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Duke researchers identify first piece of new brain-repair circuit

Duke researchers have found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons. Though the experiments are in their early stages, the finding opens the tantalizing possibility that the brain may be able to repair itself from within.

3 Jun 2014

Ibrutinib outperforms ofatumumab as second-line therapy for CLL treatment

In a head-to-head comparison of two Food and Drug Administration-approved drugs for the treatment of relapsed chronic lymphocytic leukemia (CLL), ibrutinib significantly outperformed ofatumumab as a second-line therapy, according to a multicenter interim study published in the OnLine First edition of the New England Journal of Medicine.

2 Jun 2014

Eisai announces results from Phase III SELECT trial of lenvatinib evaluating PFS in patients with RR-DTC

Eisai Inc. announced today results from the Phase III SELECT trial of investigational agent lenvatinib evaluating progression-free survival (PFS) in patients with progressive radioiodine-refractory differentiated thyroid cancer (RR-DTC).

31 May 2014

Longer looks: 'Abandoning' patients; commiting people with mental illness; treating PTSD

For years I had tried and failed to understand why so many of my physician colleagues persisted in ordering tests, procedures, and treatments that seemed to provide no benefit to patients and even risked harming them.

30 May 2014

Study reveals how BTK mutation triggers drug resistance in CLL patients

A multi-institutional team of researchers has pinpointed exactly what goes wrong when chronic lymphocytic leukemia (CLL) patients develop resistance to ibrutinib, a highly effective, precisely targeted anti-cancer drug.

29 May 2014

New approach provides a viable way to culture hESCs for clinical purposes

To be suitable for medical transplantation, one idea is that human embryonic stem cells (hESCs) need to remain "undifferentiated" i.e. they are not changing into other cell types.

29 May 2014

Tai Chi intervention offers anti-aging benefits, says study

Tai Chi, a traditional Chinese martial art and sport, has been found to be beneficial in raising the numbers of an important type of cell when three groups of young people were tested to discover the benefits of Tai Chi, brisk walking or no exercise.

29 May 2014

Using brain during adolescence could help brain cells survive, says study

Using your brain - particularly during adolescence - may help brain cells survive and could impact how it functions after puberty.

28 May 2014

Commonly used diabetes medications may also have positive effects against cancer cell proliferation

One of the most commonly used medications to control diabetes may also have positive effects against cancer cell proliferation, as show in research done at the Center for Research and Advanced Studies (CINVESTAV) in Mexico.

28 May 2014

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.

26 May 2014

TSRI researchers discover key proteins involved in one type of DNA repair gone awry

Accumulation of DNA damage can cause aggressive forms of cancer and accelerated aging, so the body's DNA repair mechanisms are normally key to good health. However, in some diseases the DNA repair machinery can become harmful.

23 May 2014

MGH researchers test novel approach to disinfecting wounds in animal study

Application of a technology currently used to disinfect food products may help to get around one of the most challenging problems in medicine today, the proliferation of bacteria resistant to antibiotics and other antimicrobial drugs.

22 May 2014

Researchers discover key proteins involved in DNA repair gone awry

22 May 2014

Combination of metformin and rapamycin shows potential in treating aging and related diseases

A proven approach to slow the aging process is dietary restriction, but new research in the Linus Pauling Institute at Oregon State University helps explain the action of a drug that appears to mimic that process - rapamycin.

21 May 2014

Space Station science: Microgravity on human thyroid carcinoma cells

The multi-national efforts that go into research aboard the International Space Station show that working together can yield results with universal benefits.

21 May 2014

Researchers use mobile phone data to help combat malaria more effectively

An international study led by the University of Southampton and the National Vector-borne Diseases Control Programme (NVDCP) in Namibia has used mobile phone data to help combat malaria more effectively.

15 May 2014

C-section delivery, early antibiotic treatment linked to eosinophilic esophagitis in children

Children delivered by cesarean section and those given antibiotics during early infancy appear more prone to developing allergic inflammation of the esophagus — the muscular tube that connects the mouth to the stomach — according to results of a study by investigators from the Johns Hopkins Children’s Center and Harvard Medical School.

13 May 2014

Regular grape consumption may help alleviate pain linked with symptomatic osteoarthritis of knee

New research presented last week at the Experimental Biology conference in San Diego, California, suggests that regular grape consumption may help alleviate pain associated with symptomatic osteoarthritis of the knee, and improve joint flexibility and overall mobility.

12 May 2014

Single-cell genomics study confirms that immune cells produce steroids

Researchers at the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute have discovered that some immune cells turn themselves off by producing a steroid.

9 May 2014

Study finds ovarian cancer cells are more aggressive on soft tissues due to mechanical properties of environment

When ovarian cancer spreads from the ovaries it almost always does so to a layer of fatty tissue that lines the gut.

9 May 2014

Proliferation News and Research

Duke researchers identify first piece of new brain-repair circuit

Ibrutinib outperforms ofatumumab as second-line therapy for CLL treatment

Eisai announces results from Phase III SELECT trial of lenvatinib evaluating PFS in patients with RR-DTC

Longer looks: 'Abandoning' patients; commiting people with mental illness; treating PTSD

Study reveals how BTK mutation triggers drug resistance in CLL patients

New approach provides a viable way to culture hESCs for clinical purposes

Tai Chi intervention offers anti-aging benefits, says study

Using brain during adolescence could help brain cells survive, says study

Commonly used diabetes medications may also have positive effects against cancer cell proliferation

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

TSRI researchers discover key proteins involved in one type of DNA repair gone awry

MGH researchers test novel approach to disinfecting wounds in animal study

Researchers discover key proteins involved in DNA repair gone awry

Combination of metformin and rapamycin shows potential in treating aging and related diseases

Space Station science: Microgravity on human thyroid carcinoma cells

Researchers use mobile phone data to help combat malaria more effectively

C-section delivery, early antibiotic treatment linked to eosinophilic esophagitis in children

Regular grape consumption may help alleviate pain linked with symptomatic osteoarthritis of knee

Single-cell genomics study confirms that immune cells produce steroids

Study finds ovarian cancer cells are more aggressive on soft tissues due to mechanical properties of environment

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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