Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 8, one copy inherited from each parent, form one of the pairs. Chromosome 8 spans about 146 million DNA building blocks (base pairs) and represents between 4.5 percent and 5 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 8 likely contains between 700 and 1,100 genes.
Genes on chromosome 8 are among the estimated 20,000 to 25,000 total genes in the human genome.
The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes. This achievement is described in the April 1, 2004 edition of the journal Nature.
The Oxford Genetics Knowledge Park is a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, and is one of six such Parks nationally, funded by the Departments of Health and Trade and Industry. The aim of the Genetics Knowledge Parks (GKPs) is to translate advances in genetics research into clinical practice.
An international research team, supported by the National Institutes of Health (NIH), today announced it has completed a high-quality, draft sequence of the genome of the laboratory rat, and has used that data to explore how the rat's genetic blueprint stacks up against those of mice and humans.
The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes.
With the identification of the gene responsible for a newly recognized type of mental retardation, researchers at Beth Israel Deaconess Medical Center (BIDMC) have also discovered what appears to be the key target in the evolution of the frontal lobes of the brain's cerebral cortex. The findings offer a key insight into the complex puzzle of human brain development - and the evolution of human behavior.
Researchers at Harvard-affiliated Dana-Farber Cancer Institute have pinpointed a crucial gene on which the normal development of the body's entire blood system depends. If the gene is absent, even the most basic blood stem cells cannot be generated. In a mutated form, this gene can cause a rare and devastating form of leukemia.
International research teams studying two distinct populations have found variants in a gene that may predispose people to type 2 diabetes, the most common form of the disease. The researchers, who collaborated extensively in their work, report their findings in companion articles in the April issue of Diabetes.
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