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Researchers identify a previously unknown mitochondrial disease in identical twins

In a set of identical twins, investigators led by researchers at Massachusetts General Hospital (MGH) and Children's Hospital Philadelphia (CHOP) have identified a mitochondrial disease not previously reported.

14 Oct 2022

Study describes the first SARS-CoV-2 Deltacron recombinant case identified in Brazil

Researchers demonstrated the parallel evolution of the SARS-CoV-2 Deltacron variant.

14 Oct 2022

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a leading infectious threat to public health worldwide.

13 Oct 2022

DTU researchers create a new tool in the fight against resistant bacteria

According to the WHO, antibiotic resistance is one of the biggest threats to public health. DTU researchers have created a new tool in the fight against resistant bacteria that, based on 214,000 microbiome samples, can create an overview of the problem across countries, people and environments.

13 Oct 2022

Largest academic collaboration aims to transform the treatment for pediatric cancers

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children's Research Hospital today announced the largest academic collaboration of its kind to transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into better treatments.

13 Oct 2022

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

In a new study, researchers visualized the mechanism of action and inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 13 (NSP13) at high spatio-temporal resolution.

13 Oct 2022

UQ-led study analyzes genetic variants that influence height

Children's growth will be easier to assess following a University of Queensland-led study analyzing the genetic variants that influence height.

12 Oct 2022

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers developed a RT-qPCR system to identify SARS-CoV-2 Omicron variants of concern.

12 Oct 2022

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Scientists have identified a handful of gene mutations that cause or contribute to the onset of Alzheimer's disease.

11 Oct 2022

Two new studies help improve the understanding of ovarian cancer

Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women's tumors do not respond to therapy.

11 Oct 2022

Mismatches in the primer and probe sequences of current Monkeypox virus diagnostic assays require rectification to improve detection accuracy

Researchers analyzed the primer and probe sequences of the United States Centers for Disease Control and Prevention (CDC) recommended monkeypox virus (MPXV) generic real-time polymerase chain reaction (PCR) assays.

11 Oct 2022

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins.

11 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Researchers explored the role of the ORF3c, a SARS-CoV-2 accessory protein not so extensively studied as yet.

7 Oct 2022

Genome News and Research

Researchers identify a previously unknown mitochondrial disease in identical twins

Study describes the first SARS-CoV-2 Deltacron recombinant case identified in Brazil

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

DTU researchers create a new tool in the fight against resistant bacteria

Largest academic collaboration aims to transform the treatment for pediatric cancers

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

UQ-led study analyzes genetic variants that influence height

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Two new studies help improve the understanding of ovarian cancer

Mismatches in the primer and probe sequences of current Monkeypox virus diagnostic assays require rectification to improve detection accuracy

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

Zinc could improve the brain defects caused by rare genetic disorder

NEI researchers create a high-resolution map of retinal cell chromatin contract points

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

Researchers take new approach to studying the development of the human brain

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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