Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers of the "Cell Biology and Physiology-LABRET" group of the University of Malaga (UMA), together with the Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), have described a new genetic skeletal disorder based on a precision medicine strategy.

22 Dec 2020

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Immune inflammatory mediators are critical in pathology, transplantation, and regenerative medicine, scientists report in The American Journal of Pathology

22 Dec 2020

COVID-19 genetic risk variants impact diverse immune cell types and severe disease manifestations

A team of researchers from UK and US used the DICE database and 3D cis-interactome maps to generate a list of target genes and immune cell types that are most affected by the genetic variants associated with COVID-19 severity.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Low testosterone can increase risk of severe COVID-19 in males

Researchers from the USA and Saudi Arabia describe the direct correlation between testosterone levels, inflammatory cytokines, disease progression, and worse outcomes in male COVID-19 patients.

4 Dec 2020

Intermediate embryonic stem cell type could lead to advances in regenerative medicine

A team led by UT Southwestern has derived a new "intermediate" embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.

4 Dec 2020

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

The onset of any physical exercise program causes muscle pain that can hinder movements as simple as getting up from a sofa. With time and a little persistence, the muscles become accustomed to the effort, developing more strength and endurance.

1 Dec 2020

Early, late stages of neurodegeneration are distinct, finds study

Rice University biochemists Michael Stern and James McNew have studied how neurodegeneration kills cells.

23 Nov 2020

SARS-CoV-2 causes a unique cytokine storm, study finds

A new study published on the preprint server medRxiv* in November 2020 reports some of the unique elements of COVID-19-induced CRS and how understanding these distinctive characteristics of the disease could help in formulating specific interventions and therapies.

18 Nov 2020

Study investigates possible link between sleep apnea and autoimmune diseases

New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies.

17 Nov 2020

Study sheds new light on the immune system response to COVID-19

A team of immunology experts from research organizations in Belgium and the UK has come together to apply their pioneering research methods to put individuals' COVID-19 responses under the microscope.

16 Nov 2020

Researchers to develop new optogenetic tools for biology and medicine

The European Research Council (ERC) is providing 10 million euros in funding for an interdisciplinary, collaborative project in the structural and biophysical analysis of selected photoreceptors and their development into "OptoGPCRs", light-controlled molecular switches with a wide range of applications in biology and medicine.

8 Nov 2020

Antiangiogenic drugs increase the aggressiveness of some kidney tumors

Angiogenesis is the process by which tumors create new blood vessels that will provide them the nutrients to continue growing.

5 Nov 2020

SARS-CoV-2 T-cell immunity is retained for at least six months

Now, a new study published on the preprint server bioRxiv shows that functional SARS-CoV-2-specific T-cell responses are retained for six months following infection. However, the strength of this response depends on the clinical features of the primary infection.

3 Nov 2020

Researchers identify a new way to prevent skin reactions in cancer patients

Using the body's immune system to fight cancer has great potential, but can also bring serious side effects, including itchy and painful skin reactions.

27 Oct 2020

Researchers develop a novel way to simplify cellular optogenetic tools

Cellular optogenetics is a technique that allows researchers to use light to precisely control cell signaling and function in space and time enabling the investigation of mechanisms involved in disease processes.

22 Oct 2020

New technique uses light to modify disease signaling

Most diseases are caused by aberrant cell signaling processes and basic research in cell signaling is needed to identify targets for future therapeutic approaches, especially in cases where no cures or effective treatments are currently available.

22 Oct 2020

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Our immune system's capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65.

20 Oct 2020

SARS-CoV-2 spike protein triggers cell signaling pathways in lung vascular cells

A new study published on the preprint server bioRxiv in October 2020 shows that vascular cells in the lung tissue begin to secrete signaling growth factors when exposed to just the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), without the rest of the viral components.

14 Oct 2020

Physically squeezing cells can trigger cells to grow and divide faster

The closer people are physically to one another, the higher the chance for exchange, of things like ideas, information, and even infection.

14 Oct 2020

Cell Signaling News and Research

Further Reading

Researchers use massive sequencing methods to identify rare genetic bone disorder

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

COVID-19 genetic risk variants impact diverse immune cell types and severe disease manifestations

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Low testosterone can increase risk of severe COVID-19 in males

Intermediate embryonic stem cell type could lead to advances in regenerative medicine

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

Early, late stages of neurodegeneration are distinct, finds study

SARS-CoV-2 causes a unique cytokine storm, study finds

Study investigates possible link between sleep apnea and autoimmune diseases

Study sheds new light on the immune system response to COVID-19

Researchers to develop new optogenetic tools for biology and medicine

Antiangiogenic drugs increase the aggressiveness of some kidney tumors

SARS-CoV-2 T-cell immunity is retained for at least six months

Researchers identify a new way to prevent skin reactions in cancer patients

Researchers develop a novel way to simplify cellular optogenetic tools

New technique uses light to modify disease signaling

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

SARS-CoV-2 spike protein triggers cell signaling pathways in lung vascular cells

Physically squeezing cells can trigger cells to grow and divide faster

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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