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Augmentation therapy can save lives of people with alpha-1 antitrypsin deficiency, study shows

Boosting levels of a deficient protein has clear survival benefits for people with the genetic condition alpha-1 antitrypsin deficiency (AATD), according to new research led by RCSI University of Medicine and Health Sciences.

1 Nov 2023

JAK inhibitors offer effective and convenient treatment option for arthritis patients

According to a new paper in Rheumatology, published by Oxford University Press, JAK inhibitors, which doctors have used to treat patients with arthritis despite concerns about the effectiveness of such drugs, actually do work quite well.

1 Nov 2023

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Researchers aimed to identify dependable protein biomarkers for multiple sclerosis (MS).

1 Nov 2023

Researchers harness a combination of lab-grown cells to regenerate damaged heart muscle

Researchers at the University of Wisconsin–Madison and Academia Sinica of Taiwan have harnessed a combination of lab-grown cells to regenerate damaged heart muscle.

31 Oct 2023

AI may help identify potential gonorrhea vaccine proteins

Gonorrhea, a sexually transmitted bacterial infection that affects more than 80 million people worldwide every year, has become resistant to almost all known antibiotics.

31 Oct 2023

Surfing the web too much? Study links problematic internet use to heightened ADHD symptoms

This meta-analysis reveals a significant association between problematic internet use (PIU) and symptoms of ADHD, particularly in adult males who are not clinically diagnosed. The study emphasizes the need for further research on potential interventions for managing internet use and ADHD symptoms.

30 Oct 2023

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

The efficacy of the bivalent Pfizer-BioNTech COVID-19 messenger ribonucleic acid (mRNA) vaccine BNT162b2 BA.4/5.

30 Oct 2023

New bivalent vaccine shows promising results against key fish pathogens

The efficacy of a bivalent vaccine against Aeromonas hydrophila (A. hydrophila) and Streptococcus agalactiae (S. agalactiae).

30 Oct 2023

Rise in skin cancer cases underscores importance of early detection using machine learning

Image-processing techniques in machine learning (ML) for skin cancer detection using clinical images.

30 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

Study finds that anti-ERBB2 inhibitors used in breast cancer treatment pose significant risks to pregnancy and fetal health, including higher likelihoods of congenital defects and intrauterine growth restriction. Researchers recommend careful monitoring and possibly discontinuing these drugs during pregnancy despite their effectiveness against cancer.

29 Oct 2023

Redefining the battle against Alzheimer's with tau-focused treatments

Researchers explore the potential of tau-targeting therapies in treating Alzheimer's disease, focusing on immunotherapies and strategies to improve their efficacy. The study dives into the complex biology of tau proteins, their modifications, and how they can be targeted to halt the progression of Alzheimer's.

29 Oct 2023

New insights into how menopause affects women’s lives, health, workplaces

A sweeping new paper on menopause by a UVA Health expert and collaborators highlights the profound and sometimes surprising effects the “change of life” can have on women’s lives, health, workplaces and even finances.

28 Oct 2023

RF-CBT reduces rumination and shifts brain connectivity in adolescents with depression

A new study from The Ohio State University Wexner Medical Center and College of Medicine, University of Utah and University of Exeter (UK) substantiates previous groundbreaking research that rumination (overthinking) can be reduced through an intervention called Rumination-focused Cognitive Behavioral Therapy (RF-CBT).

27 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

The differential effects of low-carb diet and habitual diet on the fecal level of short-chain fatty acid

The fecal levels of short-chain fatty acid (SCFA) and serum inflammatory markers.

27 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

New nanoparticle-based system developed for comprehensive treatment of rheumatoid arthritis

A team of scientists led by KOO Sagang from the Seoul National University and Center for Nanoparticle Research within the Institue for Basic Science Center (IBS), in collaboration with researchers from Korea Institute of Science and Technology (KIST) and the Seoul National University, developed a new solution for the treatment of rheumatoid arthritis (RA).

26 Oct 2023

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc.

25 Oct 2023

Efficacy News and Research

Augmentation therapy can save lives of people with alpha-1 antitrypsin deficiency, study shows

JAK inhibitors offer effective and convenient treatment option for arthritis patients

Managing menopause: The 2023 toolkit for healthcare practitioners

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Researchers harness a combination of lab-grown cells to regenerate damaged heart muscle

AI may help identify potential gonorrhea vaccine proteins

Surfing the web too much? Study links problematic internet use to heightened ADHD symptoms

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

New bivalent vaccine shows promising results against key fish pathogens

Rise in skin cancer cases underscores importance of early detection using machine learning

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

Redefining the battle against Alzheimer's with tau-focused treatments

New insights into how menopause affects women’s lives, health, workplaces

RF-CBT reduces rumination and shifts brain connectivity in adolescents with depression

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

The differential effects of low-carb diet and habitual diet on the fecal level of short-chain fatty acid

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

New nanoparticle-based system developed for comprehensive treatment of rheumatoid arthritis

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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