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Penn Medicine study maps brain circuits impacted by psilocybin

Researchers at Penn Medicine have identified specific brain circuits that are impacted by psilocybin-the active compound found in some psychedelic mushrooms-which could lead to new paths forward for pain and mental health management options.

2 Oct 2025

Scientists directly visualize protein clusters linked to Parkinson’s for the first time

Scientists have, for the first time, directly visualized and quantified the protein clusters believed to trigger Parkinson's, marking a major advance in the study of the world's fastest-growing neurological disease.

2 Oct 2025

Engineered CAR T cells show promise against solid tumors

Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers.

2 Oct 2025

Second round of exercise boosts muscle growth in mice

New research offers potential good news for those who've lapsed at the gym. The study found that mice that voluntarily ran on an exercise wheel for four weeks, stopped for four weeks and ran again for another four weeks saw unexpected gains.

2 Oct 2025

New molecular sensor for taste-based detection of influenza

Flu season is fast approaching in the northern hemisphere. And a taste-based influenza test could someday have you swapping nasal swabs for chewing gum.

2 Oct 2025

New insights into how antimicrobial peptides kill bacterial cells

New research into antimicrobial peptides, small chains of amino acids able to damage bacterial cells, shows why some peptides are more effective at doing that and also why some cells are more vulnerable.

2 Oct 2025

McGill researchers create AI tool to detect hidden disease markers in single cells

McGill University researchers have developed an artificial intelligence tool that can detect previously invisible disease markers inside single cells.

2 Oct 2025

NIH funds multi-state pilot for genome sequencing in newborn screening

Mass General Brigham and Ariadne Labs, alongside Boston Children's Hospital, Albert Einstein College of Medicine, the Association of Public Health Laboratories (APHL), Case Western Reserve University, Baylor College of Medicine, and sequencing partners GeneDx and Illumina, today announced the launch of BEACONS (Building Evidence and Collaboration for GenOmics in Nationwide Newborn Screening), the nation's first multi-state genomic newborn screening initiative.

2 Oct 2025

Prediabetes can go into remission without weight loss

Research shows up to 22% of prediabetic individuals achieve remission without weight loss, emphasizing metabolic health over weight loss in diabetes prevention.

2 Oct 2025

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

Discover how Bruker and the University of Manchester joined forces to discover more on the dynamics of complex protein.

From Bruker BioSpin Group 2 Oct 2025

Ozone exposure weakens lung function and reshapes the oral microbiome

Ozone exposure reshapes the oral microbiome and reduces lung function, particularly in men, revealing significant health risks associated with pollution.

1 Oct 2025

Boosting the immune system to prevent cancer recurrence and improve survival

In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children's Hospital report new evidence that a novel means of boosting the natural immune system prevents cancer recurrence and improves survival.

30 Sep 2025

New 'GLed' tool enables real-time monitoring of T cell activity

The new 'GLed' tool, unique in its reversibility, allows the functional state of T cells to be observed for the first time, representing a crucial advance in personalizing treatments in immunotherapy, transplants, and autoimmune diseases.

30 Sep 2025

Study shows prediabetes remission does not always require weight loss

Remission of prediabetes can occur even without weight loss, protecting against type 2 diabetes in up to 22% of individuals. Metabolic improvements, healthier fat distribution, and enhanced β-cell function, not body weight change, drive this benefit.

30 Sep 2025

New data analysis method accelerates design of safer covalent inhibitors

Researchers at Baylor College of Medicine have developed a powerful new data analysis method named COOKIE-Pro (Covalent Occupancy Kinetic Enrichment via Proteomics) that provides a comprehensive, unbiased view of how a class of drugs, called covalent inhibitors, interacts with proteins throughout the cell.

30 Sep 2025

Khat use linked to autoimmune hepatitis in young men

Khat (Catha edulis), a plant chewed for its stimulant effects by millions in East Africa and the Arabian Peninsula, is increasingly recognized for its hepatotoxic potential.

30 Sep 2025

Inflammation at the heart’s core: What clinicians and families can do now

Chronic low-grade inflammation is a key driver of cardiovascular disease, even when cholesterol is controlled. The ACC’s 2025 Scientific Statement highlights hsCRP as a routine risk marker and outlines lifestyle and pharmacologic anti-inflammatory strategies for prevention and treatment.

30 Sep 2025

Randomized trial shows exercise benefits for post-COVID immune regulation

Exercise can help to restore a more normal, well-regulated immune system in people with post-COVID syndrome, according to a gold-standard randomised-controlled trial presented at the European Respiratory Society Congress in Amsterdam, the Netherlands.

30 Sep 2025

Stereotactic radiotherapy offers long-term survival outcomes comparable to surgery for NSCLC patients

A new clinical trial report finds that stereotactic radiation therapy offers long-term survival outcomes comparable to surgery for patients with small, early-stage non-small cell lung cancer (NSCLC). Patients in the study who received radiation also reported fewer side effects after treatment.

30 Sep 2025

New immune system assessment tool could help guide critical care treatment

When a patient enters the emergency department in critical condition, doctors must quickly run through a crucial list of questions: Does the patient have an infection? If so, is it bacterial or viral? Do they require treatment? Can the patient recover at home safely or do they need to be hospitalized?

30 Sep 2025