and duration of the protective effect of prior infection and hybrid immunity against Omicron infection and severe disease

Researchers reviewed the duration and magnitude of the protective effect of previous SARS-CoV-2 infections and hybrid immunity against SARS-CoV-2 Omicron variant of concern infections and COVID-19 severity.

7 Oct 2022

Researchers identify a new gene implicated in rare lysosomal storage disorder

In a rare disease called mucolipidosis type II, people’s hearts and abdomens swell, and their bones grow malformed.

6 Oct 2022

Improved brain organoids provide cellular and molecular insights into autism

Whatever you do, don't call them "mini-brains," say University of Utah Health scientists. Regardless, the seed-sized organoids - which are grown in the lab from human cells - provide insights into the brain and uncover differences that may contribute to autism in some people.

6 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

Environmental surveillance of SARS-CoV-2 could predict COVID-19 cases

A new study reported that coronavirus disease 2019 (COVID-19) cases could be predicted by environmental surveillance.

6 Oct 2022

Can surveillance of SARS-CoV-2 be conducted through aircraft wastewater analysis?

Research investigates the behavior of air travelers, especially those who had flown during the pandemic.

6 Oct 2022

Stanford researchers create new technique for controlling protein production

Thanks to new RNA vaccines, we humans have been able to protect ourselves incredibly quickly from new viruses like SARS-CoV-2, the virus that causes COVID-19.

5 Oct 2022

Northwestern Medicine scientists discover new gene target for aggressive lung cancer

Northwestern Medicine scientists have identified and described a new gene that is responsible for activating an aggressive subtype of small-cell lung cancer, the P subtype, for which there is no current effective treatment.

5 Oct 2022

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Researchers demonstrated infection of human adipose tissue by SARS-CoV-2.

5 Oct 2022

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Researchers evaluated the messenger ribonucleic acid (mRNA)-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variant of concern infections and hospitalizations.

4 Oct 2022

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

In a new study, researchers performed a genomic study of confirmed Monkeypox virus (MPXV) cases diagnosed in Spain between 18 May and 14 July 2022.

4 Oct 2022

What are the challenges of COVID-19 vaccination and herd immunity?

A new study reviewed the challenges of coronavirus disease 2019 (COVID-19) vaccination and herd immunity.

4 Oct 2022

What are the genetic associations of stroke pathogenesis across ancestry groups?

In new research, researchers identified genetic associations of stroke pathogenesis.

4 Oct 2022

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

In a recent study posted to the medRxiv* preprint server, researchers in Canada assessed the effectiveness of protection elicited by the fourth dose of the coronavirus disease 2019 (COVID-19) mRNA vaccine.

4 Oct 2022

Sudden cardiac death risk can be determined by genetic score

A recent study published in the Journal of the American College of Cardiology found that a genome-wide polygenic score for coronary artery disease (GPSCAD) can predict sudden and/or arrhythmic death (SAD) risk in coronary artery disease (CAD) patients without severe systolic dysfunction.

3 Oct 2022

Genome News and Research

NEI researchers create a high-resolution map of retinal cell chromatin contract points

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

Researchers take new approach to studying the development of the human brain

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

The magnitude and duration of the protective effect of prior infection and hybrid immunity against Omicron infection and severe disease

Researchers identify a new gene implicated in rare lysosomal storage disorder

Improved brain organoids provide cellular and molecular insights into autism

What is the impact of monkeypox infection on the hemostatic system?

Environmental surveillance of SARS-CoV-2 could predict COVID-19 cases

Can surveillance of SARS-CoV-2 be conducted through aircraft wastewater analysis?

Stanford researchers create new technique for controlling protein production

Northwestern Medicine scientists discover new gene target for aggressive lung cancer

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

What are the challenges of COVID-19 vaccination and herd immunity?

What are the genetic associations of stroke pathogenesis across ancestry groups?

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

Sudden cardiac death risk can be determined by genetic score

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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