Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

New method for identifying patients with newly diagnosed HIV using electronic medical records

A new, validated software-based method for identifying patients with newly diagnosed HIV using electronic medical records (EMRs) is described in AIDS Research and Human Retroviruses, a peer-reviewed journal published by Mary Ann Liebert, Inc., publishers.

15 Jul 2014

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Advanced Cell Diagnostics Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced that its RNAscope® RNA in situ hybridization technology has reached two major milestones. In just three years, over 100 peer-reviewed papers featuring the technology have been published, and with the significant increase in use of RNAscope, ACD has now built a library of over 4000 target probes for numerous species. Probes are designed to order in under two weeks, and in just six months the library has grown by over 1500, reflecting the wide interest in ACD’s breakthrough technology.

From Advanced Cell Diagnostics 15 Jul 2014

DARPins could revolutionize protein therapeutics

Integrating an INTEGRA VIAFLO 96 multichannel pipette into their high throughput expression facility has enabled Molecular Partners (Zurich, Switzerland) to streamline the discovery and development of a novel class of targeted protein therapeutics termed DARPins.

From INTEGRA Biosciences 15 Jul 2014

Researchers develop new software to identify severity of cancer

Together with the company Tissuegnostics, the pathologist Lukas Kenner and his colleagues have developed a software that is able to identify cancer cells in tissue sections and demonstrate the presence of specific biomarkers on cells. The overall information provides a precise picture of the disease and leads to the most suitable treatment.

15 Jul 2014

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich (LMU) and the Technische Universität München (TUM) have moved an important step closer to understanding molecular mechanisms of autoimmune diseases.

14 Jul 2014

Researchers examine why antioxidant actually do more harm than good

For decades, health-conscious people around the globe have taken antioxidant supplements and eaten foods rich in antioxidants, figuring this was one of the paths to good health and a long life.

11 Jul 2014

High-resolution, high-throughput pre-implantation genetic screening microarray launched by OGT

Oxford Gene Technology (OGT), The Molecular Genetics Company, has announced the launch of a new high-resolution, high-throughput pre-implantation genetic screening (PGS) microarray aimed at improving embryo screening for in vitro fertilisation (IVF). The CytoSure™ Embryo Screen Array offers eight arrays of 60,000 spots for high-resolution genome-wide aneuploidy and copy number detection in pre-implantation embryos.

From Oxford Gene Technology 8 Jul 2014

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

Researchers at Karolinska Institutet in Sweden have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself - but just as important is how this study, which is published in the highly respected journal Nature Methods, was conducted.

8 Jul 2014

Scientists develop chip for detection of RNA strand of dengue fever virus

Scientists at the Center for Research and Advanced Studies (Cinvestav) in Mexico developed a chip (also known as cDNA microarray) that allows detection of the RNA strand of the dengue fever virus.

7 Jul 2014

Scientists find unexpected degree of complexity in transcriptional enhancers’ interactions

Contrary to what was thought, sequences of DNA called enhancers - which control a gene's output - find their targets long before they are activated during embryonic development, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

4 Jul 2014

Webinar outlines novel findings from RNA-Seq project performed by OGT

Oxford Gene Technology (OGT), The Molecular Genetics Company, has made the latest in its series of educational webinars available to watch online at www.ogt.com/webinars. In the webinar entitled “Developing new insights into gene expression using RNA-Seq”, Dr Christopher Jones, Research Fellow at the Brighton and Sussex Medical School (BSMS), UK, presents novel findings from a recent RNA-Seq project performed by OGT.

From Oxford Gene Technology 2 Jul 2014

A*STAR scientists pioneered a molecular connection between obesity and diabetes

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, have discovered that obese individuals lack a protein that is essential for regulating blood glucose levels, causing them to face higher risks of developing diabetes.

1 Jul 2014

New Tel Aviv University study finds link between Alzheimer's and brain hyperactivity

Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and why this elevated activity takes place hasn't yet been explained - until now.

1 Jul 2014

Video interview highlights latest research developments in women’s reproductive health using Chromatrap solid state ChIP assay

An informative video interview with Professor Steve Conlan of the College of Medicine at Swansea University (UK) highlights the latest research developments in women’s reproductive health using unique molecular biology tools.

From Chromatrap® - Porvair Sciences Ltd 30 Jun 2014

Members of JUGGLE network collaborate to improve project coordination

The field of life sciences is at the crossroads of biology and medicine and is a key component of the research portfolio of Johannes Gutenberg University Mainz (JGU).

28 Jun 2014

New data analysis technique improves monitoring of kidney patients

A new data analysis technique radically improves monitoring of kidney patients, according to a University of Leeds-led study, and could lead to profound changes in the way we understand our health.

28 Jun 2014

University of Utah researcher to receive Nelson Trust Award for Retinitis Pigmentosa

Research to Prevent Blindness, a New York-based foundation, has announced that University of Utah researcher Wolfgang Baehr, Ph.D., will receive the Nelson Trust Award for Retinitis Pigmentosa-and an accompanying $100,000 to pursue new scientific leads to understand contributors to blindness.

27 Jun 2014

Molecule that blocks bone destruction could provide potential therapeutic target for osteoporosis

UT-Southwestern cancer researchers have identified a promising molecule that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone metastases of cancer.

26 Jun 2014

Discovery provides scientists with better understanding of limiting uncontrolled cell growth

Biologists at UC San Diego have found the "missing link" in the chemical system that enables animal cells to produce ribosomes-the thousands of protein "factories" contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.

24 Jun 2014

Study paves way to develop novel therapies for nasopharyngeal cancer

A team of scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, National University Cancer Institute Singapore (NCIS) and National University Hospital Singapore (NUH), discovered a distinct mutational signature and nine significantly mutated genes associated with nasopharyngeal cancer, paving the way to developing novel therapies for this deadly disease.

23 Jun 2014

Molecular Biology News and Research

Further Reading

New method for identifying patients with newly diagnosed HIV using electronic medical records

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

DARPins could revolutionize protein therapeutics

Researchers develop new software to identify severity of cancer

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Researchers examine why antioxidant actually do more harm than good

High-resolution, high-throughput pre-implantation genetic screening microarray launched by OGT

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

Scientists develop chip for detection of RNA strand of dengue fever virus

Scientists find unexpected degree of complexity in transcriptional enhancers’ interactions

Webinar outlines novel findings from RNA-Seq project performed by OGT

A*STAR scientists pioneered a molecular connection between obesity and diabetes

New Tel Aviv University study finds link between Alzheimer's and brain hyperactivity

Video interview highlights latest research developments in women’s reproductive health using Chromatrap solid state ChIP assay

Members of JUGGLE network collaborate to improve project coordination

New data analysis technique improves monitoring of kidney patients

University of Utah researcher to receive Nelson Trust Award for Retinitis Pigmentosa

Molecule that blocks bone destruction could provide potential therapeutic target for osteoporosis

Discovery provides scientists with better understanding of limiting uncontrolled cell growth

Study paves way to develop novel therapies for nasopharyngeal cancer

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