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Investigational parathyroid hormone replacement effectively treats hypoparathyroidism

An investigational parathyroid hormone replacement effectively treated a rare disorder characterized by low calcium and high phosphate levels in the blood, a new study finds. The results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

New scoring system may better identify adolescents with metabolic syndrome

Researchers have developed a new scoring system that may better identify adolescents with the metabolic syndrome, a group at increased risk of later developing Type 2 diabetes and heart disease.

26 Jun 2012

Clinical trial to examine functional benefits of combined therapy against stroke

Researchers at Vanderbilt University Medical Center are leading an international clinical trial to examine the functional benefits of a combined therapy to treat acute ischemic stroke, a type of stroke where a blood clot becomes lodged in an artery within the brain, reducing blood flow and depriving brain cells of oxygen. Eighty-seven percent of strokes are ischemic.

26 Jun 2012

Vitamin D therapy may improve symptoms of depression in women

Women with moderate to severe depression had substantial improvement in their symptoms of depression after they received treatment for their vitamin D deficiency, a new study finds. The case report series will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Weight loss can reduce prevalence of low testosterone levels in men with prediabetes

Weight loss can reduce the prevalence of low testosterone levels in overweight, middle-aged men with prediabetes by almost 50 percent, a new study finds. Results will be presented Monday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Vatican official calls on international community to provide 'free, efficient' HIV treatment in Africa

Cardinal Tarcisio Bertone, the Vatican's secretary of state and number two official, "called Friday on the international community to provide 'free and efficient treatment' for AIDS in Africa, starting with pregnant women, mothers and their babies," Agence France-Presse reports.

26 Jun 2012

Combination of liraglutide and insulin controls blood sugar in obese adults with T1D

Obese adults with poorly controlled Type 1 diabetes can better control their blood sugar by adding liraglutide, a Type 2 diabetes drug, to their insulin therapy, a new study finds. The results, which will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston, also found that these diabetic patients lost weight and lowered their blood pressure.

26 Jun 2012

Targeted delivery of therapeutic gene can effectively treat Pompe disease

Gene therapy to replace the protein missing in Pompe disease can be effective if the patient's immune system does not react against the therapy. Targeted delivery of the gene to the liver, instead of throughout the body,suppresses the immune response, improving the therapeutic effect, according to an article published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.

26 Jun 2012

Long-term intensive combination lipid therapy may be effective against atherosclerotic disease

For the first time, a study has found that intensive cholesterol therapy involving a combination of drugs for 20 years may be more effective over the long run than taking a single statin medication.

26 Jun 2012

p53 protein may show a typical prion-like behavior when mutated

Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles. They are proteins in which the complex molecular three-dimensional folding process just went astray. For reasons not yet understood, the misfolding nature of prions is associated to their ability to sequester their normal counterparts and induce them to also adopt a misfolding conformation.

26 Jun 2012

Sitagliptin appears to reduce severity of reactive hypoglycemia

The diabetes drug sitagliptin appears to reduce the severity of reactive hypoglycemia, a form of low blood sugar that occurs after a meal, a preliminary study finds. The results will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

LLUMC suggests check list with six key attributes for successful proton therapy treatment

When a newly diagnosed cancer patient is considering treatment options, proton therapy might not be the first course that comes to mind. Yet over the past two decades proton therapy has continued to evolve as a viable alternative to chemotherapy and a less-invasive procedure than radiation or surgery, so much so that proton therapy is now considered the preferred course of treatment for many doctors and patients in the fight against cancer.

26 Jun 2012

Feinstein Institute to train clinicians on how to better care for patients with schizophrenia

The Zucker Hillside Hospital campus of the Feinstein Institute for Medical Research has been approved for a $9.3+ million federal grant to train clinicians on how to better care for patients with schizophrenia.

26 Jun 2012

Combination regimens trump monotherapy in fight against HIV transmission

A two- or three-drug combination is more effective at reducing intrapartum HIV acquisition than zidovudine monotherapy in babies who are at high risk for transmission, a study in The New England Journal of Medicine shows.

25 Jun 2012

HIV therapy affects bone mass within 2 years

Young men receiving antiretroviral therapy for recently diagnosed HIV are more likely to have low bone mineral density than are other men of a similar age, US researchers report.

25 Jun 2012

Enrollment commences in Stealth Peptides' Bendavia Phase II clinical study for acute STEMI

Stealth Peptides Incorporated, a privately held biopharmaceutical company developing innovative therapies for cardiovascular disease and its complications, announced today that the first patient was enrolled in its multinational Phase II clinical study with Bendavia focused on ischemia reperfusion and microvascular injuries for patients experiencing acute ST-segment elevation myocardial infarction.

25 Jun 2012

Afirma gene expression test can reduce unnecessary thyroid cancer surgeries

Veracyte, Inc., a molecular diagnostics company that is pioneering the emerging field of molecular cytology, today announced results from a large, prospective, multicenter study, which demonstrated the potential for the Afirma® Gene Expression Classifier, a gene expression test, to reduce the large number of unnecessary surgeries in thyroid cancer diagnosis by more than half.

25 Jun 2012

Deep brain stimulation reduces binge eating

Deep brain stimulation reduces binge eating in mice, suggesting that this surgery, which is approved for treatment of certain neurologic and psychiatric disorders, may also be an effective therapy for obesity. Presentation of the results will take place Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

25 Jun 2012

FDA approves Baxter's GAMMAGARD LIQUID for multifocal motor neuropathy

Baxter International Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved GAMMAGARD LIQUID 10% [Immune Globulin Infusion (Human)] as a treatment for multifocal motor neuropathy (MMN). This is the first immunoglobulin treatment approved for MMN patients in the United States, and it was approved for use with MMN patients in Europe in 2011.

From Baxter International Inc. 25 Jun 2012

MAP Pharmaceuticals completes End-of-Review meeting with FDA for LEVADEX NDA

MAP Pharmaceuticals, Inc. today announced that the Company completed an End-of-Review meeting with the United States Food and Drug Administration (FDA) for its New Drug Application (NDA) for LEVADEX (dihydroergotamine) inhalation aerosol.

25 Jun 2012

Therapy News and Research

Investigational parathyroid hormone replacement effectively treats hypoparathyroidism

New scoring system may better identify adolescents with metabolic syndrome

Clinical trial to examine functional benefits of combined therapy against stroke

Vitamin D therapy may improve symptoms of depression in women

Weight loss can reduce prevalence of low testosterone levels in men with prediabetes

Vatican official calls on international community to provide 'free, efficient' HIV treatment in Africa

Combination of liraglutide and insulin controls blood sugar in obese adults with T1D

Targeted delivery of therapeutic gene can effectively treat Pompe disease

Long-term intensive combination lipid therapy may be effective against atherosclerotic disease

p53 protein may show a typical prion-like behavior when mutated

Sitagliptin appears to reduce severity of reactive hypoglycemia

LLUMC suggests check list with six key attributes for successful proton therapy treatment

Feinstein Institute to train clinicians on how to better care for patients with schizophrenia

Combination regimens trump monotherapy in fight against HIV transmission

HIV therapy affects bone mass within 2 years

Enrollment commences in Stealth Peptides' Bendavia Phase II clinical study for acute STEMI

Afirma gene expression test can reduce unnecessary thyroid cancer surgeries

Deep brain stimulation reduces binge eating

FDA approves Baxter's GAMMAGARD LIQUID for multifocal motor neuropathy

MAP Pharmaceuticals completes End-of-Review meeting with FDA for LEVADEX NDA

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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