Efficacy News and Research

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Repurposed drugs hold promise for targeting cancer stem cells

In a review published in the journal Genes & Diseases, researchers from ICMR-National Institute of Nutrition (NIN), advocate for the repurposing of non-cancer drugs to target these elusive CSCs.

22 Nov 2023

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Using oncolytic viruses (OVs) in combination with nanomaterials as a novel approach to cancer treatment.

22 Nov 2023

Sales of respiratory medications key to predicting disease mortality, UK study finds

The value of integrating national longitudinal shopping data into respiratory disease forecasting models.

22 Nov 2023

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility.

21 Nov 2023

St. Jude scientists discover potential CAR T cell therapy target for brain and solid tumors

Findings from St. Jude Children's Research Hospital are moving the field of cancer immunotherapy one step closer to treating brain and solid tumors.

21 Nov 2023

Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

21 Nov 2023

Immunotherapy drug is safe and may benefit overall survival for patients with advanced NSCLC

For patients with advanced or metastatic non-small cell lung cancer (NSCLC) and limited performance status, an immune checkpoint inhibitor drug called durvalumab is safe and may benefit overall survival, according to a new eClinicalMedicine study by UPMC Hillman Cancer Center researchers.

21 Nov 2023

Autism research needs more high-quality randomized studies, meta-analysis finds

A new meta-analysis led by Micheal Sandbank, PhD, an assistant professor in the Department of Health Sciences at the UNC School of Medicine, found that the field of autism needs more high-quality randomized studies of early interventions to help clinicians understand how to better support children diagnosed with the condition.

21 Nov 2023

Researchers discover new option to target the metastatic capacity of melanoma cells

As an extremely aggressive form of skin cancer, cutaneous melanoma is still associated with a high mortality rate. Enormous progress has recently been made in the fight against deadly metastasis, but existing therapeutic measures are still not effective in many cases.

21 Nov 2023

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Novel antidepressant zuranolone effective in alleviating depression and anxiety symptoms

The efficacy and safety of zuranolone in treating major depressive disorder (MDD).

20 Nov 2023

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (15 November 2023) extended the licence of the cystic fibrosis medicines Kaftrio (ivacaftor, tezacaftor and elexacaftor) and Kalydeco (ivacaftor) for children aged two to five years old.

20 Nov 2023

Innovative arts-literacy program shows promise in reducing youth depression and anxiety

A RCT to assess the efficacy of the Pre-Texts arts-literacy intervention in decreasing anxiety and depression among high school pupils.

20 Nov 2023

Breakthrough in tuberculosis treatment: TB-PRACTECAL trial reveals efficacy of new oral regimen

The TB-PRACTECAL clinical trial outcomes, which evaluated the efficacy and safety of oral bedaquiline.

20 Nov 2023

Simple soap solution could be a game-changer in the fight against malaria

Could the solution to the decades-long battle against malaria be as simple as soap? In a new study published in PLOS Neglected Tropical Diseases, scientists at The University of Texas at El Paso have made a compelling case for it.

17 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Green tea-silver nanoparticles: A promising weapon against superbugs

Once upon a time, people believed to be invincible against bacterial diseases, thanks to the antibiotics. Does this sound like a fairy tale? By all means! Nothing could be further from the truth.

17 Nov 2023

Immunogenicity of insect-specific Zika virus-vectorized vaccine candidates

The immunogenicity, safety, and effectiveness of ARPV/ZIKV a chimeric insect-specific flavivirus (ISFV)-Zika vaccine.

17 Nov 2023

AI-enhanced autism therapy: How multi-stage ensemble learning is changing the game By Pooja

Anticipating and identifying characteristics that impact or contribute to autism spectrum disorder therapy.

17 Nov 2023

Ketogenic diets and diabetes: A promising match or a questionable pair?

A recent research article in "Diabetes Therapy" examines the effectiveness of ketogenic diets in managing Type 1, Type 2, and gestational diabetes. Despite potential benefits like weight loss and improved glycemic control, the study highlights unresolved issues and the need for more extensive research before incorporating ketogenic diets into clinical guidelines for diabetes management.

16 Nov 2023

Efficacy News and Research

Repurposed drugs hold promise for targeting cancer stem cells

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Sales of respiratory medications key to predicting disease mortality, UK study finds

Study shows how probiotic Bifidobacteria longum can help relieve constipation

St. Jude scientists discover potential CAR T cell therapy target for brain and solid tumors

Scientists uncover key to enhancing cancer-killing T cells

Immunotherapy drug is safe and may benefit overall survival for patients with advanced NSCLC

Autism research needs more high-quality randomized studies, meta-analysis finds

Researchers discover new option to target the metastatic capacity of melanoma cells

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Novel antidepressant zuranolone effective in alleviating depression and anxiety symptoms

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

Innovative arts-literacy program shows promise in reducing youth depression and anxiety

Breakthrough in tuberculosis treatment: TB-PRACTECAL trial reveals efficacy of new oral regimen

Simple soap solution could be a game-changer in the fight against malaria

Unraveling the immune system's response to nanoparticle drug delivery

Green tea-silver nanoparticles: A promising weapon against superbugs

Immunogenicity of insect-specific Zika virus-vectorized vaccine candidates

AI-enhanced autism therapy: How multi-stage ensemble learning is changing the game By Pooja

Ketogenic diets and diabetes: A promising match or a questionable pair?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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