Peptides News and Research

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Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product.

19 Jul 2024

Llama-derived molecules target hidden strains of HIV

A research team at Georgia State University has developed tiny, potent molecules that are capable of targeting hidden strains of HIV. The source? Antibody genes from llama DNA.

17 Jul 2024

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Tirzepatide, a novel twincretin drug, significantly improves weight loss and glycemic control in obese and type 2 diabetes patients, outperforming traditional treatments in clinical trials.

15 Jul 2024

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

DNA aptamers of melanopsin that regulate the clock hands of biological rhythms were developed by the Toyohashi University of Technology and the National Institute of Advanced Industrial Science and Technology (AIST) group.

12 Jul 2024

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

A study led by the Hospital del Mar Research Institute, with Cima University of Navarra and Pompeu Fabra University, has identified a group of small molecules exclusive to liver tumors that could be key to developing cancer vaccines.

11 Jul 2024

Enzyme breakthrough could revolutionize the production of greener cancer treatments

Scientists from The University of Manchester have uncovered a more efficient and sustainable way to make peptide-based medicines, showing promising effectiveness in combating cancers.

10 Jul 2024

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Antibiotics are a cornerstone of modern medicine. They are regularly used to treat bacterial infections or as a prophylactic measure during surgery to prevent infection.

3 Jul 2024

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for developing new antibiotic treatments.

2 Jul 2024

Nanorobots with hidden weapons for precision cancer therapy

Researchers at Karolinska Institutet in Sweden have developed nanorobots that kill cancer cells in mice.

1 Jul 2024

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

27 Jun 2024

Study finds women lost more of their body weight on average with semaglutide than men

Researchers performed a secondary analysis of the semaglutide treatment effect in people with obesity and heart failure with a preserved left ventricular ejection fraction program that included individuals with diabetes mellitus, stratified by biological sex.

26 Jun 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Semaglutide provides double benefit for women with heart failure

Semaglutide, a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options.

24 Jun 2024

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

A new paper from an interdisciplinary team at MUSC Hollings Cancer Center describes how the bacteria Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy, allowing oral cancer tumors to become resistant to the drug's effects.

18 Jun 2024

Deep learning revives ancient peptides to battle antibiotic resistance

Researchers used deep learning to resurrect antibiotic peptides from extinct organisms, offering new solutions for combating antibiotic resistance.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Peptides News and Research

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

Llama-derived molecules target hidden strains of HIV

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

Enzyme breakthrough could revolutionize the production of greener cancer treatments

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

Nanorobots with hidden weapons for precision cancer therapy

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Study finds women lost more of their body weight on average with semaglutide than men

New enzyme targets hold promise for cancer therapies

Semaglutide provides double benefit for women with heart failure

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

Deep learning revives ancient peptides to battle antibiotic resistance

UD researchers pioneer universal, economical method for proteomics sample preparation

Discovery could accelerate efforts to produce new antibiotics in the fight against antimicrobial resistance

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Simple peptide modification could unlock a whole class of targets for drug discovery

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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