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New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

Penn study: New dental material kills bacteria and resists biofilm growth

Dentists rely on composite materials to perform restorative procedures, such as filling cavities. Yet these materials, like tooth enamel, can be vulnerable to the growth of plaque, the sticky biofilm that leads to tooth decay.

5 Dec 2017

Vanillin could prevent or reduce psoriatic skin inflammation

Small amounts of artificial vanilla extract, also known as vanillin, are in a wide range of products, from baked goods to perfumes.

29 Nov 2017

Researchers receive DoD grant to identify alternatives to opioids for pain management

What does a marine snail's ability to kill prey with two shots of venom have to do with the opioid epidemic ravaging the United States?

29 Nov 2017

Garlic compound can combat robust bacteria in patients with chronic infections

An active sulphurous compound found in garlic can be used to fight robust bacteria in patients with chronic infections, a new study from the University of Copenhagen indicates.

28 Nov 2017

TSRI chemists invent new method that simplifies late-stage modification of drug molecules

Chemists at The Scripps Research Institute have invented a technique that overcomes a long-standing problem in organic chemistry and should streamline the process of discovery and development for many new drugs.

27 Nov 2017

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases by inhibiting a protein instrumental in prompting the body to start attacking its own tissue.

21 Nov 2017

New research finds out how cinnamon may help fight against obesity

New research from the University of Michigan Life Sciences Institute has determined how a common holiday spice--cinnamon--might be enlisted in the fight against obesity.

21 Nov 2017

Preclinical study shows clear path toward effective treatment for rare bone disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute have led a preclinical study demonstrating that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE).

20 Nov 2017

Hibernating ground squirrels offer clues to fight against stroke-induced brain damage

In the fight against brain damage caused by stroke, researchers have turned to an unlikely source of inspiration: hibernating ground squirrels.

17 Nov 2017

Researchers identify new way to reduce risk of complications after joint surgery

Researchers identified a new way to lower the risk of complications after joint surgery, using a simple blood test. Patients with diabetes are more likely to need joint replacement surgery but also have a greater risk of serious complications after surgery, including heart attack, stroke, and wound infections, because of their underlying diabetes.

16 Nov 2017

New oxytocin chemical sensor could be first step towards early diagnosis of autism

Is it going to be possible to detect features of autism at birth? At the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw a sensor has come into being that means this may become a reality.

16 Nov 2017

Researchers test new vaccination strategy against HIV-related SIV in monkeys

According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year.

15 Nov 2017

UCR-led research discovers that human protein could be used to treat sepsis

A research team led by a biomedical scientist at the University of California, Riverside has discovered that the human protein resistin could be used to treat sepsis, the body's extreme and uncontrolled immune response to an infection.

14 Nov 2017

Social exclusion at preschool level leads to incidence of ADHD symptoms in young children

Children who experience social exclusion in preschool are at greater risk of becoming so-called "school losers". Norwegian researchers are studying what happens to children who are marginalized.

14 Nov 2017

New drug shows promise in mouse model of autism disorder

Scientists have performed a successful test of a possible new drug in a mouse model of an autism disorder. The candidate drug, called NitroSynapsin, largely corrected electrical, behavioral and brain abnormalities in the mice.

14 Nov 2017

Pilot study raises concerns about exposure of pregnant women to benzene in British Columbia

Université de Montréal research reveals that 29 pregnant women living near natural-gas hydraulic fracturing sites had a median concentration of a benzene biomarker in their urine that was 3.5 times higher than that found in women from the general Canadian population.

13 Nov 2017

New neurostimulator device will soon offer drug-free alternative for dry eye sufferers

A study of dry eye sufferers who inserted a handheld neurostimulator device in their nose to make their eyes produce more tears experienced significant relief from their disease, according to research presented today at AAO 2017, the 121st Annual Meeting of the American Academy of Ophthalmology.

13 Nov 2017

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Celgene Corporation recently announced results from two phase 3 trials evaluating the efficacy and safety of the drug ozanimod.

10 Nov 2017

Compound News and Research

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

Penn study: New dental material kills bacteria and resists biofilm growth

Vanillin could prevent or reduce psoriatic skin inflammation

Researchers receive DoD grant to identify alternatives to opioids for pain management

Garlic compound can combat robust bacteria in patients with chronic infections

TSRI chemists invent new method that simplifies late-stage modification of drug molecules

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

New research finds out how cinnamon may help fight against obesity

Preclinical study shows clear path toward effective treatment for rare bone disease

Hibernating ground squirrels offer clues to fight against stroke-induced brain damage

Researchers identify new way to reduce risk of complications after joint surgery

New oxytocin chemical sensor could be first step towards early diagnosis of autism

Researchers test new vaccination strategy against HIV-related SIV in monkeys

UCR-led research discovers that human protein could be used to treat sepsis

Social exclusion at preschool level leads to incidence of ADHD symptoms in young children

New drug shows promise in mouse model of autism disorder

Pilot study raises concerns about exposure of pregnant women to benzene in British Columbia

New neurostimulator device will soon offer drug-free alternative for dry eye sufferers

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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