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Study details how Parkinson's disease spreads through the brain

Van Andel Institute announces that researchers at Lund University in Sweden have published a study detailing how Parkinson's disease spreads through the brain. Experiments in rat models uncover a process previously used to explain mad cow disease, in which misfolded proteins travel from sick to healthy cells.

27 Jun 2012

First clinical trial to test cardiac drug regimen for DMD

The first landmark randomized clinical trial for a cardiac drug regimen in Duchenne muscular dystrophy (DMD) is testing whether earlier treatment can stop or slow down heart damage that usually kills people with the disease.

27 Jun 2012

Caltech researchers develop technique to focus light inside biological tissue

Imagine if doctors could perform surgery without ever having to cut through your skin. Or if they could diagnose cancer by seeing tumors inside the body with a procedure that is as simple as an ultrasound.

27 Jun 2012

HemoGenix receives first Master File Number from FDA CBER for HALO-96 PQR

HemoGenix announced today that FDA CBER has given HemoGenix its first Master File Number for an in vitro blood stem cell potency, quality and release assay (HALO-96 PQR) for cellular therapy products used for stem cell transplantation purposes. HALO-96 PQR is the first commercially available stem cell potency assay for cellular therapy products.

27 Jun 2012

Poor prognosis for heart transplant patients with restenosis

Orthotopic heart transplant patients who develop in-stent restenosis after percutaneous coronary intervention have a poor long-term prognosis, research suggests.

26 Jun 2012

Marker to identify patients who have difficulties in maintaining body weight

A pre-diet measurement of two hormones related to weight regulation can help predict which dieters will be more likely to maintain their weight loss and who will not, according to a new study. The results will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Degludec reduces risk of nighttime low blood sugar in elderly diabetic adults

A new variety of long-lasting insulin, called insulin degludec, lowers the risk of nighttime low blood sugar in elderly diabetic adults compared with insulin glargine, a systematic review of diabetes studies has found.

26 Jun 2012

LOGIC-Insulin software more effectively controls blood-sugar levels among critically ill patients

A computer-software program more effectively controlled blood-sugar levels among critically ill patients than nurse-directed care did, according to the first large clinical trial of its kind. The results will be presented at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Investigational parathyroid hormone replacement effectively treats hypoparathyroidism

An investigational parathyroid hormone replacement effectively treated a rare disorder characterized by low calcium and high phosphate levels in the blood, a new study finds. The results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

New scoring system may better identify adolescents with metabolic syndrome

Researchers have developed a new scoring system that may better identify adolescents with the metabolic syndrome, a group at increased risk of later developing Type 2 diabetes and heart disease.

26 Jun 2012

Clinical trial to examine functional benefits of combined therapy against stroke

Researchers at Vanderbilt University Medical Center are leading an international clinical trial to examine the functional benefits of a combined therapy to treat acute ischemic stroke, a type of stroke where a blood clot becomes lodged in an artery within the brain, reducing blood flow and depriving brain cells of oxygen. Eighty-seven percent of strokes are ischemic.

26 Jun 2012

Vitamin D therapy may improve symptoms of depression in women

Women with moderate to severe depression had substantial improvement in their symptoms of depression after they received treatment for their vitamin D deficiency, a new study finds. The case report series will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Weight loss can reduce prevalence of low testosterone levels in men with prediabetes

Weight loss can reduce the prevalence of low testosterone levels in overweight, middle-aged men with prediabetes by almost 50 percent, a new study finds. Results will be presented Monday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Vatican official calls on international community to provide 'free, efficient' HIV treatment in Africa

Cardinal Tarcisio Bertone, the Vatican's secretary of state and number two official, "called Friday on the international community to provide 'free and efficient treatment' for AIDS in Africa, starting with pregnant women, mothers and their babies," Agence France-Presse reports.

26 Jun 2012

Combination of liraglutide and insulin controls blood sugar in obese adults with T1D

Obese adults with poorly controlled Type 1 diabetes can better control their blood sugar by adding liraglutide, a Type 2 diabetes drug, to their insulin therapy, a new study finds. The results, which will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston, also found that these diabetic patients lost weight and lowered their blood pressure.

26 Jun 2012

Targeted delivery of therapeutic gene can effectively treat Pompe disease

Gene therapy to replace the protein missing in Pompe disease can be effective if the patient's immune system does not react against the therapy. Targeted delivery of the gene to the liver, instead of throughout the body,suppresses the immune response, improving the therapeutic effect, according to an article published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.

26 Jun 2012

Long-term intensive combination lipid therapy may be effective against atherosclerotic disease

For the first time, a study has found that intensive cholesterol therapy involving a combination of drugs for 20 years may be more effective over the long run than taking a single statin medication.

26 Jun 2012

p53 protein may show a typical prion-like behavior when mutated

Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles. They are proteins in which the complex molecular three-dimensional folding process just went astray. For reasons not yet understood, the misfolding nature of prions is associated to their ability to sequester their normal counterparts and induce them to also adopt a misfolding conformation.

26 Jun 2012

Sitagliptin appears to reduce severity of reactive hypoglycemia

The diabetes drug sitagliptin appears to reduce the severity of reactive hypoglycemia, a form of low blood sugar that occurs after a meal, a preliminary study finds. The results will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

LLUMC suggests check list with six key attributes for successful proton therapy treatment

When a newly diagnosed cancer patient is considering treatment options, proton therapy might not be the first course that comes to mind. Yet over the past two decades proton therapy has continued to evolve as a viable alternative to chemotherapy and a less-invasive procedure than radiation or surgery, so much so that proton therapy is now considered the preferred course of treatment for many doctors and patients in the fight against cancer.

26 Jun 2012

Therapy News and Research

Study details how Parkinson's disease spreads through the brain

First clinical trial to test cardiac drug regimen for DMD

Caltech researchers develop technique to focus light inside biological tissue

HemoGenix receives first Master File Number from FDA CBER for HALO-96 PQR

Poor prognosis for heart transplant patients with restenosis

Marker to identify patients who have difficulties in maintaining body weight

Degludec reduces risk of nighttime low blood sugar in elderly diabetic adults

LOGIC-Insulin software more effectively controls blood-sugar levels among critically ill patients

Investigational parathyroid hormone replacement effectively treats hypoparathyroidism

New scoring system may better identify adolescents with metabolic syndrome

Clinical trial to examine functional benefits of combined therapy against stroke

Vitamin D therapy may improve symptoms of depression in women

Weight loss can reduce prevalence of low testosterone levels in men with prediabetes

Vatican official calls on international community to provide 'free, efficient' HIV treatment in Africa

Combination of liraglutide and insulin controls blood sugar in obese adults with T1D

Targeted delivery of therapeutic gene can effectively treat Pompe disease

Long-term intensive combination lipid therapy may be effective against atherosclerotic disease

p53 protein may show a typical prion-like behavior when mutated

Sitagliptin appears to reduce severity of reactive hypoglycemia

LLUMC suggests check list with six key attributes for successful proton therapy treatment

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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