Proliferation News and Research

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Oxygen-rich postnatal atmosphere results in cell cycle arrest of cardiomyocytes

Scientific research at UT Southwestern Medical Center previously discovered that the newborn animal heart can heal itself completely, whereas the adult heart lacks this ability. New research by the same team today has revealed why the heart loses its incredible regenerative capability in adulthood, and the answer is quite simple - oxygen.

25 Apr 2014

Exposure to environmental enrichment can induce neurogenesis of hippocampal region

Many studies have shown that exposure to environmental enrichment can induce neurogenesis of the hippocampal region, thus improving learning and memory.

23 Apr 2014

Scientists examine Gpr109a receptor to find potential treatment for diabetic retinopathy

Like a daily pill to lower cholesterol can reduce heart attack and stroke risk, an easy-to-use agent that reduces eye inflammation could help save the vision of diabetics, scientists say.

22 Apr 2014

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death.

22 Apr 2014

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine.

21 Apr 2014

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven't been able to explain why. Now, a team of Dana-Farber Cancer Institute investigators has uncovered a connection between the two conditions.

21 Apr 2014

Brain-related discovery could revolutionize treatment for attention-deficit disorders

Two Simon Fraser University psychologists have made a brain-related discovery that could revolutionize doctors' perception and treatment of attention-deficit disorders.

19 Apr 2014

Special supplement explores the causes of distracted driving among teens

Motor vehicle crashes rank as the leading cause of teen deaths and in 2008, 16% of all distraction-related fatal automobile crashes involved drivers under 20 years of age.

17 Apr 2014

Professor from INRS receives NIH grant to explore biomedical potential in field of oncology

Professor Nicolas Doucet of the Centre INRS-Institut Armand-Frappier has just received a research grant from the National Institutes of Health (NIH) in the amount of nearly US$600,000. The 5-year grant is to pursue cutting-edge research in the workings of tiny proteins called RNases and to explore their biomedical potential in the field of oncology as well as in inflammation and asthma.

17 Apr 2014

New study identifies potential target for colorectal cancer treatment

A new study identifies a molecule that is a probable driving force in colorectal cancer and suggests that the molecule could be an important target for colorectal cancer treatment and a valuable biomarker of tumor progression.

15 Apr 2014

Study: Honokiol reduces proliferation of renal cell carcinoma

A new study shows that honokiol, a small molecule polyphenol extract derived from Magnolia officinalis bark, reduces proliferation of renal cell carcinoma.

9 Apr 2014

Researchers identify experimental drugs to block treatment-resistant leukemia

Research in mice and human cell lines has identified an experimental compound dubbed TTT-3002 as potentially one of the most potent drugs available to block genetic mutations in cancer cells blamed for some forms of treatment-resistant leukemia.

9 Apr 2014

Abnormal levels of lipid molecules can trigger autism during prenatal brain development

In a groundbreaking York University study, researchers have found that abnormal levels of lipid molecules in the brain can affect the interaction between two key neural pathways in early prenatal brain development, which can trigger autism.

9 Apr 2014

PeptiDream develops novel macrocyclic peptide inhibitor for treatment of multiple influenza strains

PeptiDream Inc., a public Tokyo-based biopharmaceutical company ("PeptiDream")( TOKYO:4587) announced today, in collaboration with The Tokyo Metropolitan Institute of Medical Science ("Tokyo Metropolitan Institute") the discovery and development of a novel macrocyclic peptide inhibitor for the treatment of multiple influenza strains.

8 Apr 2014

Combination therapy with MEK and BRAF inhibitors for anaplastic thyroid cancer proves effective

Researchers from the Jacks Laboratory at MIT's Koch Institute for Integrative Cancer Research (KI) have developed and characterized a genetically engineered mouse that successfully models progression from papillary thyroid cancer, which has an excellent prognosis, to anaplastic thyroid cancer (ATC), a highly lethal disease.

8 Apr 2014

NRAS gene that plays fundamental role in cancer development produces five gene variants, says study

A new study shows that a gene discovered 30 years ago and now known to play a fundamental role in cancer development produces five different gene variants (called isoforms), rather than just the one original form, as thought.

8 Apr 2014

Compounds from plant confer protective effects against breast cancer, say researchers

Compounds derived from plant-based sources - including garlic, broccoli and medicine plants - confer protective effects against breast cancer, explain researchers at the University of Pittsburgh Cancer Institute (UPCI), partner with the UPMC CancerCenter.

7 Apr 2014

Deciphera Pharmaceuticals initiates Phase 1 clinical trial of pan-RAF inhibitor LY3009120

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7 Apr 2014

Too little or too much of SRPK1 enzyme promotes cancer, shows research

Researchers at the University of California, San Diego School of Medicine have found that too little or too much of an enzyme called SRPK1 promotes cancer by disrupting a regulatory event critical for many fundamental cellular processes, including proliferation.

4 Apr 2014

Interrupting diurnal rhythms impairs healing immediately after heart attack, study shows

To improve recovery for heart attack patients, hospitals should maintain normal day and night cycles for those patients during the first few days after the attack, say University of Guelph researchers.

2 Apr 2014

Proliferation News and Research

Oxygen-rich postnatal atmosphere results in cell cycle arrest of cardiomyocytes

Exposure to environmental enrichment can induce neurogenesis of hippocampal region

Scientists examine Gpr109a receptor to find potential treatment for diabetic retinopathy

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Brain-related discovery could revolutionize treatment for attention-deficit disorders

Special supplement explores the causes of distracted driving among teens

Professor from INRS receives NIH grant to explore biomedical potential in field of oncology

New study identifies potential target for colorectal cancer treatment

Study: Honokiol reduces proliferation of renal cell carcinoma

Researchers identify experimental drugs to block treatment-resistant leukemia

Abnormal levels of lipid molecules can trigger autism during prenatal brain development

PeptiDream develops novel macrocyclic peptide inhibitor for treatment of multiple influenza strains

Combination therapy with MEK and BRAF inhibitors for anaplastic thyroid cancer proves effective

NRAS gene that plays fundamental role in cancer development produces five gene variants, says study

Compounds from plant confer protective effects against breast cancer, say researchers

Deciphera Pharmaceuticals initiates Phase 1 clinical trial of pan-RAF inhibitor LY3009120

Too little or too much of SRPK1 enzyme promotes cancer, shows research

Interrupting diurnal rhythms impairs healing immediately after heart attack, study shows

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