Receptor News and Research

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Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Spike protein could be responsible for memory loss in post-COVID-19 syndrome

Patients diagnosed with post-COVID-19 syndrome often experience cognitive and memory impairments. A new study by researchers from the Federal University of Rio de Janeiro (UFRJ) and UniRio provides insight into the mechanism behind this phenomenon.

3 Apr 2023

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Researchers screened the circulating B lymphocyte repertoires of coronavirus disease 2019 convalescents and vaccines using multiplexed antigen panels.

3 Apr 2023

Study indicates interspecies transmission of SARS-CoV-2 between humans and their pets occurs regularly

Researchers assessed severe acute respiratory syndrome coronavirus 2 seroprevalence among domestic pets.

3 Apr 2023

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Researchers explored the correlation between autoimmunity and obesity.

3 Apr 2023

Tighter core of SARS-CoV-2 spike protein in new variants may have increased the virus's fitness

Just as a tight core is a component of good physical fitness for humans, helping to stabilize our bodies, mutations that tightened the core of the SARS-CoV-2 spike protein in new variants may have increased the virus's fitness.

31 Mar 2023

Study focuses on a novel mechanism of the body's regulation of salt balance

A new study led by Marshall University researchers focuses on a novel mechanism of the body's regulation of salt balance.

31 Mar 2023

Researchers develop a biosensor for real time detection of the G-protein molecular switch

DGIST (President: Kook Yang) announced on March 16th that the research team led by Professor Byung-Chang Suh has investigated for the first time the real-time effect of the G-protein cycle, which acts as a switch in our body, on the structural changes in G protein-coupled receptors (GPCRs).

31 Mar 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Researchers investigated the feasibility of utilizing a bacterial contractile injection system for programmable protein delivery.

31 Mar 2023

Common amino acid discovery improves understanding of the biological causes of depression

A common amino acid, glycine, can deliver a "slow-down" signal to the brain, likely contributing to major depression, anxiety and other mood disorders in some people, scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have found.

30 Mar 2023

CAR T-cell therapy improves quality of life for patients with blood cancers

Chimeric antigen receptor T-cell (CAR-T) therapy has transformed cancer treatment, yet relatively few studies have investigated the impact of the therapy on longitudinal patient quality of life – an aspect of care that often suffers from receiving traditional intensive cancer medications, such as chemotherapy.

30 Mar 2023

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

A study published in Cell Reports Medicine describes that COVID-19 vaccines induce strong T cell response in blood cancer patients, irrespective of antibody response and B cell numbers.

30 Mar 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Receptor News and Research

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Spike protein could be responsible for memory loss in post-COVID-19 syndrome

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Study indicates interspecies transmission of SARS-CoV-2 between humans and their pets occurs regularly

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Tighter core of SARS-CoV-2 spike protein in new variants may have increased the virus's fitness

Study focuses on a novel mechanism of the body's regulation of salt balance

Researchers develop a biosensor for real time detection of the G-protein molecular switch

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Common amino acid discovery improves understanding of the biological causes of depression

CAR T-cell therapy improves quality of life for patients with blood cancers

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

New review examines link between HDLC and different types of cancer

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Experimental anti-obesity drug may control appetite without surgery or nausea

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

COVID-19 activates endogenous retroviruses within our genome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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