Periodontitis News and Research

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Gene causing periodontitis, rheumatoid arthritis and osteoporosis identified

Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development of diseases such as periodontitis (gum disease), rheumatoid arthritis and osteoporosis. The study, which will be published online August 30, ahead of print, in the journal Nature Medicine, could lead to new treatments in the future.

2 Sep 2009

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

31 Aug 2009

Prominent cardiologist to present keynote at American Academy of Periodontology 95th Annual Meeting

Nearly 75 percent of Americans suffer from some form of periodontal disease, the major cause of adult tooth loss. In addition, cardiovascular disease, the leading killer of men and women in the United States, is a major public health issue contributing to 2,400 deaths each day. And while these two conditions are seemingly unrelated, research suggests that managing one disease may reduce the risk for the other.

4 Aug 2009

Periodontitis and atherosclerotic cardiovascular disease

Additional research is called for and patients with moderate to severe periodontitis should receive evaluation and possible treatment to reduce their risk of atherosclerotic cardiovascular disease (CVD), according to a special consensus paper by editors of The American Journal of Cardiology and Journal of Peridontology in the July 1, 2009 issue of The American Journal of Cardiology, published by Elsevier.

30 Jun 2009

Discovery of genetic link between periodontitis and heart attack

The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. Although a genetic link seemed likely, until now its existence was uncertain. Now, for the first time, scientists have discovered a genetic relationship between the two conditions, a researcher told the annual conference of the European Society of Human Genetics today (Monday 25 May).

25 May 2009

Discovery of new target in fight against osteoporosis, periodontitis

Osteoporosis and periodontitis are common diseases whose sufferers must cope with weakness, injury and reduced function as they lose bone more quickly than it is formed. While the mechanism of bone destruction in these diseases is understood, scientists have had less information about how bone formation is impaired.

19 May 2009

Closer to an effective treatment for gum disease in smokers

Scientists in the USA have discovered why smokers may be more prone to chronic gum disease (periodontitis). One of the bacteria responsible for this infection responds to cigarette smoke - changing its properties and the way it infects a smokers mouth.

11 May 2009

Study on Haitian children shows poor diet contribute to gum disease

Haiti's children, already burdened with poverty and malnutrition, may have a health problem related to these chronic conditions -- gum disease.

1 Apr 2009

Blocking one protein RANK function inhibits bone loss

Soo Young Lee and colleagues, at Ewha Womans University, Republic of Korea, have developed a cell-permeable inhibitor of the mouse protein RANK (which they termed RRI) that is likely to aid in the development of selective drugs to treat diseases that involve substantial bone loss, for example, osteoporosis, periodontitis, and arthritis.

2 Mar 2009

Quit smoking one week at a time

Even though millions of smokers will resolve to 'butt out' on January 1st, experts say many will be still be smoking on Valentine's Day. They have some tips to help quitters retain their resolve and strengthen their commitment to quitting which apply even to the likes of President-elect Barack Obama.

29 Dec 2008

Dieting may help reduce the risk of gum disease, mostly in men

For men, especially older men, dieting may help reduce the risk of gum disease more than for women, according to a new study by researchers at the University of Maryland, Baltimore and other institutions.

17 Dec 2008

Gene therapy used to treat periodontal disease

Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults.

12 Dec 2008

Epstein-Barr virus linked to inflammatory diseases of the mouth

Researchers at Oregon Health & Science University's School of Dentistry have found that a significant percentage of dental patients with the inflammatory diseases irreversible pulpitis and apical periodontitis also have the Epstein-Barr virus.

11 Nov 2008

Study shows high gum disease rates in rural Appalachia

Research on 445 families centered in two Pennsylvania towns and two West Virginia counties shows that 80 percent of adults suffer from more severe forms of periodontal disease, according to Richard Crout, D.M.D., Ph.D., an expert on gum disease and associate dean for research in the West Virginia University School of Dentistry.

14 Sep 2008

Scaling and root planing dental treatment safe for pregnant women

Pregnant women can safely undergo essential dental treatment and receive topical and local anesthetics at 13 to 21 weeks gestation, says a study published in the June issue of The Journal of the American Dental Association.

11 Jun 2008

Periodontitis and human papillomavirus combined increase risk for tongue cancer

Persons with periodontitis who also are infected with human papillomavirus (HPV) are at increased risk of developing tongue cancer, new research conducted at the University at Buffalo School of Dental Medicine has shown.

7 Apr 2008

Gene expression differences between Europeans and Africans affect response to drugs, infections

Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.

28 Feb 2008

Regular use of marijuana increases risk for gum disease

Regular use of marijuana (cannabis) in young adulthood is associated with periodontal (gum) disease, according to a study in the February 6 issue of JAMA.

7 Feb 2008

Take care of your teeth and gums for a healthy heart

Each year, cardiovascular disease kills more Americans than cancer. And while most people are aware that lifestyle choices such as eating right, getting enough exercise and quitting smoking can help prevent cardiovascular disease, they may not know that by just brushing and flossing their teeth each day, they might also be avoiding this potentially lethal condition.

9 Jan 2008

Effect of periodontal diseases on medical and dental costs

A new study in the November issue of the Journal of Periodontology (JOP) found that prevention of periodontal diseases may lead to savings on not only dental costs, but also medical care costs.

27 Nov 2007