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Researchers discover three genes that may have contributed to evolution of large human brain

Three genes involved in nerve cell generation in the brain emerged roughly 3.5 million years ago and may have contributed to the rapid evolution of the large human brain, Howard Hughes Medical Institute (HHMI) Investigator David Haussler and colleagues report on May 31, 2018, in the journal Cell.

1 Jun 2018

Cancer cells can use lipid molecules as fuel for growth, shows study

Cancer cells can when the blood supply is low use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumor models by researchers at Karolinska Institutet in Sweden in a study published in Cell Metabolism.

1 Jun 2018

Hunger peptides sent through the brain's fluid cause appetite, shows study

A USC study shows the brain's plumbing system serves double duty, flushing waste and channeling a hunger molecule that tells you when you should eat.

1 Jun 2018

Study highlights complexity of the brain’s molecular response to cocaine use

A study in Biological Psychiatry has identified unique genetic changes in the brain's reward circuitry that are associated with cocaine use, including first-time use, withdrawal, and re-exposure to the drug after prolonged withdrawal.

31 May 2018

Study could open up new treatment approaches for neurodegenerative diseases

Cell biologists have deepened understanding of proteins associated with neurodegenerative diseases. The findings could open up new treatment approaches for disorders including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS), among others.

31 May 2018

Tiny ultrasound-powered nanorobots could offer safe, efficient way to detoxify biological fluids

Engineers at the University of California San Diego have developed tiny ultrasound-powered robots that can swim through blood, removing harmful bacteria along with the toxins they produce. These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids.

31 May 2018

Highly stable DNA origami nanostructures may pave way for a plethora of biomedical applications

The DNA origami technique is a widely used method for making complex, yet well-defined nanostructures, with applications in biophysics, molecular biology, as well as drug and enzyme delivery.

31 May 2018

Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

In most of the Western World, cancer is the primary cause of death in children over the age of one. Existing treatments for adult cancer patients are not particularly effective for children.

31 May 2018

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer - resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection.

31 May 2018

Scientists find enzyme that breaks down plasmalogens in Alzheimer's disease patients

Alzheimer's disease patients lose up to 60% of a component called plasmalogen from the membranes of the cells in their brains, but it's still not known how or why.

31 May 2018

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

A study conducted at the Massachusetts Institute of Technology has identified why the ApoE4 gene increases the risk of developing Alzheimer's disease, and why the ApoE3 gene reduces the risk.

31 May 2018

Weight gain may be the result of inefficient fat metabolism

Researchers from the Karolinska Institutet have shown that protracted weight gain can, in some cases, be attributed to a reduced ability to metabolise fat.

31 May 2018

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Mesoblast Limited today announced that it has entered into a partnership with Cartherics Pty Ltd to develop allogeneic ‘off-the-shelf’ CAR-T cells armed with multiple targeting receptors for use in solid cancers. Off the shelf CAR-T therapies have the potential to reduce costs dramatically and open up this very effective treatment to millions of cancer patients across the world.

31 May 2018

Scientists introduce combination approach to fight cancer

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor. In the journal Angewandte Chemie, scientists have introduced a new approach, in which two synergistic drug components are combined into a dimer.

31 May 2018

UTSA scientists explore stuttering and develop new technology to optimize brain function

A team of researchers at The University of Texas at San Antonio received a two-year, $387,000 grant, from the National Institutes of Health (NIH), to develop technology that will identify brain activity patterns that contribute to stuttering and use that technology to train people how to optimize brain functions.

31 May 2018

NIH study unravels how tularemia bacteria trick host cells to cause disease

Scientists from the National Institute of Allergy and Infectious Diseases--part of the National Institutes of Health--have unraveled the process by which the bacteria cause disease.

31 May 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

Our immune system's arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system.

30 May 2018

Cell News and Research

Researchers discover three genes that may have contributed to evolution of large human brain

Cancer cells can use lipid molecules as fuel for growth, shows study

Hunger peptides sent through the brain's fluid cause appetite, shows study

Study highlights complexity of the brain’s molecular response to cocaine use

Study could open up new treatment approaches for neurodegenerative diseases

Tiny ultrasound-powered nanorobots could offer safe, efficient way to detoxify biological fluids

Highly stable DNA origami nanostructures may pave way for a plethora of biomedical applications

Study: Cellular housekeeping can help mammals live longer and healthier

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Scientists find enzyme that breaks down plasmalogens in Alzheimer's disease patients

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

Weight gain may be the result of inefficient fat metabolism

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Scientists introduce combination approach to fight cancer

UTSA scientists explore stuttering and develop new technology to optimize brain function

NIH study unravels how tularemia bacteria trick host cells to cause disease

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

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