Omicron News and Research

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Antibody combination strongly protects high-risk people with early COVID-19 symptoms, trial shows

A treatment combining two antibodies against the coronavirus SARS-CoV-2 strongly protected high-risk people with early COVID-19 symptoms from hospitalization and death in an international Phase 2/3 clinical trial conducted in the first half of 2021 and co-led by researchers at Weill Cornell Medicine and NewYork-Presbyterian.

20 Apr 2023

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Researchers explored the impact of a loss-of-function mutation in the SARS-CoV-2 Omicron variants on the expression of the spike protein.

20 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Omicron News and Research

Antibody combination strongly protects high-risk people with early COVID-19 symptoms, trial shows

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Study highlights the importance of bivalent mRNA booster vaccination in populations at high risk of severe COVID-19

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Antibody response to SARS-CoV-2 is stronger and more durable in infants and young children

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Bivalent COVID-19 boosters provide durable, effective protection against omicron subvariants

The virological characteristics of XBB.1.16

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

SARS-CoV-2 infection among infants born to maternal COVID-19 cases during Omicron variant predominance

New insights into how Omicron variants avoid destruction by "killer" T cells

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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