Cell Proliferation News and Research

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ING5 regulates metabolic reprogramming in lung cancer cells

Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes.

6 Jan 2025

Laser-textured stents offer promising solution for vascular diseases

The research team led by Dr. Hojeong Jeon and Dr. Hyung-Seop Han of the Biomaterials Research Center at the Korea Institute of Science and Technology (KIST, President Oh Sang-Rok), along with Dr. Indong Jun from KIST Europe, has developed a novel stent surface treatment technology using laser patterning.

26 Dec 2024

Scientists discover role of tumor stiffness in promoting cancer cell proliferation

In 2022 alone, over 20 million people were diagnosed with cancer, and nearly 10 million died from the disease, according to the World Health Organization.

20 Dec 2024

Long-term green tea catechins prevent aging-related cardiac dysfunction

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101284, discusses the effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I.

20 Dec 2024

Insights into LKB1's role in tumorigenesis

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101402, discusses insights into targeting LKB1 in tumorigenesis.

20 Dec 2024

Novel photosensitizer Ce6-GFFY shows promise for colorectal cancer therapy

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101441, discusses how Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy.

20 Dec 2024

Kaempferol boosts immune tolerance and fights allergies

Kaempferol's role in Treg development is linked to Aldh1a2 activation in dendritic cells, highlighting its potential in suppressing inflammation and allergies.

19 Dec 2024

Dinuclear platinum(II) complexes could offer a more targeted approach to treating prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men.

16 Dec 2024

Disrupting the circadian rhythm of glioblastoma slows tumor growth, study says

Virtually every cell in the human body has an internal clock. These clocks take their cues from a central clock in the brain. In a normal, biological process called synchrony, the central clock coordinates daily rhythms around the body, so that every cell and tissue recognizes the same external time of day.

13 Dec 2024

Study sheds light on Kif23's role in embryonic brain development and microcephaly

A team of researchers from Tohoku University, the National Center of Neurology and Psychiatry, and National Yang Ming Chiao Tung University has uncovered a novel molecular mechanism through which Kif23 (a motor protein belonging to the kinesin family) plays a vital role in embryonic brain development.

5 Dec 2024

Liver conversion of fructose fuels cancer growth by supplying lipids for tumor proliferation

This research highlights the indirect role of fructose in cancer, revealing how liver metabolism enhances tumor growth through lipid-mediated mechanisms.

5 Dec 2024

Cancer cells block T-cell activation, but new therapies restore immune defenses

Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment. Restoring balance through PGE2 inhibition and IFN-I enhancement could renew immune defenses and improve immunotherapy outcomes.

4 Dec 2024

Novel single-cell genomics analysis approach provides direct insights into cell cycle and proliferation

By inferring proliferation rates from single-cell genomics, SPRINTER enhances understanding of tumor evolution and identifies key clones in cancer progression.

4 Dec 2024

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

Findings indicate a serine/glycine-free diet can reduce colorectal cancer growth and enhance immune response, offering insights for immunotherapy strategies.

29 Nov 2024

Pcdh8 gene suppression critical for zebrafish notochord formation

Can a single protein-encoding gene determine whether a vertebrate embryo develops normally? Yes, according to Osaka Metropolitan University researchers, who found that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish.

21 Nov 2024

New CAR T-cell therapy shows promise against aggressive HER2+ breast cancer

One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Growth Factors Group, in collaboration with researchers of the Cancer Research Program of Hospital del Mar Research Institute (HMRI), Barcelona, have developed novel chimeric antigen receptor (CAR) T-cell therapy that can produce a potent antitumor response against p95HER2-expressing cells.

19 Nov 2024

Cell Proliferation News and Research

ING5 regulates metabolic reprogramming in lung cancer cells

Laser-textured stents offer promising solution for vascular diseases

Scientists discover role of tumor stiffness in promoting cancer cell proliferation

Long-term green tea catechins prevent aging-related cardiac dysfunction

Insights into LKB1's role in tumorigenesis

Novel photosensitizer Ce6-GFFY shows promise for colorectal cancer therapy

Kaempferol boosts immune tolerance and fights allergies

Dinuclear platinum(II) complexes could offer a more targeted approach to treating prostate cancer

Disrupting the circadian rhythm of glioblastoma slows tumor growth, study says

Study sheds light on Kif23's role in embryonic brain development and microcephaly

Liver conversion of fructose fuels cancer growth by supplying lipids for tumor proliferation

Cancer cells block T-cell activation, but new therapies restore immune defenses

Novel single-cell genomics analysis approach provides direct insights into cell cycle and proliferation

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

Pcdh8 gene suppression critical for zebrafish notochord formation

New CAR T-cell therapy shows promise against aggressive HER2+ breast cancer

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

Key kinase involved in cell division linked to abnormal blood vessel growth in genetic disorder

CRISPR technology reveals essential noncoding RNAs in the human genome

Multi-omics-based classification of gastrointestinal stromal tumors lays groundwork for precision treatment

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