Fibroblast News and Research

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Fibroblasts are connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

The obstacles to developing high-throughput 3D wound healing models

In this interview, News-Medical talks to Dr. Glauco Souza and Linda Boekestijn about their work in the wound healing space and how they devised a new high throughput 3D model for would healing.

From PromoCell 22 Mar 2022

Novel device uses tiny worms to detect lung cancer cells

Dogs can use their incredible sense of smell to sniff out various forms of cancer in human breath, blood and urine samples.

20 Mar 2022

Skin cells outside of the hair follicles play large role in the development of a pimple

Acne is among the most common skin diseases in the United States, according to the American Academy of Dermatology Association, affecting up to 50 million Americans each year. It is also among the least studied.

17 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Liver hormone suppresses alcohol consumption in primates, study shows

A hormone produced by the liver called fibroblast growth factor 21 (FGF21) suppresses alcohol consumption in primates, finds a study published February 1 in the journal Cell Metabolism.

1 Feb 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

Researchers identify first known patients with BUB1 biallelic mutations

A new study published in Science Advances described the first two patients known to have mutations in both copies of BUB1, a critical gene for cell division.

20 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Study finds all three proteins required for SARS-CoV-2 infection present in human glossopharyngeal and vagal nerves

Researchers explored the presence of coronavirus receptors in the glossopharyngeal and vagal cranial nerves.

6 Jan 2022

Study confirms coronavirus RNA synthesis occurs inside membrane-bound compartments

Researchers have experimentally proved that virus-related double-stranded RNA (dsRNA) and the sites of viral RNA synthesis are associated with one another.

22 Dec 2021

Identification of a candidate effector gene at COVID-19 risk locus

A new study focuses on developing a comprehensive platform to decode the effects of sequence variation identified by GWAS.

8 Nov 2021

Study pinpoints an entirely new approach for treatment of biliary atresia

Biliary atresia is the largest cause of end-stage liver fibrosis in children and the main reason children need liver transplants. Despite many years of worldwide research, scientists have not yet found a way to prevent the condition.

7 Sep 2021

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

7 Sep 2021

Study highlights the robustness of miRNA modulation during aging process

Aging-US published "miRNAs generated from Meg3-Mirg locus are downregulated during aging" which reported that Aging determines a multilevel functional decline and increases the risk for cardiovascular pathologies.

28 Aug 2021

Research reveals clues to how a molecule improves appearance of surgery scars

Surgical scars treated with a molecule called alphaCT1 showed a long-term improvement in appearance when compared to control scars, according to multicenter, controlled Phase II clinical trials - a finding that could help surgeons improve patient outcomes.

20 Jul 2021

Fibroblast News and Research

Further Reading

The different actions of CBD in SARS-CoV-2 infection

The obstacles to developing high-throughput 3D wound healing models

Novel device uses tiny worms to detect lung cancer cells

Skin cells outside of the hair follicles play large role in the development of a pimple

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Liver hormone suppresses alcohol consumption in primates, study shows

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Researchers identify first known patients with BUB1 biallelic mutations

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Study finds all three proteins required for SARS-CoV-2 infection present in human glossopharyngeal and vagal nerves

Study confirms coronavirus RNA synthesis occurs inside membrane-bound compartments

Identification of a candidate effector gene at COVID-19 risk locus

Study pinpoints an entirely new approach for treatment of biliary atresia

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Study highlights the robustness of miRNA modulation during aging process

Research reveals clues to how a molecule improves appearance of surgery scars

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Specialized protein appears to regulate key step in cancer metastasis

Molecular imaging can improve therapeutic management of pancreatic ductal adenocarcinomas

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