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AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

AbbVie, a global biopharmaceutical company, and Voyager Therapeutics, Inc., a clinical-stage gene therapy company, today announced that they have entered into an exclusive strategic collaboration and option agreement to develop and commercialize vectorized antibodies directed against tau for the treatment of Alzheimer's disease and other neurodegenerative diseases.

20 Feb 2018

Scientists develop water-soluble warped nanographene for bioimaging

An international team of scientists has developed a water-soluble "warped nanographene", a flexible molecule that is biocompatible and shows promise for fluorescent cell imaging.

19 Feb 2018

Nature paper unveils bacterial division

The process that allows bacteria to divide is crucial for their survival and a good target for the development of new antibiotics.

16 Feb 2018

Alternative MRI contrast agent shows promising results in NIH study

NIH-supported researchers at Massachusetts General Hospital are studying an alternative to the contrast agents currently used for magnetic resonance imaging.

14 Feb 2018

Scientists unravel immune cascade that drives tissue damage, complications in chlamydia infections

Closing a critical gap in knowledge, Harvard Medical School scientists have unraveled the immune cascade that fuels tissue damage and disease development in chlamydia infection - the most common sexually transmitted disease in the United States.

13 Feb 2018

Light-activated cancer drugs without toxic side effects are closer to becoming reality

Future cancer drugs that are activated by light and don't cause the toxic side-effects of current chemotherapy treatments are closer to becoming a reality, thanks to new research made possible by the Monash Warwick Alliance, an intercontinental collaboration between the University of Warwick and Monash University.

13 Feb 2018

Chemist finds how to control blood sugar without usual side effects

Chemist Robert Doyle in the College of Arts and Sciences at Syracuse University has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.

11 Feb 2018

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.

9 Feb 2018

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

A group of Brazilian scientists achieved promising results using isolated compounds from the venom of the South American rattlesnake in combat of hepatitis C.

8 Feb 2018

HDAC6 inhibition could be promising therapeutic approach for peripheral neuropathies

Inhibiting HDAC6 improves the structural stability of cells and protects against neuronal damage. Leuven research uncovered that targeting this mechanism could be a promising therapeutic approach for peripheral neuropathies, whether due to Charcot-Marie-Tooth disease (CMT) or as a side effect of chemotherapy.

8 Feb 2018

QUT researchers identify drug that could reverse brain deficits caused by alcohol

Queensland University of Technology researchers have identified a drug that could potentially help our brains reboot and reverse the damaging impacts of heavy alcohol consumption on regeneration of brain cells.

8 Feb 2018

First drug-candidate compounds discovered using AI licensed for development

Insilico Medicine, Inc., a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, announces that Juvenescence.AI, its joint venture with Juvenescence Limited, has licensed its first compound family for clinical development.

7 Feb 2018

Previously discarded antibiotic compounds could become life-saving drugs

Researchers are re-examining antibacterial compounds to see whether they could hold the key to fighting drug-resistant infections.

7 Feb 2018

UIC scientists identify new chemical compound to stop bacteria from causing sickness

A study published in the Journal of Biological Chemistry is the first to describe a signaling pathway that affects communication -- a process called quorum sensing -- between Streptococcus bacteria cells.

6 Feb 2018

Revolutionary technology could radically change cryopreservation of cells and tissues

Everyone knows that freezing things is an imperfect process. Take frozen food, for example - most have experienced those frozen ice crystals that change the texture and taste of their favorite meal.

6 Feb 2018

Researchers identify potential 'first-line' treatment for rare bone loss disease

A possible 'first-line' treatment for a rare bone loss disease has been identified by a research team led by Tohoku University in Japan. The research findings, published in the journal Molecular Cell, could also provide insight into treating age-related osteoporosis.

6 Feb 2018

Asynt’s DrySyn MAXI heating system used for reproducible scale-up of medicinal chemistry reactions

Asynt reports that medicinal chemistry specialists Charnwood Molecular (Loughborough UK) have been using the DrySyn MAXI heating system to successfully and reproducibly scale up syntheses within their contract research laboratories.

6 Feb 2018

Compounds derived from hops may improve cognitive, other functions in metabolic syndrome patients

A group of compounds derived from hops can likely improve cognitive and other functions in people with metabolic syndrome, new research at Oregon State University and Oregon Health & Science University suggests.

5 Feb 2018

Researchers use innovative method to screen kinases for cancer drug's effectiveness

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules bind with them.

5 Feb 2018

Researchers develop new method for producing personalized medicine

For the last 100 years, researchers have constantly pushed the boundaries for our knowledge about medicine and how different bodies can respond differently to it.

2 Feb 2018

Compound News and Research

AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

Scientists develop water-soluble warped nanographene for bioimaging

Nature paper unveils bacterial division

Alternative MRI contrast agent shows promising results in NIH study

Scientists unravel immune cascade that drives tissue damage, complications in chlamydia infections

Light-activated cancer drugs without toxic side effects are closer to becoming reality

Chemist finds how to control blood sugar without usual side effects

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

HDAC6 inhibition could be promising therapeutic approach for peripheral neuropathies

QUT researchers identify drug that could reverse brain deficits caused by alcohol

First drug-candidate compounds discovered using AI licensed for development

Previously discarded antibiotic compounds could become life-saving drugs

UIC scientists identify new chemical compound to stop bacteria from causing sickness

Revolutionary technology could radically change cryopreservation of cells and tissues

Researchers identify potential 'first-line' treatment for rare bone loss disease

Asynt’s DrySyn MAXI heating system used for reproducible scale-up of medicinal chemistry reactions

Compounds derived from hops may improve cognitive, other functions in metabolic syndrome patients

Researchers use innovative method to screen kinases for cancer drug's effectiveness

Researchers develop new method for producing personalized medicine

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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