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PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

Study shows how two proteins provide a tunnel for bad cholesterol to enter the cells

A study has outlined how two proteins are instrumental to bringing cholesterol into cells – a finding that has implications for a range of diseases.

26 Jun 2020

Study shows why ApoE4 increases risk of Alzheimer's disease

Apolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients, including with polyunsaturated fatty acids - which are building blocks of the membranes surrounding the neurons.

26 Jun 2020

New study explores post-COVID-19 inflammatory condition in children

In recent weeks, a multisystem hyperinflammatory condition has emerged in children in association with prior exposure or infection to SARS-CoV-2.

25 Jun 2020

Scientists pinpoint mutations that increase bacterial deadliness

As far as humans are concerned, bacteria can be classified as either harmful, pathogenic bacteria and harmless or beneficial non-pathogenic bacteria.

25 Jun 2020

Study assesses impact of anti-SARS-CoV-2 convalescent plasma in COVID-19 disease

The current COVID-19 pandemic is still very much active in most parts of the world. In the absence of effective antiviral drugs or vaccines, scientists are studying the use of blood plasma from convalescent COVID-19 patients, banking on its neutralizing antibody content.

25 Jun 2020

Immune response variations across the COVID-19 spectrum

A new study published on the preprint server medRxiv in June 2020 describes differences in the adaptive and innate immune response in mild, moderate, and severe COVID-19. This may mean that permanent immune responses occur only in patients who recover from severe COVID-19.

25 Jun 2020

Platelets may be contributing to COVID-19

The current pandemic of COVID-19 is characterized mainly by severe acute respiratory distress of the lungs, but other organ dysfunctions are also being observed, including the heart and blood vessels. Now, a new paper published on the preprint server medRxiv* in June 2020 describes the abnormal activation of platelets in this disease and the link between this phenomenon and poor outcomes for COVID-19 patients.

24 Jun 2020

Study finds entry point for curbing the evolution of antibiotic resistance

The team of Professor Tobias Bollenbach from the Institute for Biological Physics at the University of Cologne has published a study on a new approach to improving the effectiveness of antibiotics in bacterial infections.

24 Jun 2020

Cell signaling pathway may offer new drugs for tuberous sclerosis complex

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

24 Jun 2020

Researchers develop a noninvasive technology to destroy cancer cells

An international research team led by Dr. Tali Ilovitsh of the Biomedical Engineering Department at Tel Aviv University developed a noninvasive technology platform for gene delivery into breast cancer cells.

24 Jun 2020

Study ratifies the main symptoms of COVID-19

A persistent cough and fever have been confirmed as the most prevalent symptoms associated with COVID-19, according to a major review of the scientific literature.

24 Jun 2020

Tomocube holotomography microscopy reveals novel cholesterol membrane transport system in erythrocytes infected with fatal malaria parasite

The first study to elucidate the dynamics of membrane cholesterol transport in erythrocytes has been successfully concluded using holotomography microscopy.

From Tomocube Inc. 24 Jun 2020

Abnormal findings in testicular tissue of COVID-19 patients, SARS-CoV-2 mostly undetected

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 9.263 million cases and taken more than 477,000 lives as of June 24, 2020 – just six months after the initial outbreak in Wuhan, China, was reported. The illness, called COVID-19 disease, caused by SARS-CoV-2 is a severe pneumonic illness, caused by the entry of the virus into the type II alveolar cells.

24 Jun 2020

Scientists create hollow, spherical sacks using protein and RNA

Using protein and RNA, scientists have created hollow, spherical sacks known as vesicles.

23 Jun 2020

Prevention of sugar uptake can make cancer cells more sensitive to chemotherapy

By preventing sugar uptake, researchers succeeded in increasing the cancer cells' sensitivity to chemotherapeutic treatment.

23 Jun 2020

SARS-CoV-2 induces broad T cell response in recovering patients

A new study published on the preprint server bioRxiv in June 2020 shows that T cell responses in COVID-19 patients are broader and more robust in severe disease and are explicitly directed against spike, memory, and ORF3a proteins.

23 Jun 2020

Researchers develop method to assess mitochondrial respiration in frozen tissues

Scientists led by Dr. Orian Shirihai, director of the metabolism theme at the David Geffen School of Medicine at UCLA, have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples, even years after they have been collected.

23 Jun 2020

Scientists create 'all-atom' model of SARS-CoV-2 spike protein

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease (COVID-19), an illness that has spread across the globe, infecting more than 9 million people. The novel coronavirus invades cells through "spike proteins," which sticks and binds itself to a host cell.

23 Jun 2020

Single-dose Israeli vaccine candidate protective against SARS-CoV-2

Now, a new Israeli study published on the preprint server bioRxiv in June 2020 reports a new recombinant vaccine expressing the S or spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be highly protective with a single dose in an animal model. This could be a gamechanger in the fight to contain the outbreak.

23 Jun 2020