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Scientists discover biological marker that may help identify patients’ response to antidepressants

Scientists have discovered a biological marker that may help to identify which depressed patients will respond to an experimental, rapid-acting antidepressant. The brain signal, detectable by noninvasive imaging, also holds clues to the agent's underlying mechanism, which are vital for drug development, say National Institutes of Health researchers.

7 Aug 2012

Blood levels of IL-6 protein may also serve as red flag for relapse in schizophrenia patients

Blood levels of a protein that helps regulate inflammation may also serve as a red flag for relapse in some schizophrenia patients, researchers said.

7 Aug 2012

Novartis’ pasireotide offers symptom relief for patients with advanced neuroendocrine tumors

A researcher at Moffitt Cancer Center and his international team of colleagues have reported study results on a novel multireceptor-targeted somatostatin analogue called pasireotide (SOM230) manufactured by Novartis Pharma AG.

7 Aug 2012

Adalimumab effective in maintaining remission in pediatric patients with Crohn's disease

Adalimumab (an anti-tumor necrosis factor [TNF] antibody) is effective in maintaining remission in certain pediatric patients with Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

7 Aug 2012

Exercise hope for drug-resistant hypertension

Even patients who have hypertension despite taking multiple antihypertensive drugs can achieve blood pressure reductions with a program of aerobic exercise, research shows.

6 Aug 2012

Vorinostat drives HIV from hiding

The addition of vorinostat to current antiretroviral therapy regimens can potentially help to eradicate hidden pockets of dormant human immunodeficiency virus, according to study results published in Nature.

6 Aug 2012

Pendrin a possible new target for diuretic therapy

In patients with fluid overload, inhibition of the chloride-absorbing transporter pendrin and the NaCl co-transporter may provide an effective diuretic regimen without triggering hypokalemia, research suggests.

6 Aug 2012

Boric acid treatment equals best practice for otitis media

Study findings show that a single application of boric acid powder followed by external auditory canal irrigation is as effective as topical ciprofloxacin eardrops for treating active chronic otitis media.

6 Aug 2012

‘Chicken Wing’ clue to stroke risk in atrial fibrillation

Patients with atrial fibrillation who have a Chicken Wing left atrial appendage morphology are less likely to have a stroke than those with other morphologies, research suggests.

6 Aug 2012

Wellcome Trust grants £1.6 million Translation Award for development of more effective radiotherapy

The Wellcome Trust has awarded a £1.6 million Translation Award to a research team led by the University of Lincoln to develop more effective radiotherapy treatment for thousands of cancer sufferers by providing unique monitoring and imaging for patients receiving proton therapy.

6 Aug 2012

CPRIT awards $48.2 million in new grants to investigators at UT Southwestern Medical Center

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded $48.2 million in new grants to investigators at UT Southwestern Medical Center to support cancer-related projects and to recruit pre-eminent cancer researchers.

6 Aug 2012

Biden seeks to allay veterans' concerns about benefits

Speaking at the Disabled American Veterans' national convention, Vice President Joe Biden reminded the group that veterans benefits were exempted from the automatic budget cuts that will be imposed on military and domestic programs as of Jan. 2. Meanwhile, President Barack Obama signed into law a legislative package that provides improved health care, housing, education and memorial services.

6 Aug 2012

Novel multireceptor-targeted somatostatin analogue found effective against neuroendocrine tumors

6 Aug 2012

New research center to expedite study of gene transfer approach

In an alliance aimed at bringing a new, personalized immunotherapy approach to patients with a wide variety of cancers, the University of Pennsylvania and Novartis announced today an exclusive global research and licensing agreement to further study and commercialize novel cellular immunotherapies using chimeric antigen receptor (CAR) technologies.

6 Aug 2012

NeoGenomics introduces new molecular assay that detects SF3B1 gene mutations

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today that it has validated and launched the first molecular assay for clinical use in the United States that detects mutations in the SF3B1 gene (splicing factor 3b, subunit 1).

6 Aug 2012

TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes

TWi Pharmaceuticals, Inc., a specialty pharmaceutical company based in Taiwan, today announced its fully owned subsidiary, TWi Biotechnology, Inc. has completed a multinational phase II dose-ranging study of AC-201, an orally available IL-1 Beta modulator, in 259 patients with type II diabetes uncontrolled on up to three oral medications.

6 Aug 2012

Clovis Oncology, Foundation Medicine enter diagnostic collaboration

Foundation Medicine, Inc. and Clovis Oncology, Inc. announced today that they have entered into a diagnostic collaboration.

6 Aug 2012

Scientists identify key factor that drives resistance to cancer drug

Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors - such as those of the breast, prostate, lung and colon - that have metastasized, or spread, throughout the body. A team of scientists led by Fred Hutchinson Cancer Research Center has discovered a key factor that drives this drug resistance - information that ultimately may be used to improve the effectiveness of therapy and buy precious time for patients with advanced cancer.

6 Aug 2012

Montefiore launches first fellowship program in Women's Physical Medicine and Rehabilitation

Montefiore Medical Center has launched the nation's first fellowship program in Women's Physical Medicine and Rehabilitation (WPM&R), and established a new clinical program in this specialty.

6 Aug 2012

Novartis, Penn partner to study and commercialize novel cellular immunotherapies for cancer

6 Aug 2012

Therapy News and Research

Scientists discover biological marker that may help identify patients’ response to antidepressants

Blood levels of IL-6 protein may also serve as red flag for relapse in schizophrenia patients

Novartis’ pasireotide offers symptom relief for patients with advanced neuroendocrine tumors

Adalimumab effective in maintaining remission in pediatric patients with Crohn's disease

Exercise hope for drug-resistant hypertension

Vorinostat drives HIV from hiding

Pendrin a possible new target for diuretic therapy

Boric acid treatment equals best practice for otitis media

‘Chicken Wing’ clue to stroke risk in atrial fibrillation

Wellcome Trust grants £1.6 million Translation Award for development of more effective radiotherapy

CPRIT awards $48.2 million in new grants to investigators at UT Southwestern Medical Center

Biden seeks to allay veterans' concerns about benefits

Novel multireceptor-targeted somatostatin analogue found effective against neuroendocrine tumors

New research center to expedite study of gene transfer approach

NeoGenomics introduces new molecular assay that detects SF3B1 gene mutations

TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes

Clovis Oncology, Foundation Medicine enter diagnostic collaboration

Scientists identify key factor that drives resistance to cancer drug

Montefiore launches first fellowship program in Women's Physical Medicine and Rehabilitation

Novartis, Penn partner to study and commercialize novel cellular immunotherapies for cancer

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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