Nucleic Acid News and Research

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A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

Researchers described the development and applications of a 3D-printed lab-on-a-chip device that quickly detected the presence of SARS-CoV-2 in patient's saliva.

10 Aug 2022

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Researchers assess the sensitivity of the SARS-CoV-2 Omicron BA.2.75 sublineage to neutralization.

9 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

New dual-plasmid editing system for DNA-based information rewriting in vivo

DNA-based information is a new interdisciplinary field linking information technology and biotechnology.

5 Aug 2022

Saliva-based self-testing platform detects SARS-CoV-2 with the same level of sensitivity as PCR tests

PCR tests, also called molecular tests or nucleic acid tests, are considered the gold standard in detecting the presence of SARS-CoV-2, the virus that gives rise to COVID-19.

5 Aug 2022

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

University of California, Irvine researchers have developed a COVID-19 test that detects and identifies specific SARS-CoV-2 variants with 100% accuracy.

3 Aug 2022

Inexpensive, self-driven microfluidic chip rapidly detects Hepatitis C virus in about 45 minutes

Hepatitis C affects more than 354 million people worldwide. About 75 to 85 percent of people who have it get a long-term infection referred to as chronic Hepatitis C. Left untreated, it could lead to cirrhosis, liver cancer or liver failure.

3 Aug 2022

New and efficient method Monkeypox virus sequencing

In a recent study posted to the medRxiv* preprint server, Spanish researchers described a new enrichment method for metagenomic sequencing of the monkeypox virus (MPXV).

2 Aug 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

The role of cellular or cytokine response and vaginal microbiome dysbiosis in the clearance, persistence, and recurrence of HPV infection

Researchers have reviewed the role of cytokine or cellular response and vaginal microbiome dysbiosis in the persistence, clearance, and recurrence of HPV infection

28 Jul 2022

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

In a new study, investigators studied a linear deoxyribonucleic acid (linDNA) SARS-CoV-2 vaccine option in felines.

27 Jul 2022

Innovative technology reveals new insights into cellular reservoirs of HIV

In a presentation today at AIDS 2022, the 24th International AIDS Conference in Montreal, scientists with the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC) and their collaborators described how their use of cutting-edge technology revealed new insights into cellular reservoirs of HIV and what those observations could mean for the next steps in HIV cure research. NIAID is part of the National Institutes of Health.

27 Jul 2022

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Researchers assessed the biodistribution and safety of SBCoV202, a novel antiviral agent based on antisense technology that can specifically and effectively bind to the SARS-CoV-2 genome target to inhibit SARS-CoV-2 replication.

27 Jul 2022

Scientists explore post-COVID-19 conditions among children

Scientists evaluated post coronavirus disease 2019 conditions across children 90 days following COVID-19.

27 Jul 2022

MolGen showcases its lab automation solutions at AACC in Chicago

MolGen B.V. of Veenendaal (NL), a global solutions provider of hardware, reagents, consumables, software and service for human and animal diagnostics, the agriculture and biotech industries, participates in the American Association for Clinical Chemistry Fair (AACC) in Chicago on July 24th - 28th, 2022.

From AgriGenX 25 Jul 2022

Nucleic Acid News and Research

A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

New dual-plasmid editing system for DNA-based information rewriting in vivo

Saliva-based self-testing platform detects SARS-CoV-2 with the same level of sensitivity as PCR tests

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

Inexpensive, self-driven microfluidic chip rapidly detects Hepatitis C virus in about 45 minutes

New and efficient method Monkeypox virus sequencing

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

The role of cellular or cytokine response and vaginal microbiome dysbiosis in the clearance, persistence, and recurrence of HPV infection

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

Innovative technology reveals new insights into cellular reservoirs of HIV

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Scientists explore post-COVID-19 conditions among children

MolGen showcases its lab automation solutions at AACC in Chicago

Microplate optimised for magnetic bead separations

New anticoagulant platform holds promise as a revolutionary advancement over the current blood thinners

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

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