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Study demonstrates effectiveness of combination therapy for breast cancer cells in vitro

A study conducted at Boston University School of Medicine (BUSM) demonstrates an effective combination therapy for breast cancer cells in vitro.

3 Jul 2012

Muhammad Ali Parkinson Center receives $3M donation from Celebrity Fight Night

The Muhammad Ali Parkinson Center at St. Joseph's Hospital and Medical Center in Phoenix has received a $3 million donation from Celebrity Fight Night that will be used to help dramatically expand the renowned facility and its programs.

3 Jul 2012

Heart attacks that occur in late pregnancy cause more damage

Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.

3 Jul 2012

Study examines prevalence of pain among HIV patients in two Ugandan outpatient sites

Sub-Saharan Africa accounts for 69 percent of HIV cases worldwide and 72 percent of AIDS deaths. A study published in The Journal of Pain showed that pain is highly prevalent among well functioning HIV patients in Africa, has a debilitating impact of quality of life, and there is a significant level of unmet need for pain relief.

3 Jul 2012

Sun exposure advice recommended for anti-TNF users

Rheumatology patients using antitumor necrosis factor treatment should be given sun exposure education to reduce their risk for skin cancer, say Irish researchers.

2 Jul 2012

Fighting the physical consequences of jet lag in elite athletes

Research suggests that having a good understanding of preflight, in-flight, and postflight management options helps clinicians, athletes, and coaches minimize the adverse consequences of travel fatigue and jet lag on elite athletic performance.

2 Jul 2012

Obese women draw the hypertension short straw

The associations of obesity with prehypertension and hypertension are stronger in women than men, a study suggests.

2 Jul 2012

Routine use of pelvic CT scans in Wilms tumor questioned

Omitting pelvic computed tomography scans from the routine surveillance of off-therapy patients with Wilms tumor could reduce radiation exposure without compromising relapse detection rates, researchers report.

2 Jul 2012

Three-step clinical pathway for CAP reduces length of hospital stay

A three-step pathway helps to reduce the duration of intravenous antibiotic treatment in hospitalized patients with community-acquired pneumonia, show study findings published in the Archives of Internal Medicine.

2 Jul 2012

Vitamin D–calcium combo reduces mortality in elderly

The results of a meta-analysis of individual patient data show that vitamin D supplementation with calcium reduces mortality rates in the elderly.

2 Jul 2012

Prostate Cancer Center of New Jersey earns ACR-ASTRO accreditation in radiation oncology

The Prostate Cancer Center of New Jersey, a partnership between AKSM/Oncology and the Urology Group of New Jersey (UGNJ), is the latest in a rapidly growing list of prostate-only treatment centers to earn the high honor of a three-year term of accreditation in radiation oncology.

2 Jul 2012

Onyx commences ENDEAVOR Kyprolis Phase 3 trial for relapsed multiple myeloma

Onyx Pharmaceuticals, Inc. announced today that the company has begun enrollment in the ENDEAVOR trial, a Phase 3 trial evaluating Kyprolis in combination with dexamethasone, versus bortezomib with dexamethasone in patients with relapsed multiple myeloma.

2 Jul 2012

Current diagnosis and treatment approaches for rheumatoid arthritis

In the realm of deadly and disabling diseases, conditions such as cancer and Alzheimer's seem to attract the most media attention. But there are others that take a similarly high toll, and rheumatoid arthritis is one of them, Mayo Clinic researchers say. It is a common cause of disability: 1 of every 5 rheumatoid arthritis patients is unable to work two years after diagnosis, and within five years, that rises to one-third. Life expectancy drops by up to five years.

2 Jul 2012

Cerulean commences dosing in CRLX101-Avastin combination study for metastatic renal cell carcinoma

Cerulean Pharma Inc., a leader in developing dynamically tumor-targeted nanopharmaceuticals, today announced that the first patient has been dosed in a Phase 1b/2a study of its lead product candidate, CRLX101, in combination with Avastin, in metastatic renal cell carcinoma (mRCC) patients. The company also announced the completion of enrollment of its randomized Phase 2 study in advanced non-small cell lung cancer.

2 Jul 2012

Enrollment complete in Cerulean CRLX101 Phase 2 study for non-small cell lung cancer

Cerulean Pharma Inc., a leader in developing dynamically tumor-targeted nanopharmaceuticals, today announced that it has completed enrollment of a randomized Phase 2 study of its lead candidate, CRLX101, in advanced non-small cell lung cancer (NSCLC). The company also announced that it has dosed the first patient in a second tumor type.

2 Jul 2012

Pediatric pain still common in hospitals

Despite advances in the understanding and treatment of pediatric pain, many hospitalized children continue to experience serious pain, according to a Johns Hopkins Children’s Center study published online ahead of print in the journal Pain Management Nursing.

2 Jul 2012

Transcranial direct current stimulation can enhance outcome of swallowing therapy for post-stroke dysphagia

After stroke, patients often suffer from dysphagia, a swallowing disorder that results in greater healthcare costs and higher rates of complications such as dehydration, malnutrition, and pneumonia.

2 Jul 2012

Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB

Janssen Research & Development, LLC today announced it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking accelerated approval for the use of the investigational drug bedaquiline (TMC207) as an oral treatment, to be used as part of combination therapy for pulmonary, multi-drug resistant tuberculosis (MDR-TB) in adults.

2 Jul 2012

CytRx granted European patent for tumor-targeting linker platform technology

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced that the European Patent Office (EPO) has issued a patent covering the Company's tumor-targeting linker platform technology and pharmaceutical compositions.

2 Jul 2012

Safer alternative to experimental gene therapy against HIV infection

Scientists at The Scripps Research Institute have discovered a surprisingly simple and safe method to disrupt specific genes within cells. The scientists highlighted the medical potential of the new technique by demonstrating its use as a safer alternative to an experimental gene therapy against HIV infection.

2 Jul 2012