Chronic Disease News and Research

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Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

AHIP, BCBS say insurers willing to stop basing premiums on members' health status if all U.S. residents are required to obtain coverage

In a letter to leaders of the Senate Finance Committee and the Senate Health, Education, Labor and Pensions Committees on Tuesday, America's Health Insurance Plans and the BlueCross BlueShield Association said that their memberships would be willing to end the practice of charging different premiums based on individuals' health status if all U.S. residents were required to obtain coverage, CongressDaily reports (Edney, CongressDaily, 3/25).

25 Mar 2009

Red and processed meat linked to greater risk of death from all causes

Individuals who eat more red meat and processed meat appear to have a modestly increased risk of death from all causes and also from cancer or heart disease over a 10-year period, according to a report in the March 23 issue of Archives of Internal Medicine.

23 Mar 2009

On demand doctor's appointments do not improve diabetes care

Same-day medical scheduling, also known as on demand scheduling, does not improve care of chronically ill individuals, according to a study of 4,060 adult patients with diabetes.

23 Mar 2009

Research could lead to potential new drugs for treating asthma

The American Asthma Foundation announced that a significant research discovery they funded has been licensed by a leading biotech company.

20 Mar 2009

Research shows strong links between mothers' diets and the health of their children

A new report by University of Southampton academics emphasises the links between poor diet in mothers and ill-health in their children, and calls for women of childbearing age to be made more aware of the importance of good nutrition.

16 Mar 2009

'Seeing' stem cells helps in fight against peripheral arterial disease

Interventional radiologists are fitting together the puzzle pieces of how to use stem cells to create new or more blood vessels to treat peripheral arterial disease (PAD) in those individuals with extensively narrowed or clogged arteries.

11 Mar 2009

Helium/oxygen mix helps lung patients breathe easier

New research published in the international journal Chest , by Neil Eves, PhD, finds that people with chronic obstructive pulmonary disease (COPD) who breathed a mix of 60% helium and 40% oxygen during a rehabilitation program were able to exercise longer and harder than those who breathed normal air.

10 Mar 2009

Diabetes linked to cognitive deterioration

Blindness, renal failure, stroke and heart disease are potential complications of type 2 diabetes, which currently afflicts more than 15 million Americans.

5 Mar 2009

Emerging therapies could ease symptoms of Atopic dermatitis

Atopic dermatitis, the common, chronic, inflammatory skin disease marked by red, itchy rashes, has been increasing in prevalence over the past two decades and affects a disproportionate number of children.

5 Mar 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers at Wake Forest University Baptist Medical Center, and colleagues, have identified a gene that modifies the severity of lung disease in people with cystic fibrosis, a lethal genetic condition. The findings open the door to possible new targets for treatment, researchers say.

3 Mar 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers have discovered a gene that modifies the severity of lung disease in people with the lethal genetic condition, cystic fibrosis, pointing to possible new targets for treatment, according to a new study in Nature.

25 Feb 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

25 Feb 2009

Children with hypertension have trouble with goal-directed tasks

Children with high blood pressure are not as good at complicated, goal-directed tasks, have more working memory problems and are not as adept at planning as their peers without hypertension, according to recent research.

24 Feb 2009

FDA issues warning on psoriasis drug Raptiva (efalizumab)

The U.S. Food and Drug Administration has issued a public health advisory concerning three confirmed, and one possible report of progressive multifocal leukoencephalopathy (PML), a rare brain infection, in patients using the psoriasis drug Raptiva (efalizumab).

20 Feb 2009

Opportunities for the health system in a sick economy

With the interim report of the National Health and Hospitals Reform Commission published yesterday the time for implementing reform could hardly be better.

18 Feb 2009

Researchers show how immune system reacts to a hepatitis B infection

Researchers at the Helmholtz Centre in Braunschweig demonstrate how the immune system reacts to a hepatitis B infection.

17 Feb 2009

Most coordinated care programs for Medicare beneficiaries do not show benefit

Only 2 of 15 Medicare programs designed to improve care and costs for patients with chronic illnesses resulted in reduced hospital admissions, and none of the programs generated net savings, according to a study in the February 11 issue of JAMA.

10 Feb 2009

Multivitamin use not linked to women's risk of cancer, heart disease or death

Postmenopausal women who take multivitamins appear to have the same risk of most common cancers, cardiovascular disease or dying of any cause as women who do not take multivitamin supplements, according to a report in the February 9 issue of Archives of Internal Medicine.

9 Feb 2009

Australia in need of a complete food-policy overhaul

The report by the Public Health Association of Australia (PHAA) says that the only way to effectively address the priorities of chronic disease prevention, climate change and social inequality is by a complete overhaul of food policy in Australia.

2 Feb 2009