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XJB-5-131 prevents secondary damage of severe traumatic brain injury

Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience.

27 Aug 2012

Study confirms electrical storm as potent risk factor for death and impaired quality of life

Electrical storm (ES) is a potent risk factor for mortality and morbidity, according to research presented today at the ESC Congress 2012 by Dr Federico Guerra from Italy. Data was also presented on which patients are prone to developing ES and how effective current treatments are.

27 Aug 2012

Study: Lower use of drug eluting stents in women treated with PCI than men

Drug eluting stents (DES) are used less often in women treated with percutaneous coronary intervention (PCI) for coronary artery disease than men treated with PCI for the same condition, according to research presented today at the ESC Congress 2012.

27 Aug 2012

Female sex associated with increased risk of stroke for AF patients aged ≥75 years

Female gender increases the risk of stroke in patients with atrial fibrillation (AF) aged >75 years by 20%, according to a study presented today at the ESC Congress 2012. The findings were presented by Anders Mikkelsen, from Denmark.

27 Aug 2012

Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer

ImmunoGen, Inc., a biotechnology company that develops anticancer products using its Targeted Antibody Payload (TAP) technology and antibody expertise, today announced that Roche has reported that updated results from its EMILIA Phase III trial show that patients treated with trastuzumab emtansine had a significant improvement in OS compared to those randomized to standard-of-care therapy.

27 Aug 2012

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs - prasugrel and clopidogrel - in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists.

27 Aug 2012

Patients tend to have worse outcomes when GBM appears in more than one location

When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts as a single tumor, even though patients in both groups undergo virtually identical treatments, according to research at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Research Institute.

27 Aug 2012

SUMO1 protein may treat and/or prevent heart failure

A promising new drug target for the treatment and prevention of heart failure has been discovered by researchers at Mount Sinai School of Medicine in New York, NY, US. The study was presented at the ESC Congress 2012 by principal investigator Professor Roger J. Hajjar, MD.

26 Aug 2012

American Physical Therapy Association to host series on concussion in sports

As football season gets under way, the American Physical Therapy Association (APTA) will host a series on concussion in sports called "Head in the Game."

26 Aug 2012

Dominican Republic establishes commission to examine implications of including ART in country health plan

"The Dominican Republic is one step closer to ensuring that all people living with HIV access treatment," UNAIDS reports in an article on its webpage, adding, "The country's National Social Security Council has established a commission to look into the technical, financial and operational implications of including antiretroviral therapy (ART) in the Basic Health Plan."

26 Aug 2012

Parachute device improves outcomes in patients with ischemic heart failure

A novel non-invasive device which separates healthy and damaged heart muscle and restores ventricle function improves 3 year outcomes in patients with ischemic heart failure, according to research presented at the ESC Congress 2012.

26 Aug 2012

Personalized colon cancer therapy based on genetics of specific cancer

University of Minnesota Medical School and Masonic Cancer Center researchers have partnered with geneticists from Genentech, Inc., to discover how some proteins may cause the development of some forms of colon cancers.

24 Aug 2012

Understanding photoreceptor proteins could lead to cancer drug therapy

How does a plant know when to sprout a leaf, fold its petals or bloom? Why do humans experience jet lag after a trip abroad?

24 Aug 2012

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Seattle Genetics, Inc. today announced the initiation of a phase Ib clinical trial evaluating SGN-75 in combination with everolimus (Afinitor) for patients with advanced metastatic renal cell carcinoma (RCC).

24 Aug 2012

Statins reduce pancreatitis risk

Statins reduce the risk for pancreatitis in patients with normal or mildly elevated triglyceride levels, say the authors of a large meta-analysis.

24 Aug 2012

HIV-like immunodeficiency observed in Asia

Researchers have discovered an adult-onset immunodeficiency syndrome with symptoms similar to those of advanced HIV in Thailand and Taiwan.

24 Aug 2012

Radiating fears over diabetes in childhood cancer survivors

People who undergo pancreatic irradiation during childhood cancer therapy are at an increased risk for developing diabetes later in life, report researchers.

24 Aug 2012

Novira secures $23M in Series A financing to support antiviral development for HBV, HIV

Novira Therapeutics Inc. today announced it has secured $23 million in Series A financing to support the development of its capsid-targeting antivirals for the treatment of chronic hepatitis B (HBV) and HIV infections.

24 Aug 2012

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Waiting to treat the commonest viral infections in transplant recipients until they reach a certain threshold is better than prophylactically treating all recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

24 Aug 2012

Diabetes journal reports results from novel experimental therapy

Results from a novel experimental therapy for Type 1 diabetes that boosts parts of the healthy immune system are reported today in the scientific journal Diabetes.

24 Aug 2012

Therapy News and Research

XJB-5-131 prevents secondary damage of severe traumatic brain injury

Study confirms electrical storm as potent risk factor for death and impaired quality of life

Study: Lower use of drug eluting stents in women treated with PCI than men

Female sex associated with increased risk of stroke for AF patients aged ≥75 years

Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

Patients tend to have worse outcomes when GBM appears in more than one location

SUMO1 protein may treat and/or prevent heart failure

American Physical Therapy Association to host series on concussion in sports

Dominican Republic establishes commission to examine implications of including ART in country health plan

Parachute device improves outcomes in patients with ischemic heart failure

Personalized colon cancer therapy based on genetics of specific cancer

Understanding photoreceptor proteins could lead to cancer drug therapy

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Statins reduce pancreatitis risk

HIV-like immunodeficiency observed in Asia

Radiating fears over diabetes in childhood cancer survivors

Novira secures $23M in Series A financing to support antiviral development for HBV, HIV

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Diabetes journal reports results from novel experimental therapy

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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