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New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications.

25 Aug 2022

Investigating the links between the rate of new cases, mutations, and selection in SARS-CoV2 virus

How many times in the last 18 months have you seen a map that looks like the one above? It looks like a population density map, but in fact, it is a case total for the COVID19 rates from Johns Hopkins Coronavirus Research Center (collected on 24 May 2022).

25 Aug 2022

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

In a new study, researchers assessed the impact of mutagenesis on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and the effects of mutations in the neutral regions and non-neutral regions of the genome.

25 Aug 2022

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

A recent study investigated ‘targets’ in the poxvirus and identified the protein residues active in MPV, following which eight potential anti-viral drugs were proposed.

25 Aug 2022

Researchers discover a new class of more potent and less toxic drugs for leukemia patients

Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer.

24 Aug 2022

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

T cells used in immunotherapy treatments can get exhausted by the task of fighting cancer cells or get shutdown as they enter tumors.

24 Aug 2022

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

An international team of scientists have demonstrated for the first time that CRISPR genome-editing technology can be used as a tool to find new gene therapies for lung cancer.

24 Aug 2022

Strong facial similarity in people is linked with shared genetic variants

A collection of photos of genetically unrelated lookalikes, along with DNA analysis, revealed that strong facial similarity is associated with shared genetic variants.

23 Aug 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022

Case report describes clinical manifestation of monkeypox, SARS-CoV-2, and HIV coinfection

Scientists have recently presented the first documented case of coinfection with monkeypox virus, SARS-CoV-2, and HIV.

23 Aug 2022

Investigating the missing link between COVID-19 and anosmia

A new study evaluated how SARS-CoV-2 infection leads to anosmia via chromatin structure disruption and OR dysregulation. For this purpose, publicly available Hi-C data of OSNs of SARS-CoV-2-infected and control human subjects were used.

23 Aug 2022

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

A new study addresses the important question of how the SARS-CoV-2 virus would evolve in the future to be able to escape diverse and broadly neutralizing antibodies.

23 Aug 2022

Insights into the biology of the monkeypox virus

Researchers provided insights into monkeypox virus structural characteristics, epidemiology, transmission, zoonotic reservoirs, pathogenesis, and clinical management.

23 Aug 2022

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Imagine you're trying to do a job and all of the information you need to do it is in a few books at the library.

22 Aug 2022

CDC releases investigation notice regarding outbreak of E. coli O157 infections in Michigan and Ohio

A CDC investigation notice regarding a multistate outbreak of E. coli O157 infections is now live: https://www.cdc.gov/ecoli/2022/o157h7-08-22/index.html

22 Aug 2022

Polygenic risk score identifies coronary artery disease patients at risk for sudden cardiac death.

Researchers in the Smidt Heart Institute at Cedars-Sinai are one step closer to identifying patients at highest risk for developing sudden cardiac death - an electrical malfunction in the heart that causes it to stop beating.

22 Aug 2022

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers at the Centre for Genomic Regulation have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

22 Aug 2022

Study reveals the unique and unconventional way mosquitoes process odors

If you've ever sprayed yourself head to toe in bug repellent, yet still felt like a mosquito magnet, it will come as no shock to you that mosquitoes are very, very good at finding humans to bite.

19 Aug 2022

SARS-CoV-2 variant neutralization and novel mAbs reveal protection against Omicron in new research

Researchers assessed the SARS-CoV-2 variants of concern (VOCs) transmission dynamics and neutralization by vaccine-induced antibodies and monoclonal antibodies (mAbs).

19 Aug 2022

Combination of new testing methods helps identify multiple dementia risk genes

A new UCLA-led study has identified multiple new risk genes for Alzheimer's disease and a rare, related brain disorder called progressive supranuclear palsy (PSP) by using a combination of new testing methods allowing for mass screening of genetic variants in a single experiment.

18 Aug 2022

Genome News and Research

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

Investigating the links between the rate of new cases, mutations, and selection in SARS-CoV2 virus

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

Researchers discover a new class of more potent and less toxic drugs for leukemia patients

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

Strong facial similarity in people is linked with shared genetic variants

Common molecular tool for DNA labelling shows unexpected anticancer properties

Case report describes clinical manifestation of monkeypox, SARS-CoV-2, and HIV coinfection

Investigating the missing link between COVID-19 and anosmia

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

Insights into the biology of the monkeypox virus

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

CDC releases investigation notice regarding outbreak of E. coli O157 infections in Michigan and Ohio

Polygenic risk score identifies coronary artery disease patients at risk for sudden cardiac death.

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Study reveals the unique and unconventional way mosquitoes process odors

SARS-CoV-2 variant neutralization and novel mAbs reveal protection against Omicron in new research

Combination of new testing methods helps identify multiple dementia risk genes

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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