Proliferation News and Research

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Noroviruses responsible for almost a fifth of all cases of acute gastroenteritis

Noroviruses are a leading cause of acute gastroenteritis (diarrhoea and vomiting) across all age groups, responsible for almost a fifth (18%) of all cases worldwide. New estimates, published in The Lancet Infectious Diseases, highlight the importance of developing norovirus vaccines, say the authors.

27 Jun 2014

FDA grants Encision 510(k) approval for AEM Endoshield Burn Protection System

Encision Inc., a medical device company owning patented surgical technology that prevents dangerous stray electrosurgical burns in minimally invasive surgery, today announced that it has received FDA 510(k) premarket notification approval for its AEM Endoshield™ Burn Protection System ("EndoShield").

27 Jun 2014

Study explains why people with disrupted circadian rhythms can be more susceptible to cancer

Research led by the University of Warwick's Systems Biology Centre and Medical School in collaboration with groups in Nice and Rotterdam has been able to demonstrate how the cycle of cell division in mammalian cells synchronises with the body's own daily rhythm, its circadian clock.

26 Jun 2014

BPA appears to increase proliferation of breast cancer cells, diminish effectiveness of treatments

Bisphenol A (BPA), a chemical commonly used in plastics, appears to increase the proliferation of breast cancer cells, according to Duke Medicine researchers presenting at an annual meeting of endocrine scientists.

23 Jun 2014

UCLA study sheds light on the development of lung cancer

UCLA researchers led by Dr. Brigitte Gomperts have discovered the inner workings of the process thought to be the first stage in the development of lung cancer. Their study explains how factors that regulate the growth of adult stem cells that repair tissue in the lungs can lead to the formation of precancerous lesions.

20 Jun 2014

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

20 Jun 2014

Researchers identify new mechanism by which normal cells turn malignant in mammary epithelial tissues

A team of researchers led by David J. Mooney, Robert P. Pinkas Family Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences, have identified a possible mechanism by which normal cells turn malignant in mammary epithelial tissues, the tissues frequently involved in breast cancer.

17 Jun 2014

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Advanced online publication in Nature: Researchers at the Université libre de Bruxelles, ULB uncover the molecular mechanisms regulating tumour initiation and cancer stem cells functions in skin squamous cell carcinoma.

11 Jun 2014

Celsion signs definitive asset purchase agreement to acquire EGEN

Celsion Corporation (Celsion) (NASDAQ: CLSN), an oncology drug development company, and EGEN, Inc. (EGEN), a privately-held biopharmaceutical company focused on the development of nucleic acid-based therapeutics for the treatment of cancer and other difficult to treat diseases, today announced the signing of a definitive asset purchase agreement in which Celsion will acquire substantially all of the assets of EGEN, including its Phase Ib DNA-based immunotherapy product candidate EGEN-001 and its therapeutic platform technologies, TheraPlas™ for delivery of DNA and mRNA, TheraSilence™ for delivery of RNA, and RAST™ for Cell Enabled Expression and Secretion of RNA.

10 Jun 2014

JDRF-funded researchers find that beta cell stress may play vital role in the onset of type 1 diabetes

In the healthy pancreas of someone without type 1 diabetes (T1D), the hormone insulin (essential for turning food into energy) is produced, stored, and released in a normal "factory-like" process within pancreatic beta cells in response to glucose in the diet.

10 Jun 2014

Study sheds light on new potential treatment for heat stroke

Scientists in Taiwan have found that intravenous injections of stem cells derived from human exfoliated deciduous tooth pulp (SHED) have a protective effect against brain damage from heat stroke in mice. Their finding was safe and effective and so may be a candidate for successfully treating human patients by preventing the neurological damage caused by heat stroke.

6 Jun 2014

Biomarkers help resolve differential diagnosis between MPM and non-cancerous pleural tissue

Scientists have identified four biomarkers that may help resolve the difficult differential diagnosis between malignant pleural mesothelioma (MPM) and non-cancerous pleural tissue with reactive mesothelial proliferations (RMPs).

6 Jun 2014

Duke researchers identify first piece of new brain-repair circuit

Duke researchers have found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons. Though the experiments are in their early stages, the finding opens the tantalizing possibility that the brain may be able to repair itself from within.

3 Jun 2014

Ibrutinib outperforms ofatumumab as second-line therapy for CLL treatment

In a head-to-head comparison of two Food and Drug Administration-approved drugs for the treatment of relapsed chronic lymphocytic leukemia (CLL), ibrutinib significantly outperformed ofatumumab as a second-line therapy, according to a multicenter interim study published in the OnLine First edition of the New England Journal of Medicine.

2 Jun 2014

Proliferation News and Research

Noroviruses responsible for almost a fifth of all cases of acute gastroenteritis

FDA grants Encision 510(k) approval for AEM Endoshield Burn Protection System

Study explains why people with disrupted circadian rhythms can be more susceptible to cancer

BPA appears to increase proliferation of breast cancer cells, diminish effectiveness of treatments

UCLA study sheds light on the development of lung cancer

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Researchers identify new mechanism by which normal cells turn malignant in mammary epithelial tissues

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Celsion signs definitive asset purchase agreement to acquire EGEN

JDRF-funded researchers find that beta cell stress may play vital role in the onset of type 1 diabetes

Study sheds light on new potential treatment for heat stroke

Biomarkers help resolve differential diagnosis between MPM and non-cancerous pleural tissue

Duke researchers identify first piece of new brain-repair circuit

Ibrutinib outperforms ofatumumab as second-line therapy for CLL treatment

Eisai announces results from Phase III SELECT trial of lenvatinib evaluating PFS in patients with RR-DTC

Longer looks: 'Abandoning' patients; commiting people with mental illness; treating PTSD

Study reveals how BTK mutation triggers drug resistance in CLL patients

New approach provides a viable way to culture hESCs for clinical purposes

Tai Chi intervention offers anti-aging benefits, says study

Using brain during adolescence could help brain cells survive, says study

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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