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Novel drug shows promise in mouse models of human metastatic breast cancer

A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character - from aggressive to static, and no longer shedding cells that can colonize distant organs of the body. Indeed, most patients with breast and other forms of cancer who succumb to the illness do so because of the cancer's unstoppable spread.

23 Dec 2015

ChemicalInfo partners with e-samples to accelerate sample ordering process for CIS Subscribers

ChemicalInfo, providers of the most comprehensive online databases for chemical and pharmaceutical companies and those who do business with them, announces partnership with e-samples, a comprehensive database offering integrated solutions for samples and development product supply chain processes.

17 Dec 2015

Drug use remains stable among teens, MTF survey shows

The 2015 Monitoring the Future survey (MTF) shows decreasing use of a number of substances, including cigarettes, alcohol, prescription opioid pain relievers, and synthetic cannabinoids ("synthetic marijuana"). Other drug use remains stable, including marijuana, with continued high rates of daily use reported among 12th graders, and ongoing declines in perception of its harms.

17 Dec 2015

Honeywell acquires Sigma-Aldrich's laboratory research chemicals business

Honeywell today announced that it has completed the acquisition of the Seelze, Germany-based laboratory research chemicals business from Sigma-Aldrich, broadening Honeywell's offerings for high-purity solutions for drug discovery, medical diagnostic testing and other laboratory applications.

15 Dec 2015

Antibiotic resistance may help find drugs to combat amyloid formation

Amyloid diseases such as Parkinson's, Alzheimer's and type-2 diabetes pose a particular problem for drug designers because they do not present a clear target structure to aim at.

15 Dec 2015

Kaiser Permanente bans 'germ-fighting' antimicrobial agents for use in hospitals

Concerned about mounting exposure to toxic chemicals in everyday life and the threat of drug-resistant bacteria, Kaiser Permanente has banned paint and other interior building products treated with "germ-fighting" antimicrobial agents for use in its hospitals and other buildings.

13 Dec 2015

CPSC announces grant awards to prevent pool and spa drownings, drain entrapments

U.S. Consumer Product Safety Commission Chairman Elliot F. Kaye and U.S. Rep. Debbie Wasserman Schultz (FL-23) announced today the awardees of a first-of-its-kind grant program aimed at preventing pool and spa drownings and drain entrapments. Five local governments will receive more than $780,000 in Pool Safely Grant Program (PSGP) funds.

12 Dec 2015

New research sheds light on outcomes for patients with thyroid cancer

Thyroid cancer survivors report poor quality of life after diagnosis and treatment compared with other patients who are diagnosed with more lethal cancers, according to new research from the University of Chicago Medicine.

12 Dec 2015

UC San Diego biologists develop a method to screen natural products for new antibiotics

Biologists at UC San Diego have found that a method they developed to identify and characterize new antibiotics can be employed to screen natural products quickly for compounds capable of controlling antibiotic resistant bacteria.

11 Dec 2015

Early life exposures to toxic chemicals reduce infants' response to TB vaccine

Early life exposures to toxic chemicals such as PCBs and DDT dampen an infant's response to the tuberculosis vaccine, according to a new study from the University of Rochester Environmental Health Sciences Center.

11 Dec 2015

DZNE molecular biologist to receive Gottfried Wilhelm Leibniz Prize for research on neurons

The molecular biologist Frank Bradke (46), group leader at the German Center for Neurodegenerative Diseases (DZNE) and professor for neurobiology at the University of Bonn, will be awarded the "Gottfried Wilhelm Leibniz Prize", which is endowed with 2.5 million euros.

11 Dec 2015

Endocrine-disrupting chemicals pose threat to male reproductive health

The birth rate is declining in all industrialised countries, and socioeconomic factors and women's age are not solely to blame. Male reproductive health and environmental factors are also significant, as concluded in a new scientific review article.

11 Dec 2015

Vagus nerve stimulation prevents hemorrhagic complications following surgery

Stimulating the vagus nerve is a potentially efficacious and safe way to stop the flow of blood and prevent hemorrhagic complications following surgery and other invasive procedures, according to a researcher in the Center for Bioelectronic Medicine at The Feinstein Institute for Medical Research.

11 Dec 2015

Neuroscientists find link between neurotransmitter GABA and tactile learning

In an international collaboration with the Johns Hopkins University (Baltimore, MD, USA), neuroscientists at the Ruhr-University Bochum have determined a link between brain levels of the neurotransmitter GABA, the main source of inhibition in the brain, and tactile learning. Using magnetic resonance spectroscopy, they were able to show that success in learning can be predicted by baseline GABA levels.

11 Dec 2015

Environmental and lifestyle factors damage men's reproductive health

Environmental and lifestyle factors are damaging men's reproductive health and may be playing a large role in decreasing fertility rates in industrialized countries, a new study in Physiological Reviews reports. Socioeconomic influences and female reproductive health cannot solely be blamed for higher incidences of infertility, the study supports.

10 Dec 2015

TET proteins needed to maintain genome instability, say researchers

Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers at the La Jolla Institute for Allergy and Immunology demonstrate that TET proteins collectively constitute a major class of tumor suppressors and are required to maintain genome instability.

9 Dec 2015