Therapy News and Research

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More reason to restrict hormone therapy during menopause

Researchers have found further evidence to show that menopausal hormone therapy increases the risk for high blood pressure in postmenopausal women.

13 Jul 2012

Adding functional skills training to CRT improves schizophrenia functioning

Adding functional skills training to cognitive remediation therapy significantly improves functional competence and real-world behavior in patients with schizophrenia, show study findings.

13 Jul 2012

Incident HF an ‘extreme high-risk’ condition

Patients have a markedly increased risk for stroke and death in the month following a new heart failure diagnosis, say researchers.

13 Jul 2012

Scientists isolate new type of energy-burning fat cell

Scientists at Dana-Farber Cancer Institute have isolated a new type of energy-burning fat cell in adult humans which they say may have therapeutic potential for treating obesity.

13 Jul 2012

OncoMed commences dosing in OMP-54F28 Phase I clinical trial for advanced solid tumor cancers

OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer stem cells, or tumor-initiating cells, today announced that patient dosing has begun in a Phase I clinical trial of OMP-54F28 in patients with advanced solid tumor cancers.

13 Jul 2012

Discovery sheds light on why human body is unable to fight off HIV infection

University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection.

13 Jul 2012

Cubist initiates CB-315 Phase 3 trial for Clostridium difficile-associated diarrhea

Cubist Pharmaceuticals, Inc. today announced the initiation of its pivotal Phase 3 studies evaluating the efficacy and safety of CB-315 in patients with Clostridium difficile-associated diarrhea, or CDAD, with enrollment of a patient in the first of two planned identical global trials.

13 Jul 2012

Heart disease risk in elderly could be lowered by drugs

More patients aged 75 and over should be prescribed drugs to help lower their risk of cardiovascular disease, a study published today on bmj.com suggests.

13 Jul 2012

Early surgery best for infective endocarditis

Compared with conventional treatment, early surgery for patients with infective endocarditis and large vegetations significantly reduces the risk for death or embolic events by reducing the risk for systemic embolism, show results from a randomized trial.

12 Jul 2012

Opioids for chronic noncancer pain discouraged

US experts have called for more selective and cautious opioid prescribing for chronic noncancer pain, because of concerns over misuse of the drugs and continued uncertainty over when and for how long they should be prescribed.

12 Jul 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

Mayo Clinic, 18 other leading research institutions urge Congress to maintain funding levels for NIH

Mayo Clinic and 18 other leading medical research institutions nationwide are urging congressional leaders to maintain current funding levels for the National Institutes of Health.

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

Nonsurgical treatment may be more beneficial for baseball players with SLAP tears

Surgically repairing a painful shoulder injury in baseball players known as a SLAP tear (superior labral) varies widely and often doesn't allow for return to play at the same level as before the injury. However, researchers presenting their findings at the American Orthopaedic Society for Sports Medicine's Annual Meeting in Baltimore, Maryland suggest that nonsurgical treatment may be more beneficial.

12 Jul 2012

Low-fat, high fruit and vegetable diet may help reduce menopausal symptoms

Weight loss that occurs in conjunction with a low-fat, high fruit and vegetable diet may help to reduce or eliminate hot flashes and night sweats associated with menopause, according to a Kaiser Permanente Division of Research study that appears in the current issue of Menopause.

12 Jul 2012

Eschar-derived cells may be used for tissue engineering

A research team in the Netherlands has found that cells from burn eschar, the non-viable tissue remaining after burn injury and normally removed to prevent infection, can be a source of mesenchymal cells that may be used for tissue engineering.

12 Jul 2012

Physiologists, neuropathologists identify origin of cancer metastasis formation

It is not primary tumors that are responsible for the majority of cancer deaths, but rather their metastases. Physiologists and neuropathologists from the University of Zurich have now identified the origin of metastasis formation, thereby becoming the first to reveal the pathway of metastasizing intestinal cancer cells out of the blood stream. The results allow new approaches in the development of cancer therapies.

12 Jul 2012

Mindfulness techniques show health benefits

Specific types of "mindfulness practices" including Zen meditation have research-proven benefits for patients with certain physical and mental health problems, according to a report in the July Journal of Psychiatric Practice.

12 Jul 2012

Study details how resistance to targeted drug therapy emerges in colorectal cancers

A Harvard researcher studying the evolution of drug resistance in cancer is predicting that, in a few decades, "many, many cancers could be manageable."

12 Jul 2012

Therapy News and Research

More reason to restrict hormone therapy during menopause

Adding functional skills training to CRT improves schizophrenia functioning

Incident HF an ‘extreme high-risk’ condition

Scientists isolate new type of energy-burning fat cell

OncoMed commences dosing in OMP-54F28 Phase I clinical trial for advanced solid tumor cancers

Discovery sheds light on why human body is unable to fight off HIV infection

Cubist initiates CB-315 Phase 3 trial for Clostridium difficile-associated diarrhea

Heart disease risk in elderly could be lowered by drugs

Early surgery best for infective endocarditis

Opioids for chronic noncancer pain discouraged

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

Mayo Clinic, 18 other leading research institutions urge Congress to maintain funding levels for NIH

Communication between brain and muscle cells is short-lived without LRP4 protein

Nonsurgical treatment may be more beneficial for baseball players with SLAP tears

Low-fat, high fruit and vegetable diet may help reduce menopausal symptoms

Eschar-derived cells may be used for tissue engineering

Physiologists, neuropathologists identify origin of cancer metastasis formation

Mindfulness techniques show health benefits

Study details how resistance to targeted drug therapy emerges in colorectal cancers

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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