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Novel method could help analyze GWAS results for sporadic diseases

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies can contribute to sporadic Parkinson's disease (PD). The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.

21 Apr 2016

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain

From Pittcon 21 Apr 2016

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Despite a shortage of corneas for transplant purposes, new research reveals that eyes are the one body part we are least likely to donate.

19 Apr 2016

Study shows how homosexuality exists among humans throughout history

Around half of all heterosexual men and women potentially carry so-called homosexuality genes that are passed on from one generation to the next. This has helped homosexuality to be present among humans throughout history and in all cultures, even though homosexual men normally do not have many descendants who can directly inherit their genes.

13 Apr 2016

Commonly used fungicides could cause gene expression changes in brain cells

Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions, including Alzheimer's disease and Huntington's disease.

31 Mar 2016

DNA changes may affect a person's lifespan

Scientists have identified DNA changes that can cut a person's lifespan by up to three years.

31 Mar 2016

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

While childhood cancer is rare (adult malignancies after 20 years are 20-30 times more common in general) it remains a major cause of death by disease in children. 15,700 children are diagnosed with cancer each year in the USA.

31 Mar 2016

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

29 Mar 2016

Research: X and Y DNA swapping may occur more often than previously thought

It turns out that the rigid "line in the sand" over which the human sex chromosomes---the Y and X--- go to avoid crossing over is a bit blurrier than previously thought. Contrary to the current scientific consensus, Arizona State University assistant professor Melissa Wilson Sayres has led a research team that has shown that X and Y DNA swapping may occur much more often.

24 Mar 2016

Diet-induced obesity, diabetes can be epigenetically inherited by offspring, say scientists

Scientists at Helmholtz Zentrum München, in collaboration with researchers from Technical University of Munich and the German Center for Diabetes Research, have shown that diet-induced obesity and diabetes can be epigenetically inherited by the offspring via both the oocytes and the sperm.

16 Mar 2016

Psychological difficulties of ovarian cancer: an interview with Katherine Taylor

Ovarian cancer affects around 7000 thousand women in the UK every year and very sadly the outcomes are not great. A women dies every 2 hours of ovarian cancer. If I am diagnosed today, I’ve only got a 40% chance of being alive in 5 years’ time.

4 Mar 2016

New MyGene2 web tool may help find genes influencing Mendelian disorders

A new web tool, MyGene2, will enable patients and their families to join clinicians and scientists in the search for genes underlying rare disorders. The sharing of health information also will improve knowledge about how gene variants influence symptoms and other clinical features of Mendelian disorders.

3 Mar 2016

New drug shows promise against Huntington's disease

A drug that would be the first to target the cause of Huntington's disease (HD) is effective and safe when tested in mice and monkeys, according to data released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

27 Feb 2016

Partner's lifestyle has greater influence on obesity risk

The lifestyle a person shares with their partner has a greater influence on their chances of becoming obese than their upbringing, research suggests.

23 Feb 2016

Research findings identify potential genetics-guided precision medicine for leukemia patients

An international research team has determined how inherited gene variations lead to severe drug toxicity that may threaten chances for a cure in children with leukemia. St. Jude Children's Research Hospital scientists led the study, results of which set the stage to expand the use of a patient's genetic make-up to tailor chemotherapy.

16 Feb 2016

Hereditary spastic paraplegia characteristics unveiled

Researchers have detailed the characteristics of a large cohort of patients with hereditary spastic paraplegias.

15 Feb 2016

Scientists pin down molecular process linked to schizophrenia origin

For the first time, researchers have managed to home in on a molecular process in the brain that contributes to the development of schizophrenia.

28 Jan 2016

Genetic code and epigenetics revealing adaption traits

A well-known songbird, the great tit, has revealed its genetic code, offering researchers new insight into how species adapt to a changing planet. Their initial findings suggest that epigenetics -- what's on rather than what's in the gene -- may play a key role in the evolution of memory and learning. And that's not just true for birds.

26 Jan 2016

PGD model could provide policy guideposts for human genome editing

Human genome editing for both research and therapy is progressing, raising ethical questions among scientists around the world.

22 Jan 2016

Study provides evidence for use of inherited genetic markers to improve melanoma prognostication

Melanoma is the most dangerous and lethal form of skin cancer. But just how long will a patient survive following the removal of a melanoma tumor? A more definitive answer to that question could come from new studies at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center. Researchers there have discovered an inherited genetic marker that might provide clinicians with a personalized tool to gauge an individual's survival and determine which patients require closer monitoring in the years following surgery.

21 Jan 2016

Inherit News and Research

Novel method could help analyze GWAS results for sporadic diseases

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Study shows how homosexuality exists among humans throughout history

Commonly used fungicides could cause gene expression changes in brain cells

DNA changes may affect a person's lifespan

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

Research: X and Y DNA swapping may occur more often than previously thought

Diet-induced obesity, diabetes can be epigenetically inherited by offspring, say scientists

Psychological difficulties of ovarian cancer: an interview with Katherine Taylor

New MyGene2 web tool may help find genes influencing Mendelian disorders

New drug shows promise against Huntington's disease

Partner's lifestyle has greater influence on obesity risk

Research findings identify potential genetics-guided precision medicine for leukemia patients

Hereditary spastic paraplegia characteristics unveiled

Scientists pin down molecular process linked to schizophrenia origin

Genetic code and epigenetics revealing adaption traits

PGD model could provide policy guideposts for human genome editing

Study provides evidence for use of inherited genetic markers to improve melanoma prognostication

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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