Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Researchers map potential toxicity of lanthanide metals used in medicine

Lanthanides are rare-earth heavy metals with useful magnetic properties and a knack for emitting light. Researchers had long assumed that lanthanides' toxicity risk was low and therefore safe to implement in a number of high-tech breakthroughs we now take for granted: from OLEDs (organic light-emitting displays)¬¬ to medical MRIs and even hybrid vehicles.

9 Jun 2021

AI-powered tool could accelerate the diagnosis of cardiovascular diseases

A team of researchers from Nanyang Technological University, Singapore, Ngee Ann Polytechnic, Singapore, and the National Heart Centre Singapore have invented a tool that could speed up the diagnosis of cardiovascular diseases.

8 Jun 2021

Treating critically ill COVID-19 patients with non-altered umbilical cord stem cells increases survival

Critically ill COVID-19 patients treated with non-altered stem cells from umbilical cord connective tissue were more than twice as likely to survive as those who did not have the treatment, according to a study published today in STEM CELLS Translational Medicine.

8 Jun 2021

Kidney experts say it’s time to remove race from medical algorithms. Doing so is complicated.

Alphonso Harried recently came across a newspaper clipping about his grandfather receiving his 1,000th dialysis treatment. His grandfather later died — at a dialysis center — as did his uncle, both from kidney disease.

8 Jun 2021

Skin disorders on the rise during COVID‐19 pandemic due to infection and PPE use

An increase in personal protective equipment (PPE) use and hygiene measures such as the use of hand sanitizers, hand washing, and mask usage during this pandemic have increased the frequency of dermatological diseases.

8 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

New study could help guide oncologists in selecting the best treatment for kidney cancers

Not all kidney cancers behave the same, with wildly different responses to immunotherapy or other treatments – and wildly different outcomes for patients as a result.

8 Jun 2021

Wearable sensor shows link between blood pressure and intracranial pressure

Brazilian researchers have simultaneously demonstrated the mechanism linking high blood pressure to elevated intracranial pressure, validated a non-invasive intracranial pressure monitoring method, and proposed a treatment for high blood pressure that does not affect intracranial hypertension.

8 Jun 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

Link between SARS-CoV-2 organotropism and kidney injury

It was clear at a relatively early stage of the pandemic that SARS-CoV-2 causes a wide range of symptoms; in addition to typical respiratory symptoms, patients also had neurological symptoms (starting with anosmia), gastrointestinal symptoms, elevated liver values, and renal, urinary or hematological changes, for example.

8 Jun 2021

Addressing climate change for better kidney health

Health has always been affected by climate and weather, but is increasingly clear that the change in climate is a significant threat to human health.

7 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a rare form of kidney inflammation (glomerulonephritis) in which the glomeruli become increasingly scarred (sclerotic), leading to progressive loss of kidney function.

7 Jun 2021

Ultrasound examinations can be deployed to detect and treat lung congestion in hemodialysis patients

Accumulation of water in the lungs (lungcongestion) is a common condition in hemodialysis patients, particularly in those at high cardiovascular risk, like those presenting coronary artery disease and/or heart failure.

7 Jun 2021

COVID-19 can cause long-term consequences for the kidneys

The kidneys are a target organ of COVID-19 and are affected very early in the course. However, this is precisely where there is strong prognostic potential: As early as last spring, COVID-19-associated nephritis was identified as an early warning signal for severe courses of the infectious disease and studies to that effect were published.

7 Jun 2021

Minimally-invasive procedure could offer hope to patients with high blood pressure

A minimally-invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicentre clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust.

7 Jun 2021

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

In a recent research paper currently available on the bioRxiv* preprint server, scientists in the US used genome-scale CRISPR knockout screens to identify factors that promote infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), revealing the potential for broad-spectrum activity across the coronavirus family.

7 Jun 2021

Analysis finds substantial disparities in COVID-19 rates among patients on hemodialysis in New York City

In an analysis of patients on hemodialysis in New York City, there were substantial racial/ethnic disparities in COVID-19 rates that were not explained by neighborhood social vulnerability.

5 Jun 2021

Study finds molecular pathway that can explain how chronic kidney disease induces heart failure

According to the Global Burden of Disease Study 2017, close to nine percent of the global population lives with some form of chronic kidney disease, or CKD. Not only does the condition affect renal function, CKD has long been associated with increased risk of cardiovascular disease.

5 Jun 2021

Weight loss drug Wegovy approved by FDA

The U.S. Food and Drug Administration (FDA) has approved Wegovy (semaglutide) injection (2.4 mg once weekly) as a chronic weight management treatment in obese or overweight adults with a weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), when used along with calorie restriction and physical activity. Wegovy, is a more potent version of Novo Nordisk's diabetes drug semaglutide.

4 Jun 2021

Nephrology News and Research

Further Reading

Researchers map potential toxicity of lanthanide metals used in medicine

AI-powered tool could accelerate the diagnosis of cardiovascular diseases

Treating critically ill COVID-19 patients with non-altered umbilical cord stem cells increases survival

Kidney experts say it’s time to remove race from medical algorithms. Doing so is complicated.

Skin disorders on the rise during COVID‐19 pandemic due to infection and PPE use

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

New study could help guide oncologists in selecting the best treatment for kidney cancers

Wearable sensor shows link between blood pressure and intracranial pressure

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

Link between SARS-CoV-2 organotropism and kidney injury

Addressing climate change for better kidney health

Study reports safety, efficacy of targeted treatment for IgA nephropathy

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Ultrasound examinations can be deployed to detect and treat lung congestion in hemodialysis patients

COVID-19 can cause long-term consequences for the kidneys

Minimally-invasive procedure could offer hope to patients with high blood pressure

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

Analysis finds substantial disparities in COVID-19 rates among patients on hemodialysis in New York City

Study finds molecular pathway that can explain how chronic kidney disease induces heart failure

Weight loss drug Wegovy approved by FDA

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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