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Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

In this interview conducted at Pittcon 2024, we spoke to Professor John Yates about capturing cardiomyocyte cell-to-cell heterogeneity via shotgun top-down proteomics.

From Pittcon 6 Aug 2024

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

In an effort to combat one of the most lethal forms of pediatric brain cancer, researchers at the UCLA Health Jonsson Comprehensive Cancer Center are launching a first-of-its-kind clinical trial to evaluate the safety and effectiveness of a cancer vaccine targeting H3 G34-mutant diffuse hemispheric glioma, a highly aggressive brain tumor that is typically found in adolescents and young adults.

5 Aug 2024

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.

5 Aug 2024

Groundbreaking method dmSLAY improves antimicrobial peptide effectiveness and safety

Researchers developed a high-throughput method, dmSLAY, to assess thousands of AMP variants, combining it with machine learning to enhance membrane selectivity and reduce toxicity.

1 Aug 2024

AI unlocks potential of antimicrobial peptides for new antibiotics

In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers at The University of Texas at Austin have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials.

1 Aug 2024

Machine learning-based taste predictor developed for identifying bitter, sweet, and umami from other taste sensations

Researchers developed VirtuousMultiTaste, a machine-learning tool to distinguish between sweet, umami, and bitter tastes based on a compound's molecular structures and underlying physicochemical characteristics.

31 Jul 2024

GLP-1-based polyagonists: A promising weight loss alternative to bariatric surgery

Researchers highlight the unprecedented success of GLP-1-based multi-receptor drugs in achieving substantial weight loss and improved health outcomes, potentially replacing bariatric surgery for obesity treatment.

28 Jul 2024

Study reveals enhanced electron transport in folded peptides

What puts the electronic pep in peptides? A folded structure, according to a new study in the Proceedings of the National Academy of Sciences.

26 Jul 2024

New review highlights advances in diabetes research and treatment

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

25 Jul 2024

Oligodendrocytes identified as key source of amyloid beta in Alzheimer's disease

Oligodendrocytes are an important source of amyloid beta (Aβ) and play a key role in promoting neuronal dysfunction in Alzheimer's disease (AD), according to a study published July 23, 2024 in the open-access journal PLOS Biology by Rikesh Rajani and Marc Aurel Busche from the UK Dementia Research Institute at University College London, and colleagues.

23 Jul 2024

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control.

23 Jul 2024

New microscopy technique unveils dynamic structure of amyloid-beta

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's.

19 Jul 2024

Tiny animals steal antibiotic secrets from bacteria to fight disease

A group of small, freshwater animals protect themselves from infections using antibiotic recipes "stolen" from bacteria, according to new research by a team from the University of Oxford, the University of Stirling and the Marine Biological Laboratory (MBL), Woods Hole.

19 Jul 2024

Peptides News and Research

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Groundbreaking method dmSLAY improves antimicrobial peptide effectiveness and safety

AI unlocks potential of antimicrobial peptides for new antibiotics

Machine learning-based taste predictor developed for identifying bitter, sweet, and umami from other taste sensations

GLP-1-based polyagonists: A promising weight loss alternative to bariatric surgery

Study reveals enhanced electron transport in folded peptides

New review highlights advances in diabetes research and treatment

Oligodendrocytes identified as key source of amyloid beta in Alzheimer's disease

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

New microscopy technique unveils dynamic structure of amyloid-beta

Tiny animals steal antibiotic secrets from bacteria to fight disease

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

Llama-derived molecules target hidden strains of HIV

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

Enzyme breakthrough could revolutionize the production of greener cancer treatments

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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