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Research reveals how disordered protein interaction orchestrates gene expression

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated.

25 Nov 2021

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field.

25 Nov 2021

International collaboration secures €1M grant to investigate new treatment target for lymphoma

An international collaboration involving researchers from Queen Mary University of London, Memorial Sloan Kettering Cancer Center, New York and Dana-Farber Cancer Institute, Boston has secured a €1M research grant from Dutch blood cancer charity, Lymph&Co, to investigate a new treatment target for lymphoma.

25 Nov 2021

New, improved organoids shed light on untreatable form of prostate cancer

A multi-institutional team of investigators led by bioengineer Ankur Singh has developed research tools that shed new light on a virtually untreatable form of prostate cancer, opening a pathway that may lead to novel therapeutics and a glimmer of hope for patients.

24 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Decline in CT imaging during the pandemic may raise the possibility of poorer cancer outcomes

Significant decreases in CT imaging for cancer persisted even after the peak of the COVID-19 pandemic in 2020, delaying diagnosis and treatment and raising the possibility of more advanced cancers and poorer outcomes for patients in the future, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

24 Nov 2021

Study offers insights into how Shigella delivers bacterial proteins into our cells

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

New model describes how cultural traumas may drive health disparities

A pair of researchers at the University of California, Riverside, has proposed a new model of "cultural trauma" that describes how traumas such as colonization, hate crimes, and recent anti-immigrant media and policies may drive health disparities in many U.S. cultural groups.

23 Nov 2021

Study shows how inadequate sleep can jeopardize brain organization in early adolescence

We all know that if we don't get enough sleep or don't sleep well, we won't be on top of our game the next day.

22 Nov 2021

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists from Nagoya University, Japan, led by Associate Professor Akio Masuda, have recently identified the mechanism behind regulated splicing of large constitutive exons which are rich in disordered regions, and their potential involvement in the assembly of transcription factors.

21 Nov 2021

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices.

21 Nov 2021

Harvard Chan School and SAHZU announce the launch of bilateral exchange program in clinical research

The Harvard T.H. Chan School of Public Health and Zhejiang University School of Medicine in Hangzhou, China, today announced the launch of a bilateral exchange program in clinical research to enhance the research capabilities of both institutions and to develop a multi-year program of clinical research education.

20 Nov 2021

The Power of Digitalization in the Life Sciences and Diagnostics Sectors

In this interview, News-Medical talks to Frank Buescher and Wael Yared about the increasing digitalization of the life sciences and diagnostics sectors and the possibilities this entails.

From Tecan 19 Nov 2021

Study involving a rat model offers potential treatment for Alexander disease

Alexander disease is a progressive and rare neurological disorder with no cure or standard course of treatment. But a new study led by researchers at the University of Wisconsin–Madison involving a rat model of the disease offers a potential treatment for the typically fatal condition.

18 Nov 2021

New study highlights the important role of rare genomic differences in OCD risk

Both rare and commonly observed differences in the DNA letters strung along a person's chromosomes can explain about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD), according to a new study led by scientists at the Icahn School of Medicine at Mount Sinai.

18 Nov 2021

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

A novel gene therapy for hemophilia A led to sustained expression of the clotting factor those patients lack, resulting in a reduction – or in some cases complete elimination – of painful and potentially life-threatening bleeding events, according to a new study led by researchers at Children's Hospital of Philadelphia.

18 Nov 2021

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.

18 Nov 2021

$10 million gift helps launch the Colton Center for Autoimmunity at Penn

Thanks to a generous $10 million gift from Stewart and Judy Colton, the Perelman School of Medicine at the University of Pennsylvania will continue to be on the leading edge of autoimmune research and care with the launch of the Colton Center for Autoimmunity at Penn.

18 Nov 2021

Public opinion is unified on lowering prescription drug prices. Why are leaders settling for less?

Democrats and Republicans are crystal clear in polls that they want government to be allowed to negotiate down high drug prices. Americans pay nearly three times as much for drugs as patients in dozens of other countries.

18 Nov 2021

Boston Children's receives NIH grant to co-lead HEALthy Brain and Child Development study

Boston Children's Hospital has been awarded two five-year grants by the National Institutes of Health to co-lead the HEALthy Brain and Child Development (HBCD) study, an ambitious, comprehensive national study of brain development from birth through early childhood.

17 Nov 2021

Medical School News and Research

Research reveals how disordered protein interaction orchestrates gene expression

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

International collaboration secures €1M grant to investigate new treatment target for lymphoma

New, improved organoids shed light on untreatable form of prostate cancer

New technique may be a significant leap forward in the understanding of human cells

Decline in CT imaging during the pandemic may raise the possibility of poorer cancer outcomes

Study offers insights into how Shigella delivers bacterial proteins into our cells

New model describes how cultural traumas may drive health disparities

Study shows how inadequate sleep can jeopardize brain organization in early adolescence

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

Harvard Chan School and SAHZU announce the launch of bilateral exchange program in clinical research

The Power of Digitalization in the Life Sciences and Diagnostics Sectors

Study involving a rat model offers potential treatment for Alexander disease

New study highlights the important role of rare genomic differences in OCD risk

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

$10 million gift helps launch the Colton Center for Autoimmunity at Penn

Public opinion is unified on lowering prescription drug prices. Why are leaders settling for less?

Boston Children's receives NIH grant to co-lead HEALthy Brain and Child Development study

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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