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Adult stem cell therapy may benefit COPD patients

New developments in regenerative medicine are bringing about exciting, novel approaches to create therapies for hard to treat diseases. Chronic obstructive pulmonary disease (COPD) is a hard to treat disorder that progressively blocks airflow in the lungs making it increasingly difficult for an individual to breathe, and is one of the leading illnesses in the US. Yet, current treatments for COPD can only try to limit the extent of damage to the lungs, and to bring some relief from symptoms.

21 Sep 2012

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms, and the need for a lifetime of pain medications and blood transfusions. The researchers say the use of such marrow could potentially help make bone marrow transplants accessible to a majority of sickle cell patients who need them.

21 Sep 2012

NCI awards Provocative Questions grant to Mount Sinai School of Medicine researchers

Two Mount Sinai School of Medicine researchers are among a select group of scientists from around the world who have been recognized by the National Cancer Institute (NCI) for their quest to answer the most pressing questions about cancer. Stuart Aaronson, MD, Professor and Chair of Oncological Sciences and Ross Cagan, PhD, Professor of Oncological Sciences at Mount Sinai, have received the NCI's new "Provocative Questions" grant, which was established to explore the important yet less obvious questions about cancer that may have been neglected in this era of significant discovery.

21 Sep 2012

EMA CHMP adopts positive opinion for ELIQUIS to prevent stroke, systemic embolism in NVAF patients

Bristol-Myers Squibb and Pfizer Inc. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending that ELIQUIS (apixaban) be granted approval for the prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation (NVAF) and one or more risk factors for stroke.

21 Sep 2012

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

21 Sep 2012

Changing iv catheters only when necessary 'could benefit millions'

Peripheral intravenous catheters need be removed only when clinically indicated, rather than every 72 to 96 hours, as is currently recommended, conclude Australian researchers in findings that could have dramatic patient and cost benefits.

21 Sep 2012

Investigators identify two promising therapies to treat patients with acute megakaryocytic leukemia

Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is expected to increase with the aging population.

21 Sep 2012

Cedars-Sinai neurologist to study MS-related depression

Living every day with a life-changing illness is discouraging enough, but Maryam Hosseinzadeh is one of 400,000 people in the United States battling multiple sclerosis, a disorder that by changing the brain's makeup appears capable of generating the secondary ill of depression.

21 Sep 2012

MD Anderson introduces Moon Shots Program to reduce cancer deaths

The University of Texas MD Anderson Cancer Center announces the launch of the Moon Shots Program, an unprecedented effort to dramatically accelerate the pace of converting scientific discoveries into clinical advances that reduce cancer deaths.

21 Sep 2012

FDA approves Acton’s AEROSPAN sNDA to treat asthma

Acton Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved the sNDA (Supplemental New Drug Application) for AEROSPAN (flunisolide HFA, 80 mcg) Inhalation Aerosol, a hydrofluoroalkane (HFA) orally inhaled corticosteroid indicated for the maintenance treatment of asthma as a prophylactic therapy in adult and pediatric patients 6 years of age and older.

21 Sep 2012

St. Jude Medical’s Eon family of neurostimulators receives European CE Mark approval

St. Jude Medical, Inc., a global medical device company, today announced it has received European CE Mark approval of its Eon family of neurostimulators for patients with intractable chronic migraine. Unveiled at the European Headache and Migraine Trust International Congress in London, this approval includes the Eon Mini neurostimulator, which is the world's smallest rechargeable neurostimulator with the longest-lasting battery in its class, and the Eon and EonC neurostimulators.

21 Sep 2012

Hypertonic solution effective in reducing inflammation

Research carried out at The University of Manchester has found further evidence that a simple solution, which is already used in IV drips, is an effective treatment for reducing inflammation.

From The University of Manchester 21 Sep 2012

Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism

Cytochroma today announced the initiation of a phase 3 study of CTAP101 capsules in patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

21 Sep 2012

Benefits limited of surgery weight loss for sleep apnea

Obese patients with obstructive sleep apnea who lose significant weight through surgery may still not be cured of their sleep disorder, study findings indicate.

20 Sep 2012

Statin effect on thrombosis not so positive

Statins may not prevent venous thromboembolic events despite previous research suggesting otherwise, say researchers.

20 Sep 2012

Early menopause increases cardiovascular risk

Women who reach the menopause early have a doubled risk for coronary heart disease and stroke, study findings show.

20 Sep 2012

Close monitoring could give early warning of MS disease course

Patients with multiple sclerosis who have breakthrough disease activity early in the course of treatment with interferon beta-1a are at high risk for severe worsening and poor long-term outcomes, research shows.

20 Sep 2012

Recurrent glioblastoma: consider after effects before choosing palliative surgery

Before suggesting surgery as palliative therapy for patients with recurrent glioblastoma, physicians should consider the impact of morbidities on quality of life, suggest researchers from Italy.

20 Sep 2012

Institute for Translational Medicine and Therapeutics' 2012 symposium be held from Oct. 16-17

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) will be held October 16 and 17 at the Perelman School of Medicine, University of Pennsylvania.

20 Sep 2012

PNAS: Ras proteins bring tension to the phosphate chain

Proteins accelerate certain chemical reactions in cells by several orders of magnitude. The molecular mechanism by which the Ras protein accelerates the cleavage of the molecule GTP and thus slows cell growth is described by biophysicists at the Ruhr-Universit-t Bochum led by Prof. Dr. Klaus Gerwert in the Online Early Edition of the journal PNAS.

20 Sep 2012

Therapy News and Research

Adult stem cell therapy may benefit COPD patients

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

NCI awards Provocative Questions grant to Mount Sinai School of Medicine researchers

EMA CHMP adopts positive opinion for ELIQUIS to prevent stroke, systemic embolism in NVAF patients

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

Changing iv catheters only when necessary 'could benefit millions'

Investigators identify two promising therapies to treat patients with acute megakaryocytic leukemia

Cedars-Sinai neurologist to study MS-related depression

MD Anderson introduces Moon Shots Program to reduce cancer deaths

FDA approves Acton’s AEROSPAN sNDA to treat asthma

St. Jude Medical’s Eon family of neurostimulators receives European CE Mark approval

Hypertonic solution effective in reducing inflammation

Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism

Benefits limited of surgery weight loss for sleep apnea

Statin effect on thrombosis not so positive

Early menopause increases cardiovascular risk

Close monitoring could give early warning of MS disease course

Recurrent glioblastoma: consider after effects before choosing palliative surgery

Institute for Translational Medicine and Therapeutics' 2012 symposium be held from Oct. 16-17

PNAS: Ras proteins bring tension to the phosphate chain

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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