Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

One million serious medical complications could be avoided with improvements in blood glucose levels in diabetics

Sanofi, Diabetes UK and JDRF today announce the publication of IMPACT 2 in the journal Diabetic Medicine. This new study shows that, if sustained, even modest improvement in blood glucose levels can provide significantly improved outcomes for the 3.5 million people diagnosed with diabetes in the UK.

4 Feb 2016

Researchers develop new sensor for continuous monitoring of blood flow in vascular diseases patients

Frequent measurement of blood flow changes could improve the ability of health care providers to diagnose and treat patients with vascular conditions, such as those associated with diabetes and high blood pressure.

30 Jan 2016

Mild reduction in food intake slows development of autosomal-dominant polycystic kidney disease

A small reduction in food intake—less than required to cause weight loss—dramatically slowed the development of a common genetic disorder called autosomal-dominant polycystic kidney disease (ADPKD) in mice, a new study in American Journal of Physiology—Renal Physiology reports.

30 Jan 2016

Adhering to certain diet may help postpone need for dialysis in CKD patients

Adhering to a certain diet may help postpone the need for dialysis in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

29 Jan 2016

LMU researchers reveal how crystalline deposits induce cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now elucidated how the insoluble deposits induce cell death.

29 Jan 2016

10 million of us lack sunshine vitamin

Health pioneers BetterYou have welcomed the views of Nutritionist Marilyn Glenville, that ‘oil based supplements can help you get your recommended dose of vitamin D’.

From BetterYou Ltd 27 Jan 2016

$Parathyroid hormone may mediate antihypertensive fracture risk$

Parathyroid hormone may mediate antihypertensive fracture risk

Parathyroid hormone levels may be elevated by use of some antihypertensive agents but reduced by others, analysis of the Multi-Ethnic Study of Atherosclerosis suggests.

22 Jan 2016

Levels of mitochondrial DNA in the blood may predict chronic kidney disease risk

The health of blood cells' energy-producing mitochondria may predict a person's risk of developing chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

22 Jan 2016

New study identifies DKK3 as a driver of kidney fibrosis

Chronic kidney disease can develop in response to a variety of insults and is characterized by progressive renal fibrosis and atrophy of kidney tubule. Therapeutic options are limited and the disease is often not detected until later stages.

22 Jan 2016

Fibrosis in kidney transplants driven by continuous injury

Clinically, kidney fibrosis can be used to assess stage, progression, and prognosis for both kidney transplants and kidney disease. There is debate as to whether kidney fibrosis is a maladaptive, injury-triggered process that inherently progresses to kidney failure or an adaptive wound-healing process that stabilizes the injury site.

22 Jan 2016

USRDS report shows positive and negative trends in kidney disease in the U.S.

The annual data report from the United States Renal Data System reveals both positive and negative trends in kidney disease in the U.S.

18 Jan 2016

PK molecule could be a target for vascular complications linked to type 1 diabetes

In an article published ahead of print on November 24, 2015 in the journal Diabetes (available at http://dx.doi.org/10.2337/db15-0930), researchers from the Medical University of South Carolina, the American University of Beirut, and Case Western Reserve University report that a molecule called pre-kallikrein (PK) could be a target for the vascular complications associated with type 1 diabetes.

18 Jan 2016

JINARC (tolvaptan) accepted for use in Scotland for ADPKD treatment

From today, people in Scotland with the genetic kidney disease ADPKD could benefit from JINARC® (tolvaptan) following advice issued by the Scottish Medicines Consortium (SMC) for its use in adults with chronic kidney disease (CKD) stages 1-3 at the start of treatment with evidence of rapidly progressing disease.

12 Jan 2016

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on gastrointestinal and cardio-renal diseases, today announced positive results of an open label clinical study evaluating the pharmacodynamic (PD) activity of RDX022 in healthy adult volunteers.

5 Jan 2016

Araim Pharmaceuticals forms new strategic collaboration with Vault Bioventures to market novel peptides

Araim Pharmaceuticals has formed a long-term strategic partnership with Vault Bioventures to facilitate the advancement to market of its novel peptide library which targets devastating injuries and chronic diseases underserved by current therapies.

4 Jan 2016

Infusing small dose of cytokine can prevent or reverse diabetes-related kidney failure

Diabetes is the leading cause of kidney failure, and scientists have found that infusing just a small dose of a cytokine, thought to help cause that failure, can instead prevent or reverse it.

29 Dec 2015

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

As we age, proteins in the lenses of our eyes start misbehaving: They unfold and congregate in clusters that block, scatter and distort light as it passes through the lens. A cloudy area, or cataract, forms. In a new study, scientists found that throughout our lifetime, levels of a key protein decline, and may be an early warning sign of a developing cataract.

23 Dec 2015

Prevalence of chronic kidney disease considerably varies across Europe

The first study to carefully characterize the prevalence of chronic kidney disease (CKD) across Europe found considerable variation. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology.

22 Dec 2015

Variant signs worldwide exclusive license and development agreement with L&F Research

Variant Pharmaceuticals, Inc., an emerging pharmaceutical company focusing on rare diseases and other specialty conditions with limited or sub-optimal therapeutic options, announced today a worldwide exclusive license and development agreement with L&F Research LLC to advance development of Variant's lead product, VAR 200.

20 Dec 2015

Basaglar (insulin glargine injection) approved to improve glycemic control in diabetes patients

The U.S. Food and Drug Administration today approved Basaglar (insulin glargine injection), a long-acting human insulin analog to improve glycemic control in adult and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.

17 Dec 2015

Nephropathy News and Research

Further Reading

One million serious medical complications could be avoided with improvements in blood glucose levels in diabetics

Researchers develop new sensor for continuous monitoring of blood flow in vascular diseases patients

Mild reduction in food intake slows development of autosomal-dominant polycystic kidney disease

Adhering to certain diet may help postpone need for dialysis in CKD patients

LMU researchers reveal how crystalline deposits induce cell death

10 million of us lack sunshine vitamin

Parathyroid hormone may mediate antihypertensive fracture risk

Levels of mitochondrial DNA in the blood may predict chronic kidney disease risk

New study identifies DKK3 as a driver of kidney fibrosis

Fibrosis in kidney transplants driven by continuous injury

USRDS report shows positive and negative trends in kidney disease in the U.S.

PK molecule could be a target for vascular complications linked to type 1 diabetes

JINARC (tolvaptan) accepted for use in Scotland for ADPKD treatment

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Araim Pharmaceuticals forms new strategic collaboration with Vault Bioventures to market novel peptides

Infusing small dose of cytokine can prevent or reverse diabetes-related kidney failure

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

Prevalence of chronic kidney disease considerably varies across Europe

Variant signs worldwide exclusive license and development agreement with L&F Research

Basaglar (insulin glargine injection) approved to improve glycemic control in diabetes patients

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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