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Early surgery best for infective endocarditis

Compared with conventional treatment, early surgery for patients with infective endocarditis and large vegetations significantly reduces the risk for death or embolic events by reducing the risk for systemic embolism, show results from a randomized trial.

12 Jul 2012

Opioids for chronic noncancer pain discouraged

US experts have called for more selective and cautious opioid prescribing for chronic noncancer pain, because of concerns over misuse of the drugs and continued uncertainty over when and for how long they should be prescribed.

12 Jul 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

Mayo Clinic, 18 other leading research institutions urge Congress to maintain funding levels for NIH

Mayo Clinic and 18 other leading medical research institutions nationwide are urging congressional leaders to maintain current funding levels for the National Institutes of Health.

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

Nonsurgical treatment may be more beneficial for baseball players with SLAP tears

Surgically repairing a painful shoulder injury in baseball players known as a SLAP tear (superior labral) varies widely and often doesn't allow for return to play at the same level as before the injury. However, researchers presenting their findings at the American Orthopaedic Society for Sports Medicine's Annual Meeting in Baltimore, Maryland suggest that nonsurgical treatment may be more beneficial.

12 Jul 2012

Low-fat, high fruit and vegetable diet may help reduce menopausal symptoms

Weight loss that occurs in conjunction with a low-fat, high fruit and vegetable diet may help to reduce or eliminate hot flashes and night sweats associated with menopause, according to a Kaiser Permanente Division of Research study that appears in the current issue of Menopause.

12 Jul 2012

Eschar-derived cells may be used for tissue engineering

A research team in the Netherlands has found that cells from burn eschar, the non-viable tissue remaining after burn injury and normally removed to prevent infection, can be a source of mesenchymal cells that may be used for tissue engineering.

12 Jul 2012

Physiologists, neuropathologists identify origin of cancer metastasis formation

It is not primary tumors that are responsible for the majority of cancer deaths, but rather their metastases. Physiologists and neuropathologists from the University of Zurich have now identified the origin of metastasis formation, thereby becoming the first to reveal the pathway of metastasizing intestinal cancer cells out of the blood stream. The results allow new approaches in the development of cancer therapies.

12 Jul 2012

Mindfulness techniques show health benefits

Specific types of "mindfulness practices" including Zen meditation have research-proven benefits for patients with certain physical and mental health problems, according to a report in the July Journal of Psychiatric Practice.

12 Jul 2012

Study details how resistance to targeted drug therapy emerges in colorectal cancers

A Harvard researcher studying the evolution of drug resistance in cancer is predicting that, in a few decades, "many, many cancers could be manageable."

12 Jul 2012

New book outlines cutting-edge approach to systematically address AD

ADEC Inc. - Worried about your memory? Many patients with Alzheimer's disease (AD) and individuals concerned about developing memory loss feel they have limited options. While there is no 'magic pill' to cure or prevent AD, a new book outlines a cutting-edge approach to systematically address this disease.

12 Jul 2012

BioControl Medical receives FDA approval to initiate second phase of CardioFit study for heart failure

BioControl Medical has announced U.S. Food and Drug Administration approval to begin the second phase of INOVATE-HF (INcrease Of VAgal TonE in Heart Failure), a global, multi-center, investigational device exemption (IDE) clinical study of the company's CardioFit system for heart failure.

12 Jul 2012

NOXXON commences Spiegelmer NOX-A12 Phase IIa trial in CLL

NOXXON Pharma today announced the treatment of the first cohort of three chronic lymphocytic leukemia (CLL) patients in a Phase IIa clinical trial of its NOX-A12 anti-CXCL12/SDF-1 (CXC Chemokine Ligand 12 / Stromal Cell-Derived Factor-1) Spiegelmer.

12 Jul 2012

Man Therapy launches in Colorado

Man Therapy, a groundbreaking new approach to suicide prevention and other men's mental health issues, was launched in Colorado today. Man Therapy reshapes the conversation, using humor to cut through stigma and tackle issues like depression, divorce and even suicidal thoughts head on, the way a man would do it.

12 Jul 2012

Enrollment complete in Phase III IND study of Spinal Restoration's Biostat System

Spinal Restoration, Inc. announced today the completion of enrollment in the Phase III Investigational New Drug (IND) study of the Biostat System. The Phase III clinical trial is a 260-subject, randomized, blinded, placebo controlled study designed to assess the ability of the Biostat System to reduce pain and improve function in patients with chronic discogenic low back pain.

12 Jul 2012

Pain rehab may boost children’s ownership of self management

Pediatric pain rehabilitation may lead to an increased willingness to self-manage pain, which is associated with improvements in function and psychologic wellbeing, say researchers.

11 Jul 2012

Oligodendroglia cells: An interview with Jeffrey Rothstein

There are three principle cells in the brain: neurons and two types of glial cells. One type is called an astrocyte. These were well known to inactivate neurotransmitters like glutamate, and provide metabolic support to neurons.

11 Jul 2012

OncoSec establishes UCSF as second enrolling site for OMS-I110 Phase II Merkel cell carcinoma trial

OncoSec Medical Inc., a company developing the advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumors, announces it has established the University of California San Francisco (UCSF) as the second enrolling site for its Phase II Merkel cell carcinoma clinical trial (OMS-I110).

11 Jul 2012

Therapy News and Research

Early surgery best for infective endocarditis

Opioids for chronic noncancer pain discouraged

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

Mayo Clinic, 18 other leading research institutions urge Congress to maintain funding levels for NIH

Communication between brain and muscle cells is short-lived without LRP4 protein

Nonsurgical treatment may be more beneficial for baseball players with SLAP tears

Low-fat, high fruit and vegetable diet may help reduce menopausal symptoms

Eschar-derived cells may be used for tissue engineering

Physiologists, neuropathologists identify origin of cancer metastasis formation

Mindfulness techniques show health benefits

Study details how resistance to targeted drug therapy emerges in colorectal cancers

New book outlines cutting-edge approach to systematically address AD

BioControl Medical receives FDA approval to initiate second phase of CardioFit study for heart failure

NOXXON commences Spiegelmer NOX-A12 Phase IIa trial in CLL

Man Therapy launches in Colorado

Enrollment complete in Phase III IND study of Spinal Restoration's Biostat System

Pain rehab may boost children’s ownership of self management

Oligodendroglia cells: An interview with Jeffrey Rothstein

OncoSec establishes UCSF as second enrolling site for OMS-I110 Phase II Merkel cell carcinoma trial

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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