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Cedars-Sinai's ICT-107 doubles median survival of patients with malignant brain tumor

An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online Aug. 3.

16 Aug 2012

CYCLOPS genes may serve as targets for cancer therapies

The genomic tumult within tumor cells has provided scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard with clues to an entirely new class of genes that may serve as an Achilles' heel for many forms of cancer.

16 Aug 2012

Combination of exercise and S-nitrosoglutathione improves recovery from stroke

In a study published in the current issue of Restorative Neurology and Neuroscience scientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) improved recovery from stroke in a rat model. GSNO is a compound found naturally in the body and it has no known side effects or toxicity.

16 Aug 2012

UCLA performs first transcatheter aortic valve replacement using new device

UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place August 9th.

16 Aug 2012

Genocea commences GEN-003 Phase 1/2a study in moderate-to-severe HSV-2 infection

Genocea Biosciences announced today that it has initiated a Phase 1/2a clinical study with its lead candidate, GEN-003. GEN-003 is an investigational vaccine designed to stimulate T cell and B cell immune responses to potentially reduce the frequency and severity of clinical outbreaks associated with moderate-to-severe Herpes Simplex Virus type 2 (HSV-2) infection.

16 Aug 2012

Technion researchers build pancreatic tissue with insulin-secreting cells to treat diabetes

Technion researchers have built pancreatic tissue with insulin-secreting cells, surrounded by a three-dimensional network of blood vessels. The engineered tissue could pave the way for improved tissue transplants to treat diabetes.

16 Aug 2012

Cancer patients with xerostomia can benefit from regenerative research

Biologists, surgical oncologists and regenerative medicine specialists from Rice University, the University of Delaware and the Christiana Care Health System in Wilmington, Del., have begun a four-year program aimed at using cells to grow whole salivary glands that can replace those destroyed by cancer radiation therapy.

16 Aug 2012

Low HDL cholesterol ADVANCEs nephropathy risk in diabetes

People with diabetes are at a greater risk for the development or progression of diabetic nephropathy if they have low levels of high-density lipoprotein cholesterol, report researchers.

15 Aug 2012

Nurse-led HIV care benefits patients

Expansion of the role of primary care nurses to allow them to initiate and represcribe antiretroviral therapy to HIV patients improves health outcomes and quality of patient care, write researchers in The Lancet.

15 Aug 2012

Mechanism for chemotherapy resistance identified

Researchers have identified that chemotherapy induces subsequent treatment resistance through damaging healthy tissue, which in turn secretes novel factors that sustain the growth of residual tumor cells.

15 Aug 2012

Pediatric imatinib for Philadelphia-chromosome ALL fights relapse

Trial findings confirm the benefits of imatinib therapy in children with Philadelphia-chromosome-positive acute lymphoblastic leukemia.

15 Aug 2012

Short-term intervention alters neural architecture of stutterers

A short-term intervention in patients who stutter can help reorganize the intrinsic functional architecture of speech–language processes, a Chinese study shows.

15 Aug 2012

Therapeutic breaks for prostate cancer patients

Men with advanced prostate cancer receiving androgen-deprivation therapy may be better off being treated intermittently rather than on a continuous basis, show study findings.

15 Aug 2012

Couple therapy decreases PTSD symptoms and improves relationship

A North American study led by a researcher at Ryerson University has discovered that treating a person with posttraumatic stress disorder (PTSD) and their partner using a specific couple therapy greatly decreases the severity of their symptoms -- and improves their relationship.

15 Aug 2012

Infantile hemangiomas grow rapidly in babies much earlier than previously thought

Strawberry-shaped birthmarks called infantile hemangiomas grow rapidly in infants much earlier than previously thought, Mayo Clinic and University of California, San Francisco, researchers found.

15 Aug 2012

Novel device provides retina's neural code to restore normal vision

Two researchers at Weill Cornell Medical College have deciphered a mouse's retina's neural code and coupled this information to a novel prosthetic device to restore sight to blind mice.

15 Aug 2012

Kessler Foundation investigates Ekso's new capabilities for autonomous use by people with SCI

Kessler Foundation has begun testing the upgraded Ekso in individuals unable to walk due to spinal cord injury. Ekso, a wearable, battery-powered robotic exoskeletal device, has been undergoing clinical investigation at Kessler since October 2011, when the research team received the second commercial unit distributed by Ekso Bionics.

15 Aug 2012

Proteonomix receives FDA approval to commence UMK-121 Phase 1 trial in end-stage liver disease

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced that the U.S. Food and Drug Administration (FDA) has granted permission to the Company to initiate a Phase 1 clinical trial with its mobilization technology UMK-121.

15 Aug 2012

ADHD in girls portends continuing problems, through early adulthood

Girls with Attention Deficit Hyperactivity Disorder (ADHD) - and their families - often look forward to the likely decline in visible symptoms such as fidgety or disruptive behavior as they mature into young women.

15 Aug 2012

Early stage breast cancer in older women: an interview with Dr. Benjamin Smith

Early stage breast cancer in older women is a common problem. In the United States nearly half of women diagnosed with breast cancer are aged 65 or older. A sizeable proportion of those patients have early stage breast cancer.

15 Aug 2012